The Role of M2000 as an Anti-inflammatory Agent in Toll-Like Receptor 2/microRNA-155 Pathway [0.03%]
M2000通过 toll小分子干扰rna-155信号通路抑制tlr2介导的炎症反应的作用及机制研究
Fatemeh Pourgholi,Mahsa Hajivalili,Rasoul Razavi et al.
Fatemeh Pourgholi et al.
Background: M2000 is a newly designed and safe Non-Steroidal Anti-Inflammatory Drug (NSAID). The aim of this study was to assess the effects of M2000 on expression levels of Suppressor of Cytokine Signaling-1 (SOCS-1) and...
The Effects of Berberine and Palmatine on Efflux Pumps Inhibition with Different Gene Patterns in Pseudomonas aeruginosa Isolated from Burn Infections [0.03%]
小檗碱和棕榈碱对烧伤感染铜绿假单胞菌外排泵抑制作用的差异性研究
Seyed Sajjad Aghayan,Hamidreza Kalalian Mogadam,Mozhgan Fazli et al.
Seyed Sajjad Aghayan et al.
Background: Related Multidrug Resistance (MDR) to efflux pumps is a significant problem in treating infections caused by Pseudomonas aeruginosa (P. aeruginosa). Plant compounds have been identified as Pump Inhibitors (EPI...
Shahin Akhondzadeh
Shahin Akhondzadeh
Lack of Association between Interleukin-12 Gene Polymorphisms and Recurrent Aphthous Stomatitis [0.03%]
白细胞介素12基因多态性与复发性阿弗他溃疡无关
Isaac Firouze Moqadam,Shamsolmoulouk Najafi,Mahsa Mohammadzadeh et al.
Isaac Firouze Moqadam et al.
Development of a High-Resolution Melting Analysis Method for CYP2C19*17 Genotyping in Healthy Volunteers [0.03%]
健康受试者CYP2C19*17基因分型高分辨率熔解曲线分析方法的建立
Zahra Ghasemi,Mehrdad Hashemi,Mahsa Ejabati et al.
Zahra Ghasemi et al.
Background: Genetic polymorphisms of drug metabolisms by cytochrome P450 (P450s) could affect drug response, attracting particular interest in the pharmacogenetics. Due to the importance of CYP2C19* 17 allele and its capa...
Preliminary Study on Cost-Effective L-Tryptophan Production from Indole and L-Serine by E. coli Cells [0.03%]
大肠杆菌细胞利用吲哚和L-丝氨酸低成本高效生产L-色氨酸的初步研究
Tahereh Sadeghiyan-Rizi,Jamshid Fooladi,Sima Sadrai
Tahereh Sadeghiyan-Rizi
Background: L-tryptophan is used widespread in the pharmaceutical industry. The majority of L-Trp production depends on microbial processes that produce L-tryptophan from indole and L-serine. These processes are very cost...
Evaluation of Recombinant Human Growth Hormone Secretion in E. coli using the L-asparaginase II Signal Peptide [0.03%]
大肠杆菌L-天冬氨酶II信号肽促进重组人生长激素分泌表达
Mozhdeh Zamani,Navid Nezafat,Younes Ghasemi
Mozhdeh Zamani
Background: In the recent years, there has been an increasing interest in secretory production of recombinant proteins, due to its various advantages compared with intracellular expression. Signal peptides play a critical...
Cloning and Expression of Soluble Recombinant HIV-1 CRF35 Protease-HP Thioredoxin Fusion Protein [0.03%]
HIV-1 CRF35耐药株protease-重组谷胱甘肽S-转移酶融合蛋白的克隆及可溶性表达
Asaad Azarnezhad,Zohreh Sharifi,Rahmatollah Seyedabadi et al.
Asaad Azarnezhad et al.
Background: As a drug target and an antigenic agent, HIV-1 protease (HIV-1 PR) is at the center of attention for designing anti-AIDS inhibitors and diagnostic tests. In previous studies, the production of the recombinant ...
Novel Combinations of Synthesized ZnO NPs and Ceftazidime: Evaluation of their Activity against Standards and New Clinically Isolated Pseudomonas aeruginosa [0.03%]
新型合成ZnO纳米颗粒与 ceftazidime 组合对抗标准和新分离的铜绿假单胞菌株的活性评估
Elham Isaei,Shahla Mansouri,Fereshteh Mohammadi et al.
Elham Isaei et al.
Background: Antibiotic resistant bacteria can be considered as a main problem in infection management. Zinc oxide nanoparticles (ZnO NPs), individually or in combination with antibiotics, can be considered as good candida...
Exogenous Secreted Frizzled-Related Protein-4 Modulates Steroidogenesis of Rat Granulosa Cells through Wnt/β-catenin and PI3K/AKT Signaling Pathways [0.03%]
外源性分泌型frizzled相关蛋白4通过Wnt/β-catenin和PI3K/Akt信号通路调控大鼠颗粒细胞类固醇激素生成
Ghamartaj Hossein,Manijeh Khanmohammadi,Parisa Sahranavard Fard et al.
Ghamartaj Hossein et al.
Background: It has been reported that secreted frizzled-related protein-4 known as an antagonist of Wnt signaling pathway plays a role in luteinization process of rodent granulosa cells. The purpose of this study was twof...