Impact of Genotropin on Oxidative Stress, Glutamate, and Nitric Oxide Pathways in a Rat Model of Peripheral Neuropathy [0.03%]
基因疗法对周围神经病大鼠模型氧化应激、谷氨酸和一氧化氮通路的影响
Sepideh Saffarpour,Arash Mehraz,Pargol Sadeghi Tehran et al.
Sepideh Saffarpour et al.
Introduction: Genotropin, a recombinant human growth hormone (GH), has been proposed as a potential repositioning drug to treat neurological disorders. However, its efficacy in managing neuropathic pain remains unclear. T...
Histone Deacetylase Class IIb Inhibition Improves Amyloid-β-induced Learning and Memory Deficits in Male Rats [0.03%]
组蛋白去乙酰酶IIb抑制剂改善雄性大鼠淀粉样蛋白诱发的学习和记忆缺损
Zahra Mansouri,Fereshteh Motamedi,Fariba Khodagholi et al.
Zahra Mansouri et al.
Introduction: Alzheimer's disease (AD) is a neurodegenerative disease associated with progressive impairment of cognitive function. The primary pathological features of AD include aggregation of amyloid-β (Aβ) and hyper...
Vitis Vinifera L. Flavones Preserve Mitophagy in the Amyloid-beta 1-42-induced Model of Alzheimer's Disease Neurodegeneration [0.03%]
葡萄霜霉威菌 flavones 对淀粉样蛋白 β1-42 引起的阿尔茨海默病神经退行性病变中线粒体自噬的保护作用
Peng Zhang,Hui Xiao
Peng Zhang
Introduction: Alzheimer's disease (AD) is a prevalent neurodegenerative disorder characterized by amyloid-beta (Aβ) accumulation, leading to inflammation, oxidative stress, and impaired synaptic function. This study aime...
Vismodegib Improved Therapy of Medulloblastoma by Targeting Sonic Hedgehog Signaling Pathway on DAOY Medulloblastoma Cell Line [0.03%]
Vismodegib通过作用于DAOY髓母细胞瘤细胞系的Sonic Hedgehog信号途径改善髓母细胞瘤的治疗效果
Masume Behruzi,Mehrdad Ghorbanlou,Ronak Shabani et al.
Masume Behruzi et al.
Introduction: Targeting smoothened (SMO) has been a remarkable strategy for treating sonic hedgehog (Shh)-dependent cancers, especially medulloblastoma. GDC-0449, also known as vismodegib, is a potent SMO inhibitor with m...
Alpha-mangostin Ameliorates Apoptosis, Inflammation and Oxidative Stress in Cuprizone-induced Demyelination in C57BL/6 Mice [0.03%]
他莫西定通过抗氧化应激、抗炎和减少细胞凋亡改善Cuprizone诱导的C57BL/6小鼠脱髓鞘病变
Sara Banaeeyeh,Bibi Marjan Razavi,Hossein Hosseinzadeh
Sara Banaeeyeh
Introduction: Alpha-mangostin (α-MG), the most abundant xanthone found in Garcinia mangostana Linn, has been reported to possess potent antioxidant and anti-inflammatory properties. This study aimed to investigate the ne...
Pathways Mediating Blindsight After V1 Injury: A Systematic Review of Human and Monkey Studies [0.03%]
V1损伤后的 blindsight 机制:pathways 的系统综述（人和猴的研究）
Mohammad Reza Balali,Mohaddeseh Hosseini,Maryam Khanboloki et al.
Mohammad Reza Balali et al.
Introduction: Although damage to the visual area (V1) leads to visual impairment, some patients retain the ability to process visual information unconsciously, a phenomenon known as blindsight. This study aims to systemat...
Sural/Radial Amplitude Ratio in Healthy Adults: Influence of Anatomical and Demographic Variables [0.03%]
健康成年人腓肠神经/桡神经幅值比：解剖和人口统计学变量的影响
Fateme Hojjati,Seyed Mansour Rayegani,Ali Nazari Nodoushan et al.
Fateme Hojjati et al.
Introduction: The sural-to-radial sensory nerve action potential amplitude ratio (SRAR) can be used to diagnose peripheral axonal neuropathy. However, different studies have revealed varying lowest values for this index. ...
Short-term Efficacy of Commercial Curcumin Nanomicelle on Cognition, Oxidative Stress and Choline Esterase in Alzheimer's Disease [0.03%]
商业化姜黄素纳米胶束治疗阿尔茨海默病的短期疗效：对认知、氧化应激和胆碱酯酶的影响
Samira Kazemi,Narges Hesni Langroudi,Peyman Hasani Abharian et al.
Samira Kazemi et al.
Introduction: Alzheimer's disease (AD) is a progressive neurodegenerative disease accompanied by cognitive dysfunction. Preclinical changes can precede the onset of clinical symptoms by decades, highlighting the need for ...
Determining Pro-oxidant Antioxidant Balance in Febrile Children With and Without Seizure: A Comparative Study [0.03%]
发热伴或不伴有惊厥的儿童体内促氧化抗氧化平衡状态的比较研究
Mohammad Salari Zare,Mehran Mir,Saeideh Sadat Shobeiri et al.
Mohammad Salari Zare et al.
Introduction: A benign condition known as a febrile seizure (FS) occurs between the ages of six and 60 months when the patient has a fever of at least 38 °C, is not suffering from a central nervous system (CNS) infection...
Looking at Philosophy for Children and Its Outcomes Through a Neuroscience Lens [0.03%]
从神经科学的角度看哲学儿童教育及其成果
Fariba Khodagholi,Maryam Alsadat Mousavi,Yahya Ghaedi et al.
Fariba Khodagholi et al.
Introduction: Philosophy for Children (P4C) is one of the most effective teaching methods, having various educational, cognitive, and emotional benefits for children. This method is based on three types of thinking: criti...