Ontology-based literature mining and class effect analysis of adverse drug reactions associated with neuropathy-inducing drugs [0.03%]
基于本体的文献挖掘及神经病药物不良反应类效应分析
Junguk Hur,Arzucan Özgür,Yongqun He
Junguk Hur
Background: Adverse drug reactions (ADRs), also called as drug adverse events (AEs), are reported in the FDA drug labels; however, it is a big challenge to properly retrieve and analyze the ADRs and their potential relati...
Modularising ontology and designing inference patterns to personalise health condition assessment: the case of obesity [0.03%]
模块化本体构建及设计推理模式以个性化健康状况评估：肥胖症案例分析
Aleksandra Sojic,Walter Terkaj,Giorgia Contini et al.
Aleksandra Sojic et al.
Background: The public health initiatives for obesity prevention are increasingly exploiting the advantages of smart technologies that can register various kinds of data related to physical, physiological, and behavioural...
Querying archetype-based EHRs by search ontology-based XPath engineering [0.03%]
基于搜索本体的XPath工程查询架构化电子健康记录系统
Stefan Kropf,Alexandr Uciteli,Katrin Schierle et al.
Stefan Kropf et al.
Background: Legacy data and new structured data can be stored in a standardized format as XML-based EHRs on XML databases. Querying documents on these databases is crucial for answering research questions. Instead of usin...
Extending the DIDEO ontology to include entities from the natural product drug interaction domain of discourse [0.03%]
扩展DIDEO本体以包含来自天然产物药物相互作用领域实体的内容
John Judkins,Jessica Tay-Sontheimer,Richard D Boyce et al.
John Judkins et al.
Background: Prompted by the frequency of concomitant use of prescription drugs with natural products, and the lack of knowledge regarding the impact of pharmacokinetic-based natural product-drug interactions (PK-NPDIs), t...
GGDonto ontology as a knowledge-base for genetic diseases and disorders of glycan metabolism and their causative genes [0.03%]
GGDonto本体作为一种糖类代谢遗传疾病及其致病基因的知识库
Elena Solovieva,Toshihide Shikanai,Noriaki Fujita et al.
Elena Solovieva et al.
Background: Inherited mutations in glyco-related genes can affect the biosynthesis and degradation of glycans and result in severe genetic diseases and disorders. The Glyco-Disease Genes Database (GDGDB), which provides i...
Deep learning meets ontologies: experiments to anchor the cardiovascular disease ontology in the biomedical literature [0.03%]
深度学习与本体论的结合：在生物医学文献中锚定心血管疾病本体论的实验
Mercedes Arguello Casteleiro,George Demetriou,Warren Read et al.
Mercedes Arguello Casteleiro et al.
Background: Automatic identification of term variants or acceptable alternative free-text terms for gene and protein names from the millions of biomedical publications is a challenging task. Ontologies, such as the Cardio...
Clinical Natural Language Processing in languages other than English: opportunities and challenges [0.03%]
英语以外的语言的临床自然语言处理：机遇与挑战
Aurélie Névéol,Hercules Dalianis,Sumithra Velupillai et al.
Aurélie Névéol et al.
Background: Natural language processing applied to clinical text or aimed at a clinical outcome has been thriving in recent years. This paper offers the first broad overview of clinical Natural Language Processing (NLP) f...
Mengyi Zhao,Songmao Zhang,Weizhuo Li et al.
Mengyi Zhao et al.
Background: The goal of ontology matching is to identify correspondences between entities from different yet overlapping ontologies so as to facilitate semantic integration, reuse and interoperability. As a well developed...
Using OWL reasoning to support the generation of novel gene sets for enrichment analysis [0.03%]
利用OWL推理支持新颖基因集的生成以增强丰富度分析
David J Osumi-Sutherland,Enrico Ponta,Melanie Courtot et al.
David J Osumi-Sutherland et al.
Background: The Gene Ontology (GO) consists of over 40,000 terms for biological processes, cell components and gene product activities linked into a graph structure by over 90,000 relationships. It has been used to annota...
Asan Agibetov,Ernesto Jiménez-Ruiz,Marta Ondrésik et al.
Asan Agibetov et al.
Background: Pathogenesis of inflammatory diseases can be tracked by studying the causality relationships among the factors contributing to its development. We could, for instance, hypothesize on the connections of the pat...