Fabrication of Calcium Sulfate Coated Selenium Nanoparticles and Corresponding In-Vitro Cytotoxicity Effects Against 4T1 Breast Cancer Cell Line [0.03%]
硫酸钙硒纳米粒子的制备及对4T1乳腺癌细胞系的体外毒性效应研究
Elnaz Faghfuri,Ramak Ajideh,Faranak Shahverdi et al.
Elnaz Faghfuri et al.
Background: The inhibitory effect of selenium nanoparticles (SeNPs) on cancer cells has been reported in many studies. In this study, the purpose was to compare the in vitro effects of SeNPs and calcium sulfate coated sel...
Production of PEGylated GCSF from Non-classical Inclusion Bodies Expressed in Escherichia coli [0.03%]
大肠杆菌非经典包涵体中PEG化GCSF的生产
Nguyen Thi My Trinh,Tran Linh Thuoc,Dang Thi Phuong Thao
Nguyen Thi My Trinh
Background: The recombinant human granulocyte colony stimulating factor conjugated with polyethylene glycol (PEGylated GCSF) has currently been used as an efficient drug for the treatment of neutropenia caused by chemothe...
A Cross-Sectional Study for Evaluation of KRAS and BRAF Mutations by Reverse Dot Blot, PCR-RFLP, and Allele-Specific PCR Methods Among Patients with Colorectal Cancer [0.03%]
结直肠癌患者KRAS和BRAF基因突变状态的逆转点杂交、PCR-RFLP及等位基因特异性PCR方法学评价横断面研究
Fatemeh Sheikhsofla,Behzad Poopak,Sajjad Firuzyar et al.
Fatemeh Sheikhsofla et al.
Background: KRAS and BRAF genes are the biomarkers in Colorectal Cancer (CRC) which play prognostic and predictive roles in CRC treatment. Nowadays, the selection of rapid and available methods for studying KRAS and BRAF ...
Apoptosis Induction with Combined Use of Cisplatin and Fisetin in Cisplatin-Resistant Ovarian Cancer Cells (A2780) [0.03%]
联合使用顺铂和山柰酚对顺铂耐药卵巢癌细胞(A2780)诱导凋亡的作用
Samira Jafarzadeh,Javad Baharara,Maryam Tehranipour
Samira Jafarzadeh
Background: Ovarian cancer is the leading cause of death caused by genital cancers. One of the most common treatments for this type of cancer is chemotherapy by cisplatin, which induces apoptosis in cancer cells. Apoptosi...
Integrating Psychiatry and Medical Biotechnology as a Way to Achieve Scientific, Precision, and Personalized Psychiatry [0.03%]
精神病学和医学生物技术的融合——实现科学、精确、个性化精神医学的一种途径
Ahmad Shamabadi,Alireza Hasanzadeh,Shahin Akhondzadeh
Ahmad Shamabadi
Besides concerns about the increasing prevalence of psychiatric disorders and the significant burdens and costs, there are concerns about its validity. The dilemma of validity went so far that studies described the diagnoses in psychiatry a...
ZHER2 Affibody as a Good Candidate for Detection of Metastatic Prostate Cancer [0.03%]
用于检测转移性前列腺癌的ZHER2:Afc蛋白作为良好的候选物
Mahboobeh Nazari,Ramin Radmanesh
Mahboobeh Nazari
Association of a Functional Single Nucleotide Polymorphism (rs874040) in the RBPJ Gene with Susceptibility to Rheumatoid Arthritis in Iranian Population [0.03%]
RBPJ基因功能性单核苷酸多态性（rs874040）与伊朗人群类风湿关节炎易感性的关联研究
Mansour Salesi,Mahdieh Oboodiyat,Rasoul Salehi et al.
Mansour Salesi et al.
Background: Rheumatoid Arthritis (RA) is a progressive, heterogeneous, and common multifactorial autoimmune disease. Several Genome-Wide Association Studies (GWASs) have revealed more than 100 risk loci for RA. One of the...
An Integrated Bioinformatics Analysis of the Potential Regulatory Effects of miR-21 on T-cell Related Target Genes in Multiple Sclerosis [0.03%]
miR-21潜在调节作用的综合生物信息学分析在多发性硬化T细胞相关靶基因中的研究
Mostafa Manian,Ehsan Sohrabi,Nahid Eskandari et al.
Mostafa Manian et al.
Background: Overexpression of miR-21 is a characteristic feature of patients with Multiple Sclerosis (MS) and is involved in gene regulation and the expression enhancement of pro-inflammatory factors including IFNγ and T...
Detection of Aneuploidies in Products of Conception and Neonatal Deaths in Iranian Patients Using the Multiplex Ligation-Dependent Probe Amplification (MLPA) [0.03%]
应用多重连接依赖探针扩增技术检测伊朗患者胚胎和新生儿死亡标本中的非整倍体异常
Sara Khorami Sarvestani,Maryam Rafati,Haleh Soltanghoraee et al.
Sara Khorami Sarvestani et al.
Background: Around 70% of all pregnancies (Including 15% of clinically-recognized ones) are lost due to various fetal or maternal disorders. Chromosomal aneuploidies are among the most common causes of pregnancy loss. Sta...
Determining the Specific Activity of Anti-Rabies Sera and Immunoglobulin Using Atomic Force Microscopy of Cell Cultures [0.03%]
采用原子力显微镜检测细胞培养测定抗狂犬病血清和免疫球蛋白的特异活性
Sergey V Generalov,Pavel S Erokhin,Oleg S Kuznetsov et al.
Sergey V Generalov et al.
Background: Mouse neutralization test is widely used to determine the level of anti-rabies antibodies, but it is labor-intensive and time consuming. Alternative methods for determining the neutralizing activity of anti-ra...