Criterion for Assessing Accumulated Neurotoxicity of Alpha-Synuclein Oligomers in Parkinson's Disease [0.03%]
帕金森病中α-突触核蛋白寡聚体积累神经毒性的评判标准
Andrey V Kuznetsov
Andrey V Kuznetsov
The paper introduces a parameter called "accumulated neurotoxicity" of α-syn oligomers, which measures the cumulative damage these toxic species inflict on neurons over time, given the years it typically takes for such damage to manifest. ...
Validation of a Microfluidic Device Prototype for Cancer Detection and Identification: Circulating Tumor Cells Classification Based on Cell Trajectory Analysis Leveraging Cell-Based Modeling and Machine Learning [0.03%]
基于细胞轨迹分析的循环肿瘤细胞分类模型的验证：结合细胞建模和机器学习方法检测和识别癌症原型微流控芯片的验证研究
Rifat Rejuan,Eugenio Aulisa,Wei Li et al.
Rifat Rejuan et al.
Microfluidic devices (MDs) present a novel method for detecting circulating tumor cells (CTCs), enhancing the process through targeted techniques and visual inspection. However, current approaches often yield heterogeneous CTC populations, ...
Estimation of Active Tension in Cardiac Microtissues by Solving a PDE-Constrained Optimization Problem [0.03%]
基于求解约束偏微分方程的最优化问题的心肌组织活性张力估计方法研究
Åshild Telle,Verena Charwat,Bérénice Charrez et al.
Åshild Telle et al.
Microphysiological systems (MPS) provide a highly controlled environment for the development and testing of human-induced pluripotent stem cell-based cardiac microtissues, with promising applications in disease modeling and drug development...
Constitutive Models for Active Skeletal Muscle: Review, Comparison, and Application in a Novel Continuum Shoulder Model [0.03%]
主动骨骼肌的本构模型：综述、比较及在新型连续肩部模型中的应用
Laura Engelhardt,Renate Sachse,Rainer Burgkart et al.
Laura Engelhardt et al.
The shoulder joint is one of the functionally and anatomically most sophisticated articular systems in the human body. Both complex movement patterns and the stabilization of the highly mobile joint rely on intricate three-dimensional inter...
Daehan Wi,Hoyul Lee,Woo Shik Jeong et al.
Daehan Wi et al.
Traditional surgical interventions for frontal sinus fractures necessitate a cut on the forehead skin, and extant closed reduction techniques aimed at enhancing accessibility continue to grapple with secure tool fixation, stable bone elevat...
Comparative Analysis of Various Cavosurface Margins in Class II Restorations Using 3D Finite Element Method [0.03%]
三维有限元法分析二类洞修复体不同牙本质边缘的比较研究
Zuzanna Apel,Behzad Vafaeian,Joanna Zarzecka et al.
Zuzanna Apel et al.
The primary aim of these analyses was to evaluate the mechanical characteristics of the restored proximal surface of the lower first molar by comparing four different preparation designs: (a) slot preparation, (b) slot preparation with beve...
Finite Element Modeling of Abdominal Near-Infrared Spectroscopy for Infant Splanchnic Oximetry [0.03%]
婴儿肠系膜氧合近红外光谱腹部有限元建模
Vishnu S Emani,Caglar Ozturk,Manisha Singh et al.
Vishnu S Emani et al.
Abdominal near-infrared spectroscopy (NIRS) holds promise for early detection of necrotizing enterocolitis and other infant pathologies prior to irreversible injury, but the optimal NIRS sensor design is not well defined. In this study, we ...
An Efficient Staggered Scheme for Solving the Poromechanics Problem of Quasi-Static Cardiac Perfusion [0.03%]
一种求解准静态心脏灌注poro mechanics问题的有效交替方向隐式算法
Xuan Wang,Li Cai,Pengfei Ma et al.
Xuan Wang et al.
The ventricles can be considered a type of poroelastic material, where the mass and pressure of the interstitial fluid, along with the displacement of the skeleton, are the three primary physical quantities of interest. Based on the free en...
A Neural Network Finite Element Trileaflet Heart Valve Model Incorporating Multi-Body Contact [0.03%]
一种多体接触的心脏三叶瓣膜神经网络有限元模型
Kenneth Meyer,Christian Goodbrake,Michael S Sacks
Kenneth Meyer
The use of patient-specific computational modeling of cardiovascular diseases has become increasingly popular to improve patient standard of care. Most simulation approaches currently utilize the finite element method (FEM), which is very w...
Effect of Arterial Blood Flow on Magnetic Nanoparticle Thermotherapy Applied on a Realistic Breast Tumor Model [0.03%]
动脉血流对乳腺肿瘤磁热疗影响的仿真研究
Sandeep Nain,Neeraj Kumar,Pramod Kumar Avti
Sandeep Nain
The current investigation aims to determine the effects of blood flow through the artery system engulfed in the tumor region, exposed to localized heating during magnetic nanoparticle hyperthermia (MNPH). The MNPH simulations are performed ...