Effects of supraphysiological doses of levothyroxine on sleep in healthy subjects: a prospective polysomnography study [0.03%]
左旋甲状腺素在健康受试者中的超生理剂量对睡眠的影响:一项前瞻性多导睡眠图研究
Susanne Kraemer,Heidi Danker-Hopfe,Maximilian Pilhatsch et al.
Susanne Kraemer et al.
Disrupted sleep is prevalent in both mood and thyroid disorders. Given the emerging use of thyroid hormones in the treatment of mood disorders, we investigated the effects of supraphysiological doses of levothyroxine (L-T4) on sleep. In an ...
John H Lazarus
John H Lazarus
There is a high incidence of thyroid dysfunction during pregnancy resulting in adverse maternal (miscarriages, anaemia in pregnancy, preeclampsia, abruptio placenta and post-partum haemorrhage) and fetal effects (premature birth, low birth ...
The role of hypothalamic tri-iodothyronine availability in seasonal regulation of energy balance and body weight [0.03%]
下丘脑三碘甲状腺原氨酸在季节性能量平衡和体重调节中的作用
Michelle Murphy,Francis J P Ebling
Michelle Murphy
Seasonal cycles of body weight provide a natural model system to understand the central control of energy balance. Studies of such cycles in Siberian hamsters suggest that a change in the hypothalamic availability of thyroid hormone is the ...
Predominant RET Germline Mutations in Exons 10, 11, and 16 in Iranian Patients with Hereditary Medullary Thyroid Carcinoma [0.03%]
伊朗遗传性髓样甲状腺癌患者RET基因第10、11和16外显子纯合 germline突变为主导
Mehdi Hedayati,Marjan Zarif Yeganeh,Sara Sheikhol Eslami et al.
Mehdi Hedayati et al.
Medullary thyroid carcinoma occurs in both sporadic (75%) and hereditary (25%) forms. The missense mutations of RET proto-oncogene in MTC development have been well demonstrated. To investigate the spectrum of predominant RET germline mutat...
Bipul Kumar Choudhury,Uma Kaimal Saikia,Dipti Sarma et al.
Bipul Kumar Choudhury et al.
Dual ectopic thyroid is a rare presentation of thyroid ectopia. Only a few cases have been reported in the world literature. Dual ectopic thyroid in the presence of a normally located thyroid is even rarer. We report a case of dual ectopic ...
Case Reports
Journal of thyroid research. 2011:2011:159703. DOI:10.4061/2011/159703 2011
Fabrice Chatonnet,Frédéric Picou,Teddy Fauquier et al.
Fabrice Chatonnet et al.
Thyroid hormones (TH, including the prohormone thyroxine (T4) and its active deiodinated derivative 3,3',5-triiodo-L-thyronine (T3)) are important regulators of vertebrates neurodevelopment. Specific transporters and deiodinases are require...
J Lindholm,P Laurberg
J Lindholm
The last part of the 19th century was a period of great achievements in medicine and endocrinology. The thyroid gland evolved from being considered a rudimentary structure to an organ related to specific diseases. The singular importance of...
Gabriella Mincione,Maria Carmela Di Marcantonio,Chiara Tarantelli et al.
Gabriella Mincione et al.
Normal epithelial thyroid cells in culture are inhibited by TGF-β1. Instead, transformed thyroid cell lines are frequently resistant to its growth inhibitory effect. Loss of TGF-β responsiveness could be due to a reduced expression of TGF...
Thyroid hormone receptors in two model species for vertebrate embryonic development: chicken and zebrafish [0.03%]
两种脊椎动物胚胎发育模型物种中的甲状腺激素受体:鸡和斑马鱼
Veerle M Darras,Stijn L J Van Herck,Marjolein Heijlen et al.
Veerle M Darras et al.
Chicken and zebrafish are two model species regularly used to study the role of thyroid hormones in vertebrate development. Similar to mammals, chickens have one thyroid hormone receptor α (TRα) and one TRβ gene, giving rise to three TR ...
Thyroid hormone receptor mutations in cancer and resistance to thyroid hormone: perspective and prognosis [0.03%]
甲状腺激素受体突变与癌症及抵抗甲状腺激素的作用机制及预后展望
Meghan D Rosen,Martin L Privalsky
Meghan D Rosen
Thyroid hormone, operating through its receptors, plays crucial roles in the control of normal human physiology and development; deviations from the norm can give rise to disease. Clinical endocrinologists often must confront and correct th...