Evaluation of Immune Response and Protection Induced by V-ATPase Subunit F as DNA Vaccine Against Leishmania tropica (LCED Syrian 01) After Detection and Sequencing [0.03%]
检测和测序后评估V-ATP酶亚基F作为DNA疫苗针对Leishmania tropica（LCED叙利亚01）免疫反应及保护作用的效果
Amira Orabi,Mohammad Maarouf,Mustafa Alammori
Amira Orabi
Background: Leishmaniasis is one of the major emerging health problems worldwide and Leishmania tropica (L. tropica) is most prevalent in the Middle East due to conflict and environmental factors, and there is no effectiv...
Pooria Gill,Arash Hadian Amree
Pooria Gill
In recent decades, different methods have been introduced for the genotyping of Single Nucleotide Polymorphisms (SNPs) and mutations in nucleic acid sequences. These methods have several applications ranging from agriculture to medicine. Th...
Fatemeh Ghaemimanesh
Fatemeh Ghaemimanesh
Importance of Fluctuating Amino Acid Residues in Folding and Binding of Proteins [0.03%]
蛋白质折叠和结合中波动氨基酸残基的重要性
Renganathan Senthil,Singaravelu Usha,Konda Mani Saravanan
Renganathan Senthil
Background: Conformational flexibility of proteins remains as one of the major events in protein-protein/DNA/ligand/small molecule binding to achieve its biological function in the cell. The availability of high-resolutio...
Integrity and Quantity Evaluation of Plasma Cell-Free DNA in Triple Negative Breast Cancer [0.03%]
三阴性乳腺癌血浆游离DNA的完整性和含量评估
Mahdieh Salimi,Somayeh Sedaghati Burkhani
Mahdieh Salimi
Background: Triple-Negative Breast Cancer (TNBC) is a subtype of breast cancer that lacks expression of the estrogen and progesterone receptor and does not overex-press human epidermal growth factor 2 receptor protein. TN...
Interleukin 10 and Transforming Growth Factor Beta Polymorphisms as Risk Factors for Kawasaki Disease: A Case-Control Study and Meta-Analysis [0.03%]
白细胞介素10和转化生长因子β基因多态性与川崎病发病相关的风险因素：病例对照研究及荟萃分析
Farzaneh Rahmani,Vahid Ziaee,Raheleh Assari et al.
Farzaneh Rahmani et al.
Background: Alteration in serum expression of Transforming Growth Factor-beta (TGF-β) and IL-10 have been suggested to play a role in the pathogenesis of Kawasaki Disease (KD). Inconsistent reports exist on the associati...
Effect of Sodium Butyrate on LHX1 mRNA Expression as a Transcription Factor of HDAC8 in Human Colorectal Cancer Cell Lines [0.03%]
丁酸钠对HDAC8转录因子LHX1在人结直肠癌细胞系中表达的影响
Mahsa Ghiaghi,Flora Forouzesh,Hamzeh Rahimi
Mahsa Ghiaghi
Background: LHX1 is an important transcription factor for the HDAC8 gene. The aim of this study was to investigate the effect of Sodium Butyrate (SB), as a histone deacetylase inhibitor, on the expression of LHX1 gene in ...
Menstrual Blood Stem Cell Transplantation in Mice Model of Acute Liver Failure: Does Gender of Recipient Affect the Outcome? [0.03%]
雌性小鼠性别对月经血源干细胞移植治疗急性肝功能衰竭疗效的影响？
Mina Fathi-Kazerooni,Gholamreza Tavoosidana
Mina Fathi-Kazerooni
Background: There exists a dramatic rise in liver failure and numerous patients undergo liver transplant for life-saving reasons annually. Introducing alternatives to allo-graft transplantation is necessary due to present...
A Metabolomic Study to Identify Potential Tissue Biomarkers for Indomethacin-Induced Gastric Ulcer in Rats [0.03%]
代谢组学研究寻找吲哚美辛致大鼠胃溃疡潜在组织生物标志物
Reyhaneh Farrokhi Yekta,Nasrin Amiri-Dashatan,Mehdi Koushki et al.
Reyhaneh Farrokhi Yekta et al.
Background: Gastric Ulcer (GU) is the most prevalent gastrointestinal disorder induced by various factors and Non-Steroid Anti-Inflammatory Drugs (NSAIDs) as one of the most common reasons. Due to the absence of appropria...
G2 Dendrimer as a Carrier Can Enhance Immune Responses Against HCV-NS3 Protein in BALB/c Mice [0.03%]
星型聚已内酯二聚体G2作为载体制备塞曲司特纳米粒及其药代动力学研究
Foozieh Javadi,Pooneh Rahimi,Mohammad Hossien Modarresi et al.
Foozieh Javadi et al.
Background: Hepatitis C virus (HCV) infection is a major issue of public health. It seems of paramount importance to find an effective vaccine against HCV infection. The best vaccine candidate should induce robust cellula...