Micro- and Nanoplastics Exposure Across the Lifespan: One Health Implications for Aging and Longevity [0.03%]
微塑料和纳米塑料的终生暴露：对老龄化和长寿的“同一健康”影响
Chantalle Moulton,Anna Baroni,Ennio Tasciotti
Chantalle Moulton
Micro- and nanoplastics (MNPs) are pervasive environmental contaminants with growing relevance for human health across the lifespan. Older adults may be especially vulnerable to their effects due to cumulative lifetime exposure, age-related...
Glyphosate-Induced Metabolic and Immune Modulation in Hepatoma Cells: Identification of Key Genes as Diagnostic and Therapeutic Targets Using an In Silico Systems Biology Approach [0.03%]
基于系统生物学的模拟方法在肝癌细胞中鉴定草甘膦诱导的关键代谢及免疫调控基因作为诊断和治疗靶点研究
Divya Mishra
Divya Mishra
Glyphosate, one of the most widely used herbicides worldwide, has raised significant concerns regarding its potential involvement in hepatotoxicity and molecular changes associated with liver cancer biology. These concerns highlight the nee...
Auxiliary TARP Subunits Define AMPA Receptor Pharmacology and Function [0.03%]
辅助TARP亚基定义了AMPA受体的药理学和功能
Sosana Bdir,İrfan Çapan,Mohammed Hawash et al.
Sosana Bdir et al.
Background: Fast excitatory transmission in the central nervous system is carried out by AMPA-type glutamate receptors. Neuronal hyperexcitability and epilepsy have been associated with the dysregulation of AMPA receptor ...
Polyethylene Mulch Emissions Differentially Impact the Soil Metabolome and Microbial Community in Field Pea (Pisum sativum L.) Cultivation [0.03%]
地膜排放物对田间豌豆种植中土壤代谢组和微生物群落的影响不同
Emoke Dalma Kovacs,Nguyen Khoi Nghia,Melinda Haydee Kovacs
Emoke Dalma Kovacs
Background and objectives: Polyethylene (PE) mulching enhances crop productivity through microclimate optimization but introduces synthetic polymer-derived compounds into agricultural soils. Despite widespread use, bioche...
Cyclophosphamide-Induced Nephrotoxicity and Nephroprotection in Rodent Models: A Systematic Review and Random-Effects Meta-Analysis (2010-2025) [0.03%]
环磷酰胺引起的啮齿类动物模型肾毒性和肾保护的系统性回顾和随机效应meta分析（2010-2025）
Denis Oberiukhtin,Anton Chernitskiy,Desheng Hu et al.
Denis Oberiukhtin et al.
Cyclophosphamide (CP) is extensively used in oncology and as an immunosuppressant, but dose-limiting renal injury remains a major constraint. We systematically reviewed in vivo rodent models of CP nephrotoxicity (2010-2025) and meta-analyse...
Enzyme-Targeted Antiproliferative Effects of Novel Indole-Acrylamide Xenobiotics Acting on Cyclooxygenase Pathways [0.03%]
新型吲哚-丙烯酰胺类外源化合物通过环氧化酶途径作用于酶的抗增殖效果研究
Mohammed Hawash,Benay Mahmutoğlu,Murad Abualhasan et al.
Mohammed Hawash et al.
The indole scaffold is common in natural products and bioactive compounds, including anti-cancer and anti-inflammatory medicines. In this work, a series of indole-acrylamide derivatives was synthesized, and their antiproliferative and anti-...
Pesticide Behavior in Soil Amended with Agricultural Waste and Agro-Industrial Byproducts: An Updated Review [0.03%]
有机废弃物和农产品加工副产品改良土壤中农药的行为:最新综述
Gabriel Pérez-Lucas,Simón Navarro
Gabriel Pérez-Lucas
Farmers rely on pesticides to keep their crops safe from pests, diseases, and weeds. However, if pesticides are not used properly, they can have serious consequences for human and environmental health. Many pesticides are not easily biodegr...
Fluorescent Dyes in Hydrological Tracing: Application Methods, Ecotoxicological Effects, and Safe Application Levels [0.03%]
用于水文示踪的荧光染料：应用方法、生态毒性效应及安全使用浓度
Carlos J A Campos,Louis A Tremblay,Olivier Champeau et al.
Carlos J A Campos et al.
Fluorescent dyes are commonly used as tracers in hydrological investigations to quantify transport pathways, residence times, mixing behavior, and connectivity in surface water, groundwater, and coastal systems. Despite their long history o...
Fungal Transformation and Oxalate-Mediated Mineralization of Heavy Metal Oxides by Aspergillus aculeatus [0.03%]
曲霉对重金属氧化物的真菌转化和草酸矿化作用
Thanakorn Sawangchart,Sutee Chutipaijit,Bunyarit Meksiriporn et al.
Thanakorn Sawangchart et al.
Fungal transformation is increasingly recognized as an important process influencing metal solubilization and immobilization in soil environments. In this study, a fungal strain (PTW4) isolated from mining-contaminated soil was molecularly ...
Impact of Cannabis and Cannabis Legalization on US Atrial Septal Defect Rates [0.03%]
大麻及大麻合法化对美国房间隔缺损发病率的影响
Albert Stuart Reece,Gary Kenneth Hulse
Albert Stuart Reece
Atrial septal defect (ASD) affects 1:11.3 children in some US states; however, the antecedents of these trends are yet to be identified. A total of 1882 ASD rates (ASDRs) for 2003-2020 were sourced from the National Birth Defects Prevention...