An In silico Based Comparison of Drug Interactions in Wild and Mutant Human β-tubulin through Docking Studies [0.03%]
基于计算机的野生和突变人类β微管蛋白药物相互作用的比较研究及对接研究
Selvaakumar Chellasamy,Sudheer M M Mohammed
Selvaakumar Chellasamy
Background: Tubulin protein being the fundamental unit of microtubules is actively involved in cell division thus making them a potential anti-cancer drug target. In spite of many reported drugs against tubulin, few of th...
Development of a High-resolution Melting Analysis Method Based on SYBR Green-I for rs7216389 Locus Genotyping in Asthmatic Child Patients [0.03%]
基于SYBR Green-I的哮喘患儿rs7216389位点高分辨率熔解分析方法的建立
Zahra Vali,Abbasali Raz,Hanieh Bokharaei et al.
Zahra Vali et al.
Background: Asthma is caused by the combination of different factors. Current concepts of asthma pathogenesis emphasize on gene-environment interactions. Mega-genome scanning projects revealed that different Single Nucleo...
Computational Survey of FHIT, A Putative Human Tumor Suppressor, Truncates Structure [0.03%]
FHIT截短结构的计算分析(人类肿瘤抑制因子)
Ameneh Eslamparast,Mohammad Hossein Ghahremani,Soroush Sardari
Ameneh Eslamparast
Background: Fragile Histidine Triad protein (FHIT), as a known tumor suppressor protein, has been proposed to play crucial role in inhibiting p53 degradation by MDM2. Studies have confirmed FHIT interaction with p53 or MD...
Shahin Akhondzadeh
Shahin Akhondzadeh
Fine Structures of the Oocyte in Relation to Serum, Follicular Fluid Steroid Hormones and IGF-I in the Ovulatory-Sized Follicles in One-Humped Camel (Camelus dromedarius) [0.03%]
与单峰骆驼（Camelus dromedarius）排卵大小卵泡血清、卵泡液类固醇激素和IGF-I有关的卵母细胞精细结构的关系研究
Mojtaba Kafi,Seyed Fakhroddin Mesbah,Najmeh Davoodian et al.
Mojtaba Kafi et al.
Background: The following study was carried out to determine the ultrastructural features of the oocyte of the ovulatory-sized follicles in relation to concentrations of steroids and IGF-I in the Follicular Fluid (FF) and...
Downregulation of MMP2 and Bcl-2 in Adipose Derived Stem Cells (ASCs) following Transfection with IP-10 Gene [0.03%]
IP-10基因转染诱导的脂肪来源干细胞中基质金属蛋白酶2和Bcl-2表达下调的研究
Mahboobeh Razmkhah,Mansooreh Jaberipour,Abbas Ghaderi
Mahboobeh Razmkhah
Background: Mesenchymal Stem Cells (MSCs) are recently introduced as novel immunological gene carriers for treatment of cancer. It is believed that balance between the expression of angiogenic and anti-angiogenic factors,...
Messenger RNA Expression Patterns of Neurotrophins during Transdifferentiation of Stem Cells from Human-Exfoliated Deciduous Teeth into Neural-like Cells [0.03%]
人乳牙干细胞向神经样细胞转分化过程中神经营养因子的表达模式研究
Abolghasem Esmaeili,Sedigheh Alifarja,Nosrat Nourbakhsh et al.
Abolghasem Esmaeili et al.
Background: Stem cells from Human Exfoliated Deciduous teeth (SHED) have the capability to differentiate into neural cells. Neurotrophins including Nerve Growth Factor (NGF), Brain-Derived Neurotrophic Factor (BDNF), neur...
Evaluation of the Effect of miR-26b Up-Regulation on HbF Expression in Erythroleukemic K-562 Cell Line [0.03%]
miR-26b上调对红白血病K-562细胞株HbF表达的影响分析
Sadegh Alijani,Shaban Alizadeh,Ahmad Kazemi et al.
Sadegh Alijani et al.
Background: The major hemoglobin in the fetus is hemoglobin F (HbF) (α2γ2), whereas in adult humans, hemoglobin A (α2β2) is predominately expressed. Several studies have indicated that expression of the HbF subunit γ...
Fourier transform infrared spectroscopy: a potential technique for noninvasive detection of spermatogenesis [0.03%]
傅立叶变换红外光谱法在非侵入性检测生精功能障碍中的应用潜力研究
Kambiz Gilany,Roudabeh Sadat Moazeni Pouracil,Mohammad Reza Sadeghi
Kambiz Gilany
Background: The seminal plasma is an excellent source for noninvasive detection of spermatogenesis. The seminal plasma of normospermic and azoospermic men has been analyzed for detection of spermatogenesis. ...
Assessment of different permeabilization methods of minimizing damage to the adherent cells for detection of intracellular RNA by flow cytometry [0.03%]
评估不同的透化方法以最小化对贴壁细胞的损伤从而通过流式细胞术检测胞内RNA
Zahra Amidzadeh,Abbas Behzad Behbahani,Nasrollah Erfani et al.
Zahra Amidzadeh et al.
Background: Various fixation and permeabilization techniques have been developed for detection of intracellular antigens by flow cytometry; however, there are few studies using flow cytometry to detect the frequency of in...