Isolation and culture of human spermatogonial stem cells derived from testis biopsy [0.03%]
人睾丸活检衍生的精子干细胞的分离及体外培养
Leila Goharbakhsh,Arash Mohazzab,Sheida Salehkhou et al.
Leila Goharbakhsh et al.
Background: In cancer patients, chemo and radiotherapy can cause infertility by damaging spermatogenesis process. This process is based on self-renewal and differentiation of a rare population of the testicular cells call...
Antifungal indole and pyrrolidine-2,4-Dione derivative peptidomimetic lead design based on in silico study of bioactive Peptide families [0.03%]
基于生物活性肽家族的计算研究的抗真菌色氨酸和吡咯烷-2,4-二酮衍生物肽模拟物先导设计
Shoeib Moradi,Parisa Azerang,Vahid Khalaj et al.
Shoeib Moradi et al.
Background: The rise of opportunistic fungal infections highlights the need for development of new antimicrobial agents. Antimicrobial Peptides (AMPs) and Antifungal Peptides (AFPs) are among the agents with minimal resis...
Mohammad Azizi,Bagher Yakhchali,Abdolreza Ghamarian et al.
Mohammad Azizi et al.
Background: Infectious Bursal Disease Virus (IBDV) causes a highly immunosuppressive disease in chickens and is a pathogen of major economic importance to the poultry industry worldwide. The VP2 protein is the major host-...
Generation of a Uracil Auxotroph Strain of the Probiotic Yeast Saccharomyces boulardii as a Host for the Recombinant Protein Production [0.03%]
尿嘧啶营养缺陷型益生酵母Saccharomyces boulardii菌株的构建及其作为重组蛋白宿主表达体系的研究
Hassan Hamedi,Ali Misaghi,Mohammad Hossein Modarressi et al.
Hassan Hamedi et al.
Background: Saccharomyces boulardii (S. boulardii) is the best known probiotic yeast. The genetic engineering of this probiotic strain requires the availability of appropriate mutants to accept various gene constructs car...
Expression, Purification and Characterization of Three Overlapping Immunodominant Recombinant Fragments from Bordetella pertussis Filamentous Hemagglutinin [0.03%]
百日咳杆菌丝状血凝素三个重叠免疫优势区的表达、纯化与鉴定
Hossein Asgarian-Omran,Ali Akbar Amirzargar,Mohammad Arjmand et al.
Hossein Asgarian-Omran et al.
Background: Filamentous hemagglutinin (FHA) is one of the most important immunoprotective antigens of Bordetella pertussis (B. pertussis) and a major component of the acellular pertussis vaccine. In the present study, thr...
RORC2 gene silencing in human Th17 cells by siRNA: design and evaluation of highly efficient siRNA [0.03%]
高效沉默人Th17细胞中RORC2基因的siRNAs的设计和筛选
Mazdak Ganjalikhani Hakemi,Kamran Ghaedi,Alireza Andalib et al.
Mazdak Ganjalikhani Hakemi et al.
Background: RNA interference-based gene silencing has recently been applied as an efficient tool for functional gene analysis. RORC2 is the key transcription factor orchestrating Th17 cells differentiation, the cells that...
Constructing a Mouse Oct4 Promoter/EGFP Vector, as a Whole-Cellular Reporter to Monitor the Pluripotent State of Cells [0.03%]
构建Oct4启动子/GFP报告基因载体，作为监控细胞多能性状态的标志
Reza Ghorbani,Abdolrahman Emamzadeh,Yahya Khazaie et al.
Reza Ghorbani et al.
Background: The transcription factor Oct-4, is an important marker of undifferentiating level and a key regulating factor for maintenance of pluripotency in cells. Establishment of an Oct-4 promoter-based reporter system ...
Ali M Ardekani
Ali M Ardekani
Ali M Ardekani
Ali M Ardekani
Ali M Ardekani
Ali M Ardekani