Lucio Capurso,Maurizio Koch
Lucio Capurso
Patients with IBD are at increased risk of developing Clostridium difficile (CD) infection and have worse outcomes, including higher rates of colectomy and death, and experience higher rates of recurrence. However, it is still not clear whe...
[Probiotics for the antibiotics associated diarrhea and for Clostridium difficile infection] [0.03%]
益生菌治疗抗生素相关性腹泻及艰难梭菌感染
Lucio Capurso,Maurizio Koch
Lucio Capurso
The term probiotic refers to live microorganisms that survive passage through the gastrointestinal tract and have beneficial effects on the host. Many strains of probiotic microorganisms have been shown to inhibit growth and metabolic activ...
[Side effects of antibiotic: diarrhea and Clostridium difficile infection] [0.03%]
抗生素的不良反应：腹泻和艰难梭菌感染
Lucio Capurso,Maurizio Koch
Lucio Capurso
Antibiotics are some of the most frequently prescribed medications worldwide, but antibiotic therapy may disturb the colonization resistance of gut microbiota to pathogenic bacteria, resulting in a range of symptoms that include, most notab...
Maurizio Koch,Lucio Capurso
Maurizio Koch
These are excellent times for probiotic medicine. We have discovered more than 150,000 genomes of the microbiome, which can be aggregated into 4,930 species. However, the dream of microbiome-based medicine requires a new approach - an ecolo...
Identification of anaplastic lymphoma kinase fusion in clear cell renal carcinoma (ALK-tRCC): a precision oncology medicine case report [0.03%]
明确透明细胞肾癌中的间变性淋巴瘤激酶融合蛋白（ALK-tRCC）：一例精确诊断和治疗病例报告
Veronica Varchetta,Carla Campanella,Michele Rossi et al.
Veronica Varchetta et al.
Background: Translocation-associated renal cell carcinoma involving ALK (ALK-tRCC) is a rare subtype of adult renal cell carcinoma (RCC) reported in recent years. ...
[Efficacy of pralsetinib in a patient with advanced lung adenocarcinoma positive for RET rearrangement: the importance of Comprehensive Genomic Profiling] [0.03%]
普拉西替尼治疗RET重排阳性晚期肺腺癌患者的疗效——综合基因组检测的重要性
Michele Montrone,Vito Longo,Annamaria Catino et al.
Michele Montrone et al.
Modern gene profiling techniques have allowed in recent years considerable progresses in the knowledge of molecular alterations in the context of non-small cell lung cancer (NSCLC). In some cases, these alterations have been recognized as h...
[Detection of novel driver mutations in liquid biopsy: case report of a RET-positive lung adenocarcinoma treated with pralsetinib] [0.03%]
[液体活检中检测新型驱动基因突变：接受普拉曲塞治疗的RET阳性肺腺癌病例报告]
Marco Russano
Marco Russano
Advances in cancer biology research led to the identification of new molecular drivers in non-small cell lung cancer. These alterations should be searched especially in young and never-smoker patients, in order to ensure access to targeted ...
[Comprehensive genomic profiling in large cell neuroendocrine lung cancer: the times they are a-changin'] [0.03%]
大细胞神经内分泌型肺癌的全面基因组分析：变革的时代不容忽视
Marco Filetti,Marta Piras,Raffaele Giusti
Marco Filetti
The discovery of gene driver mutations and the increase of next-generation sequencing techniques have radically changed the natural history of NSCLCs. Neuroendocrine lung cancers are a heterogeneous entity whose biology is little known. Spo...