Saeed Bohlega
Saeed Bohlega
Mutations in the NOTCH3 gene are responsible for cerebral autosomal dominant arteriopathy with subcortical infarcts and leukoencephalopathy (CADASIL), an adult onset hereditary angiopathy leading to ischemic stroke, vascular dementia and ps...
Primary stroke prevention and hypertension treatment: which is the first-line strategy? [0.03%]
一级高血压治疗与卒中预防:孰轻孰重?
Roberta Ravenni,Joe F Jabre,Edoardo Casiglia et al.
Roberta Ravenni et al.
Hypertension (HT) is considered the main classic vascular risk factor for stroke and the importance of lowering blood pressure (BP) is well established. However, not all the benefit of antihypertensive treatment is due to BP reduction per s...
Benign fasciculations and corticosteroid use: possible association? An update [0.03%]
良性纤维颤动和皮质类固醇使用:可能的关联?更新报告
Marco Orsini,Flavio R Sztajnbok,Acary Bulle Oliveira et al.
Marco Orsini et al.
Fasciculations are characterized by visible subtle and fast contractions of muscle, even wormlike in movement, by the contraction of a fascicle of muscle fibers. The authors present the case study of a 28-year-old patient with the appearanc...
Case Reports
Neurology international. 2011 Jul 5;3(2):e11. DOI:10.4081/ni.2011.e11 2011
Behavioral outcome measures used for human neural stem cell transplantation in rat stroke models [0.03%]
用于人神经干细胞移植的卒中模型行为学评价方法
Matthew B Jensen,Dong Y Han,Abdullah Al Sawaf et al.
Matthew B Jensen et al.
Stroke is a leading cause of death and disability, leading to the development of various stroke models to test new treatments, most commonly in the rat. Human stroke trials focus on disability, related primarily to neurological deficits. To...
Influence of histocompatibility genes on disease susceptibility and treatment response in patients with relapsing-remitting multiple sclerosis treated with interferon β-1a [0.03%]
人类组织相容性基因对复发型多发性硬化症患者干扰素β-1а治疗疗效和疾病易感性的影响
Shlomo Flechter,Tirza Klein,Lea Pollak
Shlomo Flechter
Multiple sclerosis (MS) is the most common, non-traumatic cause of neurological disability in young adults. The aim of this study was to investigate the influence of HLA class II alleles DRB1* and DQB1* on susceptibility to relapsing-remitt...
Aline Furtado Bastos,Marco Orsini,Dionis Machado et al.
Aline Furtado Bastos et al.
The Amyotrophic lateral sclerosis (ALS) is the most common form of motor neuron disease in the adulthood, and it is characterized by rapid and progressive compromise of the upper and lower motor neurons. The majority of the cases of ALS are...
Marc A Lazzaro,Elizabeth J Cochran,Demetrius K Lopes et al.
Marc A Lazzaro et al.
Moyamoya syndrome is a rare cerebrovascular disorder characterized by progressive occlusion of the supraclinoid internal carotid artery and proximal portions of the anterior and middle cerebral arteries resulting in an extensive network of ...
Case Reports
Neurology international. 2011 Jun;3(1):e3. DOI:10.4081/ni.2011.e3 2011
Clinical, diagnostic and immunological characteristics of patients with possible neuroborreliosis without intrathecal Ig-synthesis against Borrelia antigen in the cerebrospinal fluid [0.03%]
可能的神经白喉症患者临床、诊断和免疫学特征(脑脊液中没有针对白喉杆菌抗原的体液Ig合成)
Magnus Vrethem,Mona Widhe,Jan Ernerudh et al.
Magnus Vrethem et al.
The diagnosis of neuroborreliosis is not always straightforward. Intrathecal immunoglobulin (Ig) synthesis against Borrelia antigen may not be detected, at least early in the disease course. Also other neurological and infectious diagnoses ...
Emily R Atkins,Peter K Panegyres
Emily R Atkins
Alzheimer's disease (AD) is the largest cause of dementia, affecting 35.6 million people in 2010. Amyloid precursor protein, presenilin 1 and presenilin 2 mutations are known to cause familial early-onset AD, whereas apolipoprotein E (APOE)...
Hypertensive brainstem encephalopathy involving deep supratentorial regions: does only blood pressure matter? [0.03%]
血压高才是高血压脑病累及桥脑的主要原因吗?
Jong-Ho Park,Sung-Min Kim,Hyung-Woo Shin et al.
Jong-Ho Park et al.
We report on a 42-year-old female patient who presented with high arterial blood pressure of 245/150 mmHg and hypertensive brainstem encephalopathy that involved the brainstem and extensive supratentorial deep gray and white matter. The les...
Case Reports
Neurology international. 2010 Jun 21;2(1):e9. DOI:10.4081/ni.2010.e9 2010