Stephen T Wu,Vinod C Kaggal,Dmitriy Dligach et al.
Stephen T Wu et al.
Background: One challenge in reusing clinical data stored in electronic medical records is that these data are heterogenous. Clinical Natural Language Processing (NLP) plays an important role in transforming information i...
Charalampos Doulaverakis,George Nikolaidis,Athanasios Kleontas et al.
Charalampos Doulaverakis et al.
Background: Identification of drug-drug and drug-diseases interactions can pose a difficult problem to cope with, as the increasingly large number of available drugs coupled with the ongoing research activities in the pha...
Ontology-based time information representation of vaccine adverse events in VAERS for temporal analysis [0.03%]
基于本体的疫苗不良事件时间信息表示方法及其在VAERS中的应用
Cui Tao,Yongqun He,Hannah Yang et al.
Cui Tao et al.
Background: The U.S. FDA/CDC Vaccine Adverse Event Reporting System (VAERS) provides a valuable data source for post-vaccination adverse event analyses. The structured data in the system has been widely used, but the info...
Identification of fever and vaccine-associated gene interaction networks using ontology-based literature mining [0.03%]
基于本体的文献挖掘鉴定发热和疫苗相关基因相互作用网络
Junguk Hur,Arzucan Ozgür,Zuoshuang Xiang et al.
Junguk Hur et al.
Background: Fever is one of the most common adverse events of vaccines. The detailed mechanisms of fever and vaccine-associated gene interaction networks are not fully understood. In the present study, we employed a genom...
Ontology representation and analysis of vaccine formulation and administration and their effects on vaccine immune responses [0.03%]
疫苗制备与接种及其对疫苗免疫应答的影响的本体构建与分析
Yu Lin,Yongqun He
Yu Lin
Background: A vaccine is a processed material that if administered, is able to stimulate an adaptive immune response to prevent or ameliorate a disease. A vaccination process may protect the host against subsequent exposu...
Qian Zhu,Guoqian Jiang,Christopher G Chute
Qian Zhu
Background: Structured Product Labeling (SPL) is a document markup standard approved by Health Level Seven (HL7) and adopted by United States Food and Drug Administration (FDA) as a mechanism for exchanging drug product i...
Harsha Gurulingappa,Abdul Mateen-Rajput,Luca Toldo
Harsha Gurulingappa
: The sheer amount of information about potential adverse drug events published in medical case reports pose major challenges for drug safety experts to perform timely monitoring. Efficient strategies for identification and extraction of in...
A 2012 Workshop: Vaccine and Drug Ontology in the Study of Mechanism and Effect (VDOSME 2012) [0.03%]
疫苗和药物机制和效应研究的本体论（VDOSME 2012）研讨会预告
Yongqun He,Luca Toldo,Gully Burns et al.
Yongqun He et al.
Vaccines and drugs have contributed to dramatic improvements in public health worldwide. Over the last decade, there have been efforts in developing biomedical ontologies that represent various areas associated with vaccines and drugs. Thes...
Tim Beck,Robert C Free,Gudmundur A Thorisson et al.
Tim Beck et al.
Background: The amount of data generated from genome-wide association studies (GWAS) has grown rapidly, but considerations for GWAS phenotype data reuse and interchange have not kept pace. This impacts on the work of GWAS...
Eleni Mikroyannidi,Robert Stevens,Luigi Iannone et al.
Eleni Mikroyannidi et al.
Motivation: In this paper we demonstrate the usage of RIO; a framework for detecting syntactic regularities using cluster analysis of the entities in the signature of an ontology. Quality assurance in ontologies is vital ...