Tumor-Intrinsic Hepatocyte Arm-Level Genomic States Shape Immunotherapy Response Heterogeneity in Hepatocellular Carcinoma [0.03%]
肝细胞臂水平基因组状态塑造肝癌免疫治疗反应异质性
Kyuhyung Choi,Hojun Sung,Sunmin Kim et al.
Kyuhyung Choi et al.
Purpose: Bulk transcriptomic biomarkers for immune checkpoint inhibitor (ICI) response in hepatocellular carcinoma (HCC) often lack reproducibility because bulk RNA sequencing captures composite signals from malignant, im...
Clinical Effectiveness and Cost-Effectiveness of Robot-Assisted Versus Conventional Esophagectomy [0.03%]
机器人辅助食管切除术与传统食管切除术的临床疗效及成本效益分析
Joon Beom Park,Myung-Il Hahm,Hong Kwan Kim et al.
Joon Beom Park et al.
Purpose: This study evaluated the comparative clinical effectiveness and cost-effectiveness of robot-assisted minimally invasive esophagectomy (RAMIE) versus open esophagectomy (OE) and conventional minimally invasive eso...
A Multinational, Retrospective, Real-World Study: Treatment Patterns in Patients With HER2-Positive Locally Advanced or Metastatic Gastric or Gastroesophageal Junction Adenocarcinoma Beyond First-line in East Asia (HER2+ GASTA Study) [0.03%]
一项在东亚地区HER2阳性局部晚期或转移性胃癌或 gastroesophageal junction腺癌患者中一线之后治疗模式的跨国回顾性真实世界研究(HER2+GASTA研究)
Do-Youn Oh,Winnie Yeo,Jen-Shi Chen et al.
Do-Youn Oh et al.
Purpose: East Asia has the highest gastric cancer incidence globally [1]. Real-world (rw) treatment patterns and outcomes for HER2-positive (HER2+) advanced gastric or gastroesophageal junction cancer (aGC/GEJC) remain po...
Individual SGLT-2 Inhibitors and Risk of New-Onset Cancer in Type 2 Diabetes: A Nationwide Population-Based Cohort Study [0.03%]
口服钠葡萄糖共转运蛋白2抑制剂与2型糖尿病患者新发癌症风险：基于全国人群的队列研究
Hayeon Kim,Jun-Ho Seo,Jin Hyun Nam et al.
Hayeon Kim et al.
Purpose: Preclinical studies suggest that sodium-glucose cotransporter-2 inhibitors (SGLT-2is) may have cancer-preventive effects; however, clinical evidence remains inconclusive. Therefore, this study aimed to evaluate t...
Perceptions and Use of Complementary and Alternative Medicine among Patients with Cancer and Their Family Members (KCSG PC21-19) [0.03%]
癌症患者及其家属对补充和替代医学的感知和使用(KCSG PC21-19)
Young-Woong Won,Sun Young Rha,Jung Hye Kwon et al.
Young-Woong Won et al.
Purpose: This study aimed to assess the awareness, perception, and utilization of complementary and alternative medicine (CAM) among Korean patients with cancer and their caregivers. Furthermore, it evaluated CAM informat...
Spatial Disparities in Stage-Specific Breast Cancer Incidence and Area-Level Risk Factors in Korea, 2005-2018 [0.03%]
基于2005-2018年韩国妇女乳腺癌发病的阶段特异性和地方性危险因素的空间差异分析
Eun Hye Park,Kyu-Won Jung,Seung-Sik Hwang et al.
Eun Hye Park et al.
Purpose: Despite a nationwide breast cancer screening program in Korea, spatial disparities in stage at diagnosis persist. This study aimed to examine disparities in breast cancer incidence by stage and their association ...
Randomized Phase II Study of Bortezomib, Lenalidomide, and Dexamethasone (VRD) Versus Lenalidomide and Dexamethasone (RD) in Elderly Patients with Newly Diagnosed Multiple Myeloma (KMM1910) [0.03%]
硼替佐米、来那度胺和地塞米松(VRD)与来那度胺和地塞米松(RD)治疗老年新诊断多发性骨髓瘤患者的II期随机研究(KMM1910)
Jun Ho Yi,Sang Eun Yoon,Ji Hyun Lee et al.
Jun Ho Yi et al.
Purpose: While triplet regimens are considered optimal for treatment of multiple myeloma (MM), the benefit of adding bortezomib to lenalidomide and dexamethasone remains prospective-wise unclear in elderly patients due to...
The Role of Adjuvant Chemotherapy in High-Risk Stage II Colon Cancer with Microsatellite Instability-High or DNA Mismatch Repair Deficiencies: A Multicenter Pooled Analysis (KCSG-CO24-03) [0.03%]
高危Ⅱ期微卫星不稳定性高的结肠癌或错配修复缺陷的结肠癌辅助化疗的作用：一项多中心荟萃分析(KCSG-CO24-03)研究
Joon Young Hur,Hana Kim,Soon Il Lee et al.
Joon Young Hur et al.
Purpose: The benefit of adjuvant chemotherapy (CTx) for high-risk stage II microsatellite instability-high (MSI-H)/mismatch repair deficient (dMMR) colon cancer remains controversial with discordant international guidelin...