Enhancing Stability of Destabilized Green Fluorescent Protein Using Chimeric mRNA Containing Human Beta-Globin 5' and 3' Untranslated Regions [0.03%]
利用人β-珠蛋白的5'和3'非翻译区嵌合mRNA增强去稳定型绿色荧光蛋白的稳定性
Setare Adibzadeh,Majid Fardaei,Mohammad Ali Takhshid et al.
Setare Adibzadeh et al.
Background: In spite of recent progress in mRNA technologies and their potential applications for treatment of human diseases, problems such as the transient nature of mRNA limit the stability of gene up-regulation and, t...
Prediction of RNA- and DNA-Binding Proteins Using Various Machine Learning Classifiers [0.03%]
基于各种机器学习分类器的RNA和DNA结合蛋白预测
Mehdi Poursheikhali Asghari,Parviz Abdolmaleki
Mehdi Poursheikhali Asghari
Background: Nucleic acid-binding proteins play major roles in different biological processes, such as transcription, splicing and translation. Therefore, the nucleic acid-binding function prediction of proteins is a step ...
Identification of Potential Lead Molecules for Zika Envelope Protein from In Silico Perspective [0.03%]
基于计算机辅助的Zika病毒包膜蛋白潜在小分子抑制剂的研究
Selvaa Kumar Chellasamy,Shine Devarajan
Selvaa Kumar Chellasamy
Background: Zika virus is the family member of flavivirus with no reported clinically approved drugs or vaccines in the market till date. This virus is spread by Aedes mosquitoes, and can also be transmitted through sexua...
Expression and Activity of Platelet Endothelial Nitric Oxide Synthase Are Decreased in Patients with Coronary Thrombosis and Stenosis [0.03%]
冠状血栓和狭窄患者血小板内皮型一氧化氮合酶的表达及其活性降低
Zahra Emami,Alireza Mesbah Namin,Javad Kojuri et al.
Zahra Emami et al.
Background: Nitric Oxide (NO) which is synthesized by endothelial Nitric Oxide Synthase (eNOS) in both vascular tissues and platelets plays an important role as a protective mediator in the cardiovascular system. It modul...
Development and Comparison of In-house Line Probe Assay (LiPA) and SYBR Green Real-time PCR Regarding the Detection of Periodontal Pathogens [0.03%]
基于SYBR Green的实时PCR与牙周病原菌检测线探针法（LiPA）的建立及比较
Mohammad Soleimani,Mohammad Reza Zolfaghari
Mohammad Soleimani
Background: Periodontal disease, which can become a chronic condition, is an inflammatory disease that upsets the soft and hard structures supporting the teeth. The aim of the present study was to design and develop an in...
Characterization of Monoclonal and Polyclonal Antibodies Recognizing Prostate Specific Antigen: Implication for Design of a Sandwich ELISA [0.03%]
用于设计夹心酶联免疫吸附测定的单克隆抗体和多克隆抗体识别前列腺特异性抗原的特征分析
Sahar Raoofi Mohseni,Forough Golsaz-Shirazi,Mostafa Hosseini et al.
Sahar Raoofi Mohseni et al.
Background: Prostate cancer is the second most common cancer in men. Prostate-Specific Antigen (PSA) is a tumor-associated glycoprotein with enzymatic activity which is secreted by the prostate gland. Following entry to t...
The Effect of TAX-1 Gene of Human T-cell Leukemia Virus Type-1 on the Expression of CCR5 in K562 Cell Line [0.03%]
人T细胞白血病病毒Ⅰ型TAX基因对K562细胞系CCR5表达的影响
Nasrin Haghnazari Sadaghiani,Lila Pirayeshfard,Afsaneh Aghaie et al.
Nasrin Haghnazari Sadaghiani et al.
Background: Tax-1 protein of Human T-cell Leukemia Virus type 1(HTLV-1) serves as a key transcriptional regulatory gene product and has a crucial role in transactivating genes of infected cells by employing their transcri...
Statistical Optimization of Process Parameters by Central Composite Design (CCD) for an Enhanced Production of L-asparaginase by Myroides gitamensis BSH-3, a Novel Species [0.03%]
中心组合设计（CCD）优化新种Myroides gitamensis BSH-3产生L-天冬酰胺酶的高效生产工艺参数
Vssl Prasad Talluri,Sri Santhi Lanka,V Rajagopal Saladi
Vssl Prasad Talluri
Background: The present study focused on the production of L-asparaginase using Solid State Fermentation (SSF) by Myroides gitamensis. Methods: ...
A Multidisciplinary Study to Evaluate the Anti-quorum Sensing Ability of Phyto-compounds in Ruellia patula Jacq [0.03%]
罗勒香蜂草中植物化合物的抗群体感应能力的多学科研究评估
P Chemmugil,Ptv Lakshmi,A Annamalai
P Chemmugil
Background: Staphylococcus aureus (S. aureus) causing numerous diseases in humans, have become resistant to antibiotics, hence, urging the need for alternative medicines. ...
The Anti-cancer Effects of Capparis spinosa Hydroalcoholic Extract [0.03%]
Capparis spinosa羟乙醇提取物的抗肿瘤作用
Yasaman Moghadamnia,Seydeh Narges Mousavi Kani,Maryam Ghasemi-Kasman et al.
Yasaman Moghadamnia et al.
Background: Recently, due to the steep increase in cancer lethality statistics, pharmaceutical societies seek approaches for designing drugs with higher efficiency and lower expenses. Plant-based drugs have therefore gain...