Variation of ATM Gene Expression in Peripheral Blood Cells of Sporadic Breast Carcinomas in Iranian Patients [0.03%]
伊朗乳腺癌患者的外周血细胞中ATM基因表达的差异性分析
Mohsen Foroughizadeh,Hossein Mozdarani,Keyvan Majidzadeh-A et al.
Mohsen Foroughizadeh et al.
The ataxia telangiectasia mutated gene (ATM), candidate for breast cancer susceptibility gene, encode a 350-kDa protein belongs to the core components of DNA-damage response machinery. Female AT carriers have at least 5-fold increase risk f...
The Effect of the Duration of In Vitro Maturation (IVM) on Parthenogenetic Development of Ovine Oocytes [0.03%]
体外成熟时间对卵母细胞孤雌发育的影响
Abolfazl Shirazi,Amin Bahiraee,Ebrahim Ahmadi et al.
Abolfazl Shirazi et al.
The aim of this study was to compare the effect of time of parthenogenetic activation (22 hr versus 27 hr after In Vitro Maturation-IVM) on in vitro development of ovine oocytes using either single (Ionomycin 5 µM for 5 min or Ethanol 7% f...
Synchronous Comparison of Mycobacterium tuberculosis Epidemiology Strains by "MIRU-VNTR" and "MIRU-VNTR and Spoligotyping" Technique [0.03%]
"MIRU-VNTR"和“MIRU-VNTR及斑点印迹法”技术同步比较分析结核杆菌流行病学株
Mehdi Jafarian,Muayed Aghali-Merza,Parissa Farnia et al.
Mehdi Jafarian et al.
Molecular epidemiology analyses are frequently used in determining epidemiology of tuberculosis. Recently, Mycobacterial Interspersed Repetitive Unit Variable Number Tandem Repeat (MIRU-VNTR) and Spoligotyping has become an important method...
miR-155 Down Regulation by LNA Inhibitor can Reduce Cell Growth and Proliferation in PC12 Cell Line [0.03%]
LNA抑制剂下调miR-155可以减少PC12细胞系的生长和增殖
Fatemeh Kouhkan,Shaban Alizadeh,Saeid Kaviani et al.
Fatemeh Kouhkan et al.
MicroRNAs (miRNAs) are a class of small non coding regulatory RNAs that have key functions in multiple cell processes. Deregulation of these tiny miRNAs is involved in various human diseases. MiR-155 is one of the multifunctional miRNA that...
In silico Evaluation of Crosslinking Effects on Denaturant m(eq) values and ΔCp upon Protein Unfolding [0.03%]
基于计算机模拟的交联作用对变性剂m(eq)值及蛋白质去折叠过程中ΔCp的影响研究
Maryam Hamzeh-Mivehroud,Ali Akbar Alizade,Monire Ahmadifar et al.
Maryam Hamzeh-Mivehroud et al.
Important thermodynamic parameters including denaturant equilibrium m values (m(eq)) and heat capacity changes (ΔCp) can be predicted based on changes in Solvent Accessible Surface Area (SASA) upon unfolding. Crosslinks such as disulfide b...
Lack of Association between Tumor Necrosis Factor-alpha -308 G/A Polymorphism and Risk of Developing Late-Onset Alzheimer's Disease in an Iranian Population [0.03%]
TNF-α-308G/A多态性与伊朗人群晚发性阿尔茨海默病发病风险无关
Mehdi Manoochehri,Koorosh Kamali,Mehdi Rahgozar et al.
Mehdi Manoochehri et al.
Late-onset Alzheimer's Disease (LOAD) is a neurodegenerative disorder and the most common form of dementia affecting people over 65 years old. Alzheimer's disease is a complex disease with multi-factorial etiology. Inflammation has been app...
Human Tissue Plasminogen Activator Expression in Escherichia coli using Cytoplasmic and Periplasmic Cumulative Power [0.03%]
利用细胞内和周质累积力表达人组织型纤溶酶原激活剂杂合体蛋白质的重组工程菌及其诱导表达方法
Keivan Majidzadeh-A,Fereidoun Mahboudi,Mahdi Hemayatkar et al.
Keivan Majidzadeh-A et al.
Tissue plasminogen activator (tPA) is a serine protease, which is composed of five distinct structural domains with 17 disulfide bonds, representing a model of high-disulfide proteins in human body. One of the most important limitations for...
Nephroprotective and Nitric oxide Scavenging Activity of Tubers of Momordica tuberosa in Rats [0.03%]
Momordica tuberosa薯蓣对大鼠的肾保护和一氧化氮清除活性研究
Kumar Pramod,Rao G Devala,Lakshmayya et al.
Kumar Pramod et al.
Hydroalcoholic extract (70% ethanol extract) of tubers of Momordica tuberosa Cogn. (Cucurbitaceae) was subjected to preliminary phytochemical screening by qualitative tests. Nitric oxide scavenging activity was performed by Griess reagent m...
Construction and Stable Expression of a Truncated Human Receptor Tyrosine Kinase Ror1 (Ror1-ECD) [0.03%]
截短的人类受体酪氨酸激酶rors基因的构建及稳定表达
Flora Forouzesh,Samira Shakeri Tabarian,Shaghayegh Emami et al.
Flora Forouzesh et al.
Expression of receptor tyrosine kinase Ror1 in a wide variety of cancers has emerged as a new era focusing on targeting this receptor in cancer therapy. Our preliminary results indicate the presence of a truncated transcript of Ror1 in tumo...
Production and Characterization of Mouse Monoclonal Antibodies Recognizing Human Pan-IgG Specific Conformational or Linear Epitopes [0.03%]
识别人全IgG特异性构象或线性表位的小鼠单克隆抗体的制备与鉴定
Fatemeh Hajighasemi,Jalal Khoshnoodi,Fazel Shokri
Fatemeh Hajighasemi
Background: Pan-IgG specific monoclonal antibodies (MAbs) are essential tools for assessment of humoral immunity, immune deficiency and gammopathy. In this study, four hybridoma clones producing MAbs with different specif...