The Potential of Brittle Star Extracted Polysaccharide in Promoting Apoptosis via Intrinsic Signaling Pathway [0.03%]
海星多糖通过线粒体介导的信号途径促进细胞凋亡的潜能研究
Javad Baharara,Elaheh Amini
Javad Baharara
Background: Anti-cancer potential of marine natural products such as polysaccharides represented therapeutic potential in oncological researches. In this study, total polysaccharide from brittle star [Ophiocoma erinaceus ...
Preliminary Assessment of Various Additives on the Specific Reactivity of Anti- rHBsAg Monoclonal Antibodies [0.03%]
各种添加剂对抗乙肝表面抗原抗体特异活性的初步评价研究
Yaghoub Yazdani,Saeed Mohammadi,Mehdi Yousefi et al.
Yaghoub Yazdani et al.
Background: Antibodies have a wide application in diagnosis and treatment. In order to maintain optimal stability of various functional parts of antibodies such as antigen binding sites, several approaches have been sugge...
A Comprehensive Review of Clinical Trials on EGFR Inhibitors Such as Cetuximab and Panitumumab as Monotherapy and in Combination for Treatment of Metastatic Colorectal Cancer [0.03%]
西妥昔单抗和帕尼单抗等表皮生长因子受体抑制剂单药及其联合治疗转移性结直肠癌的临床试验综合分析
Mohammad Hossein Yazdi,Mohammad Ali Faramarzi,Shekoufeh Nikfar et al.
Mohammad Hossein Yazdi et al.
Metastatic colorectal cancer is the fourth most common cause of death due to cancer after those of lung, stomach, and liver. Anti epidermal growth factor receptor drugs as a targeting therapy seem to be good candidates for curing metastatic...
Shahin Akhondzadeh
Shahin Akhondzadeh
An Association Study on IL16 Gene Polymorphisms with the Risk of Sporadic Alzheimer's Disease [0.03%]
IL16基因多态性与散发性阿尔茨海默病发病风险的关联研究
Tayyebeh Khoshbakht,Mohsen Soosanabadi,Maryam Neishaboury et al.
Tayyebeh Khoshbakht et al.
Background: Interleukin-16 (IL-16) is an important regulator of T cell activation and was reported to act as a chemoattractant agent. There are evidences that IL16 can control the neuroinflammatory processes in Alzheimer'...
In silico Evaluation of Nonsynonymous Single Nucleotide Polymorphisms in the ADIPOQ Gene Associated with Diabetes, Obesity, and Inflammation [0.03%]
ADIPORQ基因的非同义单核苷酸多态性与糖尿病、肥胖和炎症的关联的计算机评估方法
A Narayana Swamy,Harika Valasala,Sreenivasulu Kamma
A Narayana Swamy
Background: The human ADIPOQ gene encodes adiponectin protein hormone, which is involved in regulating glucose levels as well as fatty acid breakdown. It is exclusively produced by adipose tissue and abundantly present in...
Inhibition of Coenzyme Qs Accumulation in Engineered Escherichia coli by High Concentration of Farnesyl Diphosphate [0.03%]
法尼基二磷酸高浓度下工程菌株的大分子辅酶Q积累抑制效应
Mojtaba Samoudi,Negar Omid Yeganeh,Hossein Shahbani Zahiri et al.
Mojtaba Samoudi et al.
Background: Coenzyme Q 10 (CoQ 10 ) is an isoprenoid component used widely in nutraceutical industries. Farnesyl diphosphate synthase (FPPS) is a responsible enzyme for biosynthesis of farnesyl diphosphate (FPP), a key pr...
Retinoic Acid as the Stimulating Factor for Differentiation of Wharton's Jelly-Mesenchymal Stem Cells into Hepatocyte-like Cells [0.03%]
视黄酸诱导Wharton氏胶间充质干细胞向肝细胞分化的一种分化因子
Keywan Mortezaee,Bagher Minaii,Fatemeh Sabbaghziarani et al.
Keywan Mortezaee et al.
Background: Wharton's Jelly-Mesenchymal Stem Cells (WJ-MSCs) are pluripotent cells with differentiation capability into most cell lineages. The aim of the current work was to examine the role of Retinoic Acid (RA) in diff...
Expression of Recombinant Human Insulin-like Growth Factor Type 1 (rhIGF-1) in Escherichia coli [0.03%]
人重组胰岛素样生长因子Ⅰ(rhIGF-1)在大肠杆菌中的表达
Hamidreza Iranpoor,Eskandar Omidinia,Venus Vatankhah et al.
Hamidreza Iranpoor et al.
Background: Human insulin-like growth factor type 1 (hIGF-1) is a protein consisting of 70 amino acids (MW=7.6 kDa) and mainly synthesized by liver. Mecasermin (Trade name INCRELEX) is the synthetic form of the protein wh...
Atefeh Biabangard Zak,Masoud Golalipour,Gholamreza Hadadchi
Atefeh Biabangard Zak
Background: Microdeletions of the Y chromosome are one of the most frequent genetic causes of spermatogenic failure in infertile men. But their role in gaining weight is unclear. The present study investigated the possibl...