Integrating Palliative Care into the Management of Heart Failure with Reduced Ejection Fraction: A Practice Pearl [0.03%]
射血分数降低的心力衰竭患者缓和医疗的临床应用 pearls
Abigail Latimer,Christopher E Knoepke,Roger Winters
Abigail Latimer
Heart failure with reduced ejection fraction is a progressive, undulating syndrome with an unpredictable illness course featuring intermittent symptom exacerbations and periods of stability. The progressive, variable trajectory of the illne...
Patisiran for the Treatment of Transthyretin-mediated Amyloidosis with Cardiomyopathy [0.03%]
用于治疗ATTR介导的心肌病的药物Patisiran
Adam Ioannou,Marianna Fontana,Julian D Gillmore
Adam Ioannou
Transthyretin (TTR) is a tetrameric protein, synthesized primarily by the liver, that acts as a physiological transport protein for retinol and thyroxine. TTR can misfold into pathogenic amyloid fibrils that deposit in the heart and nerves,...
Peri- and Post-procedural Anticoagulation with Left Atrial Appendage Occlusion Devices [0.03%]
左心耳封堵术的围手术期和术后抗凝治疗
Pradyumna Agasthi,Sai Harika Pujari
Pradyumna Agasthi
In patients with atrial fibrillation and high stroke risk, anticoagulation with direct oral anticoagulants or vitamin K antagonists is the standard of care for stroke prevention. The benefit of anticoagulation is driven by attenuating the r...
Outcomes of Prediabetes Compared with Normoglycaemia and Diabetes Mellitus in Patients Undergoing Percutaneous Coronary Intervention: A Systematic Review and Meta-analysis [0.03%]
经皮冠状动脉介入治疗患者中糖尿病前期与正常血糖和糖尿病结局的比较：系统评价和 meta 分析
Muhammad Junaid Ahsan,Azka Latif,Soban Ahmad et al.
Muhammad Junaid Ahsan et al.
Background: Patients with prediabetes are at increased risk of coronary artery disease (CAD). However, the association between prediabetes and adverse clinical outcomes following percutaneous coronary intervention (PCI) is inconsistent, in ...
Measurement of Blood Volume in Patients with Heart Failure: Clinical Relevance, Surrogates, Historical Background and Contemporary Methodology [0.03%]
心力衰竭患者血容量测定：临床意义、替代标志物、历史背景及当代方法学研究
Wayne L Miller
Wayne L Miller
The development of clinical congestion resulting from volume overload, either by renal fluid retention or redistribution of blood volume from venous reservoirs, is a recurrent scenario in patients with chronic heart failure (HF). As a resul...
Nishant Sharma,Ayaaz K Sachedina,Sachin Kumar
Nishant Sharma
Aortic stenosis (AS) is a common valve pathology experienced by patients worldwide. There are limited population-based studies assessing its prevalence; however, epidemiological studies emphasize that the burden of disease is growing. Recog...
Globe Pulsed Field System for High-definition Mapping and Ablation for Atrial Fibrillation [0.03%]
高分辨率灌注标测和消融治疗心房颤动的全球脉冲场系统
Paula Sanchez-Somonte,Atul Verma
Paula Sanchez-Somonte
Pulmonary vein isolation (PVI) is the cornerstone of atrial fibrillation ablation. Radiofrequency ablation has been the most common source of energy used to achieve PVI until now. In recent years, cryoballoon ablation has gained popularity ...
Effect of Endothelial Adhesion Molecules on Atrial Fibrillation: A Systematic Review and Meta-analysis [0.03%]
血管内皮粘附分子对房颤影响的系统评价和 meta 分析
Mehran Rahimi,Leili Faridi,Leila Nikniaz et al.
Mehran Rahimi et al.
Background: Endothelial adhesion molecules (EAMs), and more specifically vascular cell adhesion molecule-1 (VCAM-1) and intercellular adhesion molecule-1 (ICAM-1), belong to a family of immunoglobulin-like molecules and are found to have in...
Strategies for Reducing Vascular and Bleeding Risk for Percutaneous Left Ventricular Assist Device-supported High-risk Percutaneous Coronary Intervention [0.03%]
经皮左心室辅助装置支持下的高危冠脉介入治疗降低血管和出血风险的策略
George W Vetrovec,Amir Kaki,Jason Wollmuth et al.
George W Vetrovec et al.
In patients at high risk for haemodynamic instability during percutaneous coronary intervention (PCI), practitioners are increasingly opting for prophylactic mechanical circulatory support, such as the Impella® heart pump (Abiomed, Danvers...
Saad M Ezad,Matthew Ryan,Divaka Perera
Saad M Ezad
Coronary artery disease (CAD) remains the most common cause of heart failure with reduced ejection fraction; despite its prevalence, there is limited evidence to guide physicians in managing patients with CAD with percutaneous revasculariza...