Zolbetuximab Plus Chemotherapy as First-Line Treatment in Patients with Claudin 18.2-Positive, HER2-Negative, Locally Advanced Unresectable or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma: Korean Population Subgroup-Combined Efficacy and Safety Analysis from SPOTLIGHT and GLOW [0.03%]
Zolbetuximab联合化疗用于Claudin 18.2阳性、HER2阴性局部晚期不可切除或转移性胃癌或 gastroesophageal junction腺癌一线治疗的疗效和安全性分析:SPOTLIGHT和GLOW研究韩国亚组人群结果
Keun-Wook Lee,Sang Cheul Oh,Jong Gwang Kim et al.
Keun-Wook Lee et al.
Purpose: The phase 3 SPOTLIGHT and GLOW trials, in patients with claudin 18 isoform 2-positive, human epidermal growth factor receptor 2-negative, locally advanced unresectable or metastatic gastric or gastroesophageal ju...
Silence of Transmembrane Channel-Like 5 Inhibits Cell Proliferation, Migration, and Invasion While Promoting Apoptosis Via Deactivating the AKT Pathway in Breast Cancer [0.03%]
跨膜通道样蛋白5的沉默通过抑制AKT通路抑制乳腺癌细胞增殖、迁移和侵袭并促进凋亡
Jinnan Wan,Yang Li,Zhimin Liu
Jinnan Wan
Purpose: Transmembrane channel-like 5 (TMC5) plays a tumor-promoting role in the progression of various tumors. However, its effect on regulating breast cancer cell function remains scarce. The current study aimed to eval...
Kidney Failure-Related Mortality in Patients with Cancer: Insights from the Cancer Public Library Database in South Korea [0.03%]
韩国癌症公共图书馆数据库在癌症患者中与肾功能衰竭相关的死亡率研究的新见解
Chang Seong Kim,Sang Heon Suh,Hong Sang Choi et al.
Chang Seong Kim et al.
Purpose: Kidney failure is associated with an increased risk of death. However, since the impact of kidney failure on overall and cancer-related mortality among individuals with cancer remains unclear, we investigated kid...
Association between FGFR2b Positivity and Survival Outcomes of Patients with Gastric Cancer Treated with First-Line Nivolumab Plus Chemotherapy [0.03%]
FGFR2b阳性与一线纳武利尤单抗联合化疗胃癌患者生存结局的关联性分析
Hyung-Don Kim,Heonwoo Lee,Hyungeun Lee et al.
Hyung-Don Kim et al.
Purpose: Fibroblast growth factor receptor 2b (FGFR2b) is a promising therapeutic target in gastric cancer; however, its clinical relevance in immune checkpoint inhibitor (ICI)-based chemotherapy remains unclear. Therefor...
Skeletal Muscle Index to Red Cell Distribution Width Ratio: A Novel Prognostic Indicator for Patients with Stage I-III Colorectal Cancer [0.03%]
新型预后指标骨骼肌指数与红细胞分布宽度比值:Ⅰ~Ⅲ期结直肠癌患者的一项研究
Jiahn Choi,Jeonghyun Kang
Jiahn Choi
Purpose: Herein, a novel prognostic marker based on the skeletal muscle index (SMI) and red cell distribution width (RDW) for patients with colorectal cancer (CRC) was developed. ...
Dual-Functional PTX@Fe₃O₄ Nanobubbles: A Novel Theranostic Platform for Enhanced Ultrasound Imaging and Controlled Drug Delivery in Breast Cancer [0.03%]
兼具功能的PTX@Fe₃O₄纳米气泡:一种用于增强乳腺癌超声成像和控制给药的新诊疗平台
Weiyang Lv,Xiaomei Ning,Chunxin Huang et al.
Weiyang Lv et al.
Purpose: This study aimed to develop a novel theranostic nanoplatform that integrates ultrasound imaging and controlled drug delivery for the treatment of breast cancer. ...
The Application of Contrast-Enhanced Ultrasound Combined with Indocyanine Green Lymphography in the Management of Secondary Upper Limb Lymphedema [0.03%]
对比增强超声联合吲哚青绿淋巴造影在二期上肢淋巴水肿治疗中的应用研究
Xilong Gong,Lina Wang,Fang Liu et al.
Xilong Gong et al.
Purpose: To assess the clinical efficacy of contrast-enhanced ultrasound (CEUS) combined with indocyanine green (ICG) lymphography for the treatment of breast cancer-related lymphedema (BCRL). ...
Prognostic Factors for Relapse and the Role of Maintenance Therapy in Acute Promyelocytic Leukemia: A Real-World Multicenter Study in Korea [0.03%]
急性早幼粒细胞白血病的复发预测因素及巩固治疗的作用:一项韩国多中心真实世界研究
Kunye Kwak,Mihee Kim,Dongjin Shin et al.
Kunye Kwak et al.
Purpose: Acute promyelocytic leukemia (APL) is curable, but relapse remains a concern, particularly in patients treated with all-trans retinoic acid (ATRA) and chemotherapy-based regimens. The identification of prognostic...
Changes in Uptake, Participant Disparities, and Screening Outcomes of the Korean National Lung Cancer Screening Program: A Five-Year Experience [0.03%]
韩国全国肺癌筛查项目的五年经验:参与情况、参与者差异及筛查结果的变化趋势分析
Chang Kyun Choi,Na-Young Lee,Mina Suh et al.
Chang Kyun Choi et al.
Purpose: Low-dose computed tomography (LDCT) is effective in reducing lung cancer mortality among high-risk smokers. The Korean National Lung Cancer Screening Program (KNLCS), the world's first nationwide lung cancer scre...
Chemotherapy-Free Salvage Therapy with Rituximab, Lenalidomide, and Poseltinib in Relapsed or Refractory Primary Central Nervous System Lymphoma: A Multi-Center, Phase II Study [0.03%]
利妥昔单抗、来那度胺和泊马替尼联合治疗复发/难治性原发中枢神经系统淋巴瘤的无化疗挽救方案:一项多中心II期临床研究
Dong Hyun Kim,Sanyeowool An,Hongyul Ahn et al.
Dong Hyun Kim et al.
Purpose: Relapsed or refractory (R/R) primary central nervous system lymphoma (PCNSL) is an aggressive malignancy for which salvage chemotherapy has limited efficacy. We conducted an investigator-initiated, single-arm, mu...