Expression and Characterization of Two DNA Constructs Derived from HIV-1-vif in Escherichia coli and Mammalian Cells [0.03%]
HIV-1-vif衍生的两种DNA构建体在大肠杆菌和哺乳动物细胞中的表达及鉴定
Fatemeh Zamani,Azam Bolhassani,Sepideh Shahbazi et al.
Fatemeh Zamani et al.
Background: Acquired immunodeficiency syndrome (HIV/AIDS) is still a major global concern and no effective therapeutic vaccine has been produced to prevent the problem. Among HIV-1 proteins, vif as a basic cytoplasmic pro...
Designing a Strategy for pH Control to Improve CHO Cell Productivity in Bioreactor [0.03%]
设计用于提高生物反应器中CHO细胞产量的PH控制策略的方法
Zohreh Ahleboot,Mahdi Khorshidtalab,Paria Motahari et al.
Zohreh Ahleboot et al.
Background: Drastic pH drop is a common consequence of scaling up a mammalian cell culture process, where it may affect the final performance of cell culture. Although CO2 sparging and base addition are used as common app...
The Impact of Nrf2 Silencing on Nrf2-PD-L1 Axis to Overcome Oxaliplatin Resistance and Migration in Colon Cancer Cells [0.03%]
Nrf2沉默对Nrf2-PD-L1轴的作用及对奥沙利铂耐药和结肠癌细胞迁移的克服作用分析
Zahra Payandeh,Abbas Pirpour Tazehkand,Behzad Mansoori et al.
Zahra Payandeh et al.
Background: Nuclear factor-erythroid 2-related factor 2 (Nrf2) plays a key role in promoting chemoresistance in various cancers. PD-L1 is one of the downstream targets of the Nrf2 signaling pathway. This molecule has some...
The Novel Drug Discovery to Combat COVID-19 by Repressing Important Virus Proteins Involved in Pathogenesis Using Medicinal Herbal Compounds [0.03%]
利用药用植物化合物抑制重要病毒蛋白以对抗COVID-19的新药发现
Samira Mahmoudi,Negar Balmeh,Niloofar Mohammadi et al.
Samira Mahmoudi et al.
Background: The cause of COVID-19 global pandemic is SARS-CoV-2. Given the outbreak of this disease, it is so important to find a treatment. One strategy to cope with COVID-19 is to use the active ingredients of medicinal...
Medical Biotechnology in the Service of Coronavirus Vaccine Discovery and Production [0.03%]
助力新型冠状病毒疫苗发现与生产的医学生物技术
Shahin Akhondzadeh,Ahmad Shamabadi
Shahin Akhondzadeh
The Effect of Silver Nanoparticles on Pyocyanin Production of Pseudomonas aeruginosa Isolated From Clinical Specimens [0.03%]
银纳米颗粒对临床标本分离铜绿假单胞菌产绿脓素的影响
Mahboobeh Najafi,Mahboobeh Nakhaei Moghaddam,Ehsan Yousefi
Mahboobeh Najafi
Background: Pseudomonas aeruginosa (P. aeruginosa) is an opportunistic pathogen causing a wide range of human infections. The organism is resistant to a wide range of antibiotics. The purpose of this study was to investig...
Designing Two Synthetic Constructs for Real Time PCR Detection of Francisella tularensis and Ebola Virus [0.03%]
用于实时PCR检测土拉菌和埃博拉病毒的两种合成体系的设计
Mohammadjavad Dehghan Esmat Abadi,Hesam Motalebzadeh,Mahmoud Barati et al.
Mohammadjavad Dehghan Esmat Abadi et al.
Background: Generally, timely diagnosis of micro-organisms is very important to prevent many diseases. Many methods can detect micro-organisms like culture-based methods and molecular methods. The molecular methods are us...
Benchmarking Datasets from Malaria Cytotoxic T-cell Epitopes Using Machine Learning Approach [0.03%]
基于机器学习的疟疾细胞毒性T细胞表位基准数据集评测
Rama Adiga
Rama Adiga
Background: Epitope prediction remains a major challenge in malaria due to the unique parasite biology, in addition to rapidly evolving parasite sequence variation in Plasmodium species. Although several models for epitop...
The Effect of Sodium Selenite on Expression of Mitochondrial Transcription Factor A during In Vitro Maturation of Mouse Oocyte [0.03%]
钠硒ite对小鼠卵母细胞体外成熟过程中线粒体转录因子a表达的影响
Tina Moshaashaee,Saeed Zavareh,Shahram Pourbeiranvand et al.
Tina Moshaashaee et al.
Background: The aim of the present study was to investigate the effect of Sodium Selenite (SS) supplemented media on oocyte maturation, expression of mitochondrial transcription factor A (TFAM) and embryo quality. ...
Developmental Toxicity of the Neural Tube Induced by Titanium Dioxide Nanoparticles in Mouse Embryos [0.03%]
纳米二氧化钛颗粒诱导的小鼠胚胎神经管发育毒性研究
Nahid Mohamadzadeh,Masoumeh Zirak Javanmard,Mojtaba Karimipour et al.
Nahid Mohamadzadeh et al.
Background: This study investigated the potential effects of Titanium dioxide nanoparticles (Tio2NPs) followed by maternal gavage on fetal development and neural tube formation during pregnancy in mice. ...