Multimodal Knowledge Graph-Guided RAG-LLM for Clinical Decision Support in Pediatric Leukemia [0.03%]
多模态知识图谱引导的RAG-LLM在儿童白血病临床决策支持中的应用
Jong Keon Song,Dong Bin Youk,Hyery Kim et al.
Jong Keon Song et al.
Purpose: This study aims to develop and evaluate a multimodal, knowledge graph-guided retrieval-augmented generation (RAG) framework for clinical decision support in pediatric acute leukemia. ...
Toward Sustainable Care in HER2-Positive Metastatic Breast Cancer: Emerging Evidence for Treatment De-escalation [0.03%]
HER2阳性转移性乳腺癌治疗降级的新兴证据助力可持续医疗护理
Matilda Xinwei Lee,Soo Chin Lee
Matilda Xinwei Lee
Major advances in the management of HER2-positive (HER2+) metastatic breast cancer (MBC) have been achieved through treatment intensification with novel HER2-targeted agents and combination strategies, resulting in substantial survival gain...
Is Complete Mesocolic Excision with Central Vascular Ligation Necessary for Suspected Early-stage Right-sided Colon Cancer? [0.03%]
中央血管结扎的完全mesocolon切除术适用于疑似早期升结肠癌吗？
Mi Jeong Choi,Duck-Woo Kim,Yu Kyung Jun et al.
Mi Jeong Choi et al.
Purpose: To assess lymph node status in patients undergoing additional surgery after endoscopic resection to evaluate the need for complete mesocolic excision with central vascular ligation for clinically suspected early-...
Therapeutic Potential of Engineered Stem Cell Line with Chemokine Receptors and TRAIL/CD::UPRT in Glioblastoma Treatment [0.03%]
基因工程干细胞在胶质母细胞瘤治疗中的潜在作用：趋化因子受体和TRAIL/CD::UPRT的作用
Stephen Ahn,Soon Min Lee,Hyo-Jin Kim et al.
Stephen Ahn et al.
Purpose: Glioblastoma (GBM) is an aggressive primary brain tumor marked by a poor prognosis and limited effectiveness of current therapies, which are often accompanied by substantial recurrence rates. To address this chal...
Comparative Effectiveness of Tafasitamab Plus Lenalidomide versus Ifosfamide, Carboplatin, Etoposide-Based Chemotherapy for Relapsed/Refractory Diffuse Large B-cell Lymphoma: An External Control Arm Study [0.03%]
塔法西单抗联合来那度胺治疗复发或难治性弥漫大B细胞淋巴瘤的效果不低于异环磷酰胺、卡铂和依托泊苷等化疗药物：一种外部对照臂研究
Kyungyeon Jung,Ju Hwan Kim,Hyunjoo Lim et al.
Kyungyeon Jung et al.
Purpose: L-MIND trial has demonstrated efficacy of tafasitamab plus lenalidomide in patients with relapsed/refractory diffuse large B-cell lymphoma (r/r DLBCL). However, real-world evidence comparing tafasitamab plus lena...
Synergistic Antitumor Activity of Combination Therapy with a MET TKI Vabametkib and a Third-Generation EGFR TKI Lazertinib in MET-Amplified EGFR-Mutant NSCLC [0.03%]
MET扩增的EGFR突变型非小细胞肺癌中MET酪氨酸激酶抑制剂Vabencilimab与第三代表皮生长因子受体酪氨酸激酶抑制剂Lazertinib联合治疗的协同抗肿瘤活性研究
Dong Kwon Kim,Jin Woo Park,Hyeon Bin Cho et al.
Dong Kwon Kim et al.
Purpose: Third-generation epidermal growth factor receptor tyrosine kinase inhibitor (EGFR TKIs) improved outcomes in EGFR-mutant non-small cell lung cancer (NSCLC); however, the subsequent development of resistance empha...
Kyu-Won Jung,Mee Joo Kang,Eun Hye Park et al.
Kyu-Won Jung et al.
Purpose: This study aimed to project cancer incidence and mortality for 2026 to estimate Korea's current cancer burden. Materials and methods: ...
Cancer Statistics in Korea: Incidence, Mortality, Survival, and Prevalence in 2023 [0.03%]
2023年韩国癌症统计：发病率、死亡率、生存率和现患率
Eun Hye Park,Kyu-Won Jung,Seo Hyun Choi et al.
Eun Hye Park et al.
Purpose: The current study provides national cancer statistics and their secular trends in Korea, including incidence, mortality, survival, and prevalence in 2023, with international comparisons. ...
Korean Colorectal Cancer Screening Guidelines for Asymptomatic, average-Risk Adults: The 2025 Revision [0.03%]
2025年韩国无症状、平均风险成人结直肠癌筛查指南修订版
EunKyo Kang,Jae Myung Cha,Seo Young Kang et al.
EunKyo Kang et al.
Purpose: To develop the 2025 update to the Korean colorectal cancer (CRC) screening guidelines by systematically assessing recent evidence, integrating domestic data, and addressing changes since the 2015 guideline revisi...
Spatial Interactions of CD103+ Tissue-Resident Memory T Cells in the Tumor Periphery Are Associated with Clinical Outcomes in Triple-Negative Breast Cancer Following Neoadjuvant Chemotherapy [0.03%]
三阴性乳腺癌新辅助化疗后肿瘤周围CD103⁺组织驻留记忆T细胞的空间相互作用与临床结果相关
Hyun Lee,Byung-Kwan Jeong,Gyungyub Gong et al.
Hyun Lee et al.
Purpose: Triple-negative breast cancer (TNBC) is an aggressive subtype with poor prognosis. CD103+ tissue-resident memory T (TRM) cells are crucial for anti-tumor immunity in TNBC. We investigated whether their spatial in...