Literature-Guided 6-Gene Signature for the Stratification of High-Risk Acute Myeloid Leukemia [0.03%]
基于文献的高危急性髓系白血病分层的六基因标志物
Jong Keon Song,Dong Hyeok Lee,Hyery Kim et al.
Jong Keon Song et al.
Purpose: Acute myeloid leukemia (AML) shows significant heterogeneity in therapeutic responses. We aimed to develop a gene signature for the stratification of high-risk pediatric AML using publicly available AML datasets,...
Differential Efficacy of Alpelisib by PIK3CA Mutation Site in Head and Neck Squamous Cell Carcinoma: An Analysis from the KCSG HN 15-16 TRIUMPH Trial [0.03%]
头颈鳞状细胞癌中阿尔泊利单抗对PIK3CA不同突变位点的疗效差异：来自KCSG HN 15-16 TRIUMPH试验的事后分析
Kyoo Hyun Kim,Shinwon Hwang,Min Kyoung Kim et al.
Kyoo Hyun Kim et al.
Purpose: The TRIUMPH trial was a biomarker-driven umbrella trial for patients with recurrent or metastatic head and neck squamous cell carcinoma (R/M HNSCC). This analysis focuses on the PIK3CAɑ inhibitor alpelisib (arm ...
Novel Breast Cancer Risk Assessment Tools for Pre- and Post-Menopausal Asian Women: Development and Validation in a Nationwide Mammographic Screening Cohort [0.03%]
针对亚洲绝经前和绝经后女性的新型乳腺癌风险评估工具的研发与验证：一项全国性乳腺筛查队列研究
Wonyoung Jung,Yong-Moon Mark Park,Sang Hyun Park et al.
Wonyoung Jung et al.
Purpose: Widely used breast cancer risk-prediction tools are based on data from Western countries, but risk factors may differ for Asian women. Hence, we aimed to develop a risk assessment tool for breast cancer in Asian ...
Dose-response Association Between Alcohol Consumption and Kidney Cancer Risk Differs According to Glycemic Status: A Nationwide Cohort Study of 9.4 Million Individuals [0.03%]
饮酒量与肾脏癌风险的剂量反应关系根据糖代谢状态而不同：一项关于940万个体的全国队列研究
Joo-Hyun Park,Jung Yong Hong,Kyungdo Han et al.
Joo-Hyun Park et al.
Purpose: Previous studies suggested an association between alcohol consumption and reduced kidney cancer risk. Given a potential interaction between alcohol's insulin-sensitizing effect and hyperglycemia-related insulin r...
ALYREF-Mediated Regulation of TBL1XR1 and KMT2E Synergistically Upregulates APOC1, Contributing to Oxaliplatin Resistance in Esophageal Cancer [0.03%]
ALYREF通过协同调节TBL1XR1和KMT2E上调APOC1介导的奥沙利铂耐药在食管癌中的作用机制研究
Jie Hu,Qilong Liu,Bi Feng et al.
Jie Hu et al.
Purpose: Esophageal cancer (EC) is a rapidly progressing malignancy characterized by a low survival rate and limited treatment success, largely due to late-stage detection, frequent recurrence, and a high propensity for m...
Lipid Metabolism Related Gene ACSL3 as a Biomarker for Predicting Immunotherapy Outcomes in Lung Adenocarcinoma [0.03%]
脂肪代谢相关基因ACSL3作为预测肺腺癌免疫治疗结局的生物标志物
Taiping He,Jinhan Hu,Haoyue Guo et al.
Taiping He et al.
Purpose: Investigate the role of lipid metabolism in the tumor immune microenvironment (TIME) of lung adenocarcinoma (LUAD) and identify vital lipid metabolism-related genes (LMRGs) that contribute to immunotherapy outcom...
Prognostic Value of POST-Treatment Extent of Tumor (POSTTEXT) System in Patients with Hepatoblastoma [0.03%]
术后肿瘤范围(POSTTEXT)系统在肝母细胞瘤患者中的预后价值评估研究
Hana Jeong,Hee Mang Yoon,Pyeong Hwa Kim et al.
Hana Jeong et al.
Purpose: To assess prognostic values of the POST-Treatment Extent of Tumor (POSTTEXT) system and clinical factors after neoadjuvant chemotherapy in hepatoblastoma patients and evaluate benefits of posttreatment imaging an...
Clinical Characteristics of and Treatment Pattern for EGFR-Amplified Colorectal Cancer [0.03%]
表皮生长因子受体扩增型结直肠癌的临床特征和治疗模式
Seong-Eun Kim,Hyehyun Jeong,Sun Young Kim et al.
Seong-Eun Kim et al.
Purpose: To compare clinicopathologic features and clinical outcomes of metastatic colorectal cancer (mCRC) based on EGFR amplification status. Materials ...
Factors Associated with Smoking Cessation of Participants in the National Lung Cancer Screening Program in Korea [0.03%]
韩国全国肺癌筛查项目参与者戒烟的影响因素
Na-Young Yoon,Minji Seo,Nayoung Lee et al.
Na-Young Yoon et al.
Purpose: Smoking cessation interventions for participants in lung cancer screening are essential for increasing the effectiveness of screening to reduce lung cancer mortality. This study aimed to investigate the factors t...
The Roles of Ninjurin1 and Estrogen in Modulating AOM/DSS-Induced Colitis-Associated Colorectal Cancer in Male Mice [0.03%]
Ninjurin1和雌激素在调控雄性小鼠AOM/DSS诱导的结肠炎相关结直肠癌中的作用
Chin-Hee Song,Nayoung Kim,Ryoung Hee Nam et al.
Chin-Hee Song et al.
Purpose: Ninjury-induced protein 1 (Ninj1) is associated with inflammation and tumor progression and shows increased expression in various cancers. This study aimed to investigate the role of Ninj1 in colitis-associated c...