Circulating Tumor Cell-based Molecular Responses Stratify EGFR-TKI Efficacy in Patients with EGFR-Mutant Lung Cancer [0.03%]
基于循环肿瘤细胞的分子反应可对EGFR突变型肺癌患者TKI疗效进行分层
Seoyoung Lee,Chaeyeon Kim,Chang Gon Kim et al.
Seoyoung Lee et al.
Purpose: Circulating tumor cell (CTC) is a promising minimally invasive biomarker for EGFR-mutant non-small cell lung cancer (NSCLC). However, the rarity of CTCs and limitations in their isolation and molecular characteri...
Biomarker Testing Practices for Non-small Cell Lung Cancer: Survey Insights from South Korean Pathology Laboratories [0.03%]
韩国病理实验室非小细胞肺癌生物标志物检测实践调查见解
Sehui Kim,Dajeong Kim,Lucia Kim et al.
Sehui Kim et al.
Purpose: Molecular biomarker testing is essential for lung cancer management and precision medicine. This study evaluated biomarker testing practices for non-small cell lung cancer across pathology laboratories in South K...
Radiomics-Based Prediction of Lymphedema after Radiotherapy in Breast Cancer: Integrating Clinical and Dosimetric Features [0.03%]
基于影像组学的乳腺癌放疗后淋巴水肿预测：临床和剂量学特征的整合分析
Jae Sik Kim,Seung Hyuck Jeon,Bum-Sup Jang et al.
Jae Sik Kim et al.
Purpose: Arm lymphedema is a common, debilitating complication in patients with breast cancer undergoing postoperative radiotherapy (PORT). Although clinical and dosimetric factors have been used for risk prediction, radi...
Pre-Treatment Ki67 Index for Everolimus Efficacy in Patients with Hormone Receptor-Positive and Human Epidermal Growth Factor Receptor 2-Negative Advanced Breast Cancer: A Multicenter Cohort Study [0.03%]
一项关于来那替尼疗效的预处理Ki67指数：绝经后激素受体阳性且HER2阴性晚期乳腺癌患者的多中心队列研究
Yujing Tan,Hanfang Jiang,Fei Ma et al.
Yujing Tan et al.
Purpose: The study aims to explore the predictive value of the Ki67 index for everolimus efficacy in patients with hormone receptor-positive and human epidermal growth factor receptor 2-negative (HR+/HER2-) advanced breas...
Salidroside-Loaded, TMTP1-Modified CSC-Exosomes Reprogram the PI3K/AKT/mTOR Axis to Overcome PD-1 Resistance in Breast Cancer [0.03%]
TMTP1修饰的飞鼠胶质母细胞瘤细胞来源的外泌体递送山柳苷胺重编程PI3K/Akt/mTOR轴以克服乳腺癌PD-1耐药性
Faxiang Yin,Xin Jin,Ligong Zhang et al.
Faxiang Yin et al.
Purpose: To elucidate how Salidroside-loaded, oligopeptide-modified tumor exosomes (Salidroside@T-exo) rewire the PI3K/AKT/mTOR axis to remodel the immune microenvironment (IME) and reverse acquired PD-1 resistance in bre...
Trends in Incidence and Survival of Childhood and Adolescent Cancer in Korea, 2001-2020: Comparison with U.S. SEER Data [0.03%]
2001至2020年韩国儿童及青少年癌症的发病率和生存率变化趋势及其与美国SEER数据的对比
Jin Kyung Suh,Eun Hye Park,Meerim Park et al.
Jin Kyung Suh et al.
Purpose: Childhood cancers are rare but clinically significant. Monitoring incidence and survival trends is essential for evaluating progress in cancer control and identifying areas for improvement. ...
Smoking, Alcohol, and Abdominal Obesity Increase Gastric Cancer Risk after Helicobacter pylori Eradication [0.03%]
根除幽门螺杆菌后，吸烟、饮酒和腹型肥胖增加胃癌风险
Joo Hyun Lim,Cheol Min Shin,Kyungdo Han et al.
Joo Hyun Lim et al.
Purpose: Helicobacter pylori is the single most important risk factor for gastric cancer (GC). However, H. pylori eradication (HPE) does not eliminate risk of GC. To clarify the association of lifestyle factors with GC ri...
Unplanned Readmission among Patients with Advanced Cancer on Active Treatment: Multi-Center, Retrospective Study [0.03%]
晚期肿瘤接受治疗患者的非计划再入院：多中心回顾性研究
Sun Young Lee,Hong Jun Kim,Shin Hye Yoo et al.
Sun Young Lee et al.
Purpose: Unplanned readmissions of patients with cancer increase healthcare costs and disrupt care. Although well-studied in surgical oncology, data on patients receiving active treatment for advanced cancer remain limite...
A Prospective Study of Non‑Treating Medical Institution Use for Supportive Care During Adjuvant Chemotherapy After Curative Surgery (PRO-SUCCESS) [0.03%]
治愈性手术后辅助化疗期间非治疗医疗机构支持护理的前瞻性研究（PRO-SUCCESS）
So Yeon Oh,Kwonoh Park,Sang-Bo Oh et al.
So Yeon Oh et al.
Purpose: Patients undergoing adjuvant chemotherapy often utilize non‑treating medical institutions (NTMIs) for supportive care. We investigated utilization patterns and associated clinical factors. ...
Diagnostic Challenges and Clinical Implications of Microsatellite Instability/Mismatch Repair Deficiency in Solid Tumors [0.03%]
微卫星不稳定性/错配修复缺陷在实体瘤中的诊断挑战及临床意义
Yoonjin Kwak,Jeong Mo Bae,Hye Seung Lee
Yoonjin Kwak
The mismatch repair (MMR) system plays a crucial role in correcting replication errors; when the MMR system is deficient (dMMR), replication errors (particularly within microsatellites) accumulate throughout the genome, leading to microsate...