Marta Costa,Simon Reeve,Gary Grumbling et al.
Marta Costa et al.
Background: Anatomy ontologies are query-able classifications of anatomical structures. They provide a widely-used means for standardising the annotation of phenotypes and expression in both human-readable and programmati...
Enhanced XAO: the ontology of Xenopus anatomy and development underpins more accurate annotation of gene expression and queries on Xenbase [0.03%]
增强的XAO：非洲爪蟾解剖和发育本体论支持更准确地注释基因表达和查询 Xenbase中的信息
Erik Segerdell,Virgilio G Ponferrada,Christina James-Zorn et al.
Erik Segerdell et al.
Background: The African clawed frogs Xenopus laevis and Xenopus tropicalis are prominent animal model organisms. Xenopus research contributes to the understanding of genetic, developmental and molecular mechanisms underly...
David Osumi-Sutherland,Steven J Marygold,Gillian H Millburn et al.
David Osumi-Sutherland et al.
Background: Phenotype ontologies are queryable classifications of phenotypes. They provide a widely-used means for annotating phenotypes in a form that is human-readable, programatically accessible and that can be used to...
Automatically transforming pre- to post-composed phenotypes: EQ-lising HPO and MP [0.03%]
自动将前期到后期表型的转化：EQ表述HPO和MP
Anika Oellrich,Christoph Grabmüller,Dietrich Rebholz-Schuhmann
Anika Oellrich
Background: Large-scale mutagenesis projects are ongoing to improve our understanding about the pathology and subsequently the treatment of diseases. Such projects do not only record the genotype but also report phenotype...
Evaluating gold standard corpora against gene/protein tagging solutions and lexical resources [0.03%]
评估黄金标准语料库、基因/蛋白质标注方案及词源资源之间的关系
Dietrich Rebholz-Schuhmann,Senay Kafkas,Jee-Hyub Kim et al.
Dietrich Rebholz-Schuhmann et al.
Motivation: The identification of protein and gene names (PGNs) from the scientific literature requires semantic resources: Terminological and lexical resources deliver the term candidates into PGN tagging solutions and t...
Irena Spasić,Mark Greenwood,Alun Preece et al.
Irena Spasić et al.
Background: The increasing amount of textual information in biomedicine requires effective term recognition methods to identify textual representations of domain-specific concepts as the first step toward automating its s...
Function of dynamic models in systems biology: linking structure to behaviour [0.03%]
系统生物学中动态模型的作用：结构与行为的关联
Christian Knüpfer,Clemens Beckstein
Christian Knüpfer
Background: Dynamic models in Systems Biology are used in computational simulation experiments for addressing biological questions. The complexity of the modelled biological systems and the growing number and size of the ...
Developing a semantically rich ontology for the biobank-administration domain [0.03%]
用于生物样本库管理领域的语义丰富本体的开发
Mathias Brochhausen,Martin N Fransson,Nitin V Kanaskar et al.
Mathias Brochhausen et al.
Background: Biobanks are a critical resource for translational science. Recently, semantic web technologies such as ontologies have been found useful in retrieving research data from biobanks. However, recent research has...
Functional tissue units and their primary tissue motifs in multi-scale physiology [0.03%]
多尺度生理学中的功能组织单元及其基本组织动机
Bernard de Bono,Pierre Grenon,Richard Baldock et al.
Bernard de Bono et al.
Background: Histology information management relies on complex knowledge derived from morphological tissue analyses. These approaches have not significantly facilitated the general integration of tissue- and molecular-lev...
Catia M Machado,Ana T Freitas,Francisco M Couto
Catia M Machado
: Enrichment analysis is well established in the field of transcriptomics, where it is used to identify relevant biological features that characterize a set of genes obtained in an experiment.This article proposes the application of enrichm...