Safety and Efficacy of Combining Metastasis-Directed Stereotactic Ablative Radiation Therapy with Tyrosine Kinase Inhibitors Versus Immune Checkpoint Inhibitors in Metastatic Hepatocellular Carcinoma [0.03%]
联合酪氨酸激酶抑制剂与免疫检查点抑制剂进行转移灶导向立体定向消融放射治疗以治疗转移性肝细胞癌的安全性和有效性：一项前瞻性随机2期试验
Eunyeong Yang,Jeong Il Yu,Hee Chul Park et al.
Eunyeong Yang et al.
Purpose: Immune checkpoint inhibitors (ICIs) have become a standard therapy for metastatic hepatocellular carcinoma (HCC), often as an alternative to tyrosine kinase inhibitors (TKIs). However, safety data combining ICIs ...
Associations between Smoking, Opioid Analgesic Use, and Risk For Chemical Coping in Korean Patients with Advanced Cancer [0.03%]
韩国晚期癌症患者中吸烟、阿片类药物使用与化学应对风险之间的关联
Eun Hee Jung,Yu Jung Kim,Rony Dev et al.
Eun Hee Jung et al.
Purpose: We investigated the associations between smoking, pain expression, opioid use, substance use behaviors, coping strategies, and risk of chemical coping in Korean patients with advanced cancer. ...
A Novel Classification of Esophageal Anastomotic Leaks and Its Impact on Healing Time After Esophagogastrostomy [0.03%]
食管吻合术后食管吻合口漏的新分类及其对愈合时间的影响
Zhao Ma,Jie Zheng,Hongbo Wang et al.
Zhao Ma et al.
Purpose: Anastomotic leakage (AL) is a severe complication after esophagogastrostomy, yet the classifications of AL and their associated healing times are poorly understood. ...
Understanding the Unmet Needs in Diagnostics and Therapeutics of Chronic Lymphocytic Leukemia in Korea [0.03%]
理解韩国慢性淋巴细胞白血病在诊断和治疗方面的未满足需求
Eun Sang Yu,Soyean Kwon,Seonggyu Byeon et al.
Eun Sang Yu et al.
Purpose: Since the FDA approval of ibrutinib in 2012, the treatment landscape for chronic lymphocytic leukemia (CLL) and small lymphocytic lymphoma (SLL) has undergone a paradigm shift. Nevertheless, the disease remains i...
A Phase I/II Trial to Evaluate the Safety and Efficacy of Continuous Positive Airway Pressure in Volumetric Modulated Arc Therapy for Breast Cancer [0.03%]
连续阳性气道压力在乳腺癌体调弧形治疗中的安全性和有效性的I/II期试验
Jung Bin Park,Tosol Yu,Jaeman Son et al.
Jung Bin Park et al.
Purpose: This phase I/II study aimed to evaluate the tolerability and the organ-sparing effects of continuous positive airway pressure (CPAP) in breast cancer radiotherapy (RT). ...
Circulating Tumor Cell-based Molecular Responses Stratify EGFR-TKI Efficacy in Patients with EGFR-Mutant Lung Cancer [0.03%]
基于循环肿瘤细胞的分子反应可对EGFR突变型肺癌患者TKI疗效进行分层
Seoyoung Lee,Chaeyeon Kim,Chang Gon Kim et al.
Seoyoung Lee et al.
Purpose: Circulating tumor cell (CTC) is a promising minimally invasive biomarker for EGFR-mutant non-small cell lung cancer (NSCLC). However, the rarity of CTCs and limitations in their isolation and molecular characteri...
Biomarker Testing Practices for Non-small Cell Lung Cancer: Survey Insights from South Korean Pathology Laboratories [0.03%]
韩国病理实验室非小细胞肺癌生物标志物检测实践调查见解
Sehui Kim,Dajeong Kim,Lucia Kim et al.
Sehui Kim et al.
Purpose: Molecular biomarker testing is essential for lung cancer management and precision medicine. This study evaluated biomarker testing practices for non-small cell lung cancer across pathology laboratories in South K...
Radiomics-Based Prediction of Lymphedema after Radiotherapy in Breast Cancer: Integrating Clinical and Dosimetric Features [0.03%]
基于影像组学的乳腺癌放疗后淋巴水肿预测：临床和剂量学特征的整合分析
Jae Sik Kim,Seung Hyuck Jeon,Bum-Sup Jang et al.
Jae Sik Kim et al.
Purpose: Arm lymphedema is a common, debilitating complication in patients with breast cancer undergoing postoperative radiotherapy (PORT). Although clinical and dosimetric factors have been used for risk prediction, radi...
Pre-Treatment Ki67 Index for Everolimus Efficacy in Patients with Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Multicenter Cohort Study [0.03%]
一项关于来那替尼疗效的预处理Ki67指数：绝经后激素受体阳性且HER2阴性晚期乳腺癌患者的多中心队列研究
Yujing Tan,Hanfang Jiang,Fei Ma et al.
Yujing Tan et al.
Purpose: The study aims to explore the predictive value of the Ki67 index for everolimus efficacy in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breas...
Salidroside-Loaded, TMTP1-Modified CSC-Exosomes Reprogram the PI3K/AKT/mTOR Axis to Overcome PD-1 Resistance in Breast Cancer [0.03%]
TMTP1修饰的飞鼠胶质母细胞瘤细胞来源的外泌体递送山柳苷胺重编程PI3K/Akt/mTOR轴以克服乳腺癌PD-1耐药性
Faxiang Yin,Xin Jin,Ligong Zhang et al.
Faxiang Yin et al.
Purpose: To elucidate how Salidroside-loaded, oligopeptide-modified tumor exosomes (Salidroside@T-exo) rewire the PI3K/AKT/mTOR axis to remodel the immune microenvironment (IME) and reverse acquired PD-1 resistance in bre...