High prevalence of rhinitis symptoms without allergic sensitization in Estonia and Finland [0.03%]
爱沙尼亚和芬兰未产生过敏反应者的鼻炎高患病率
Paula Pallasaho,Annette Kainu,Maria Juusela et al.
Paula Pallasaho et al.
Objectives: Allergic rhinitis and atopy are more common in urban than rural environments. Non-allergic rhinitis has not been studied to a great extent. We aimed to assess the relationship of rhinitis symptoms with differe...
Pharmacology of novel treatments for COPD: are fixed dose combination LABA/LAMA synergistic? [0.03%]
新的COPD治疗药物的药理作用：LABA/LAMA固定剂量联合用药的协同效应证据充分吗？
Domenico Spina
Domenico Spina
Bronchodilators are mainstay for the symptomatic treatment of chronic obstructive pulmonary disease (COPD) and the introduction of long-acting bronchodilators has led to an improvement in the maintenance treatment of this disease. Various c...
Idiopathic fibrotic lung disease at a university hospital setting: management and prognostic factors [0.03%]
大学医院特发性肺纤维化患者的管理及预后因素分析
Parya Rad,Carl-Axel Karlsson,Christer Janson
Parya Rad
Background: Idiopathic fibrosing interstitial pneumonia consists of many subtypes, most associated with a poor prognosis. The aim of the study was to evaluate diagnostic procedures and treatment as well as survival in pat...
Pharmacological treatment of idiopathic pulmonary fibrosis - preclinical and clinical studies of pirfenidone, nintedanib, and N-acetylcysteine [0.03%]
特发性肺纤维化的药物治疗-吡非尼酮、尼达尼布和N-乙酰半胱氨酸的临床前及临床研究
Marjukka Myllärniemi,Riitta Kaarteenaho
Marjukka Myllärniemi
Three recent clinical trials on the pharmacologic treatment of idiopathic pulmonary fibrosis (IPF) mark a new chapter in the management of patients suffering from this very severe fibrotic lung disease. This review article summarizes the pu...
Improved asthma control in patients with severe, persistent allergic asthma after 12 months of nightly temperature-controlled laminar airflow: an observational study with retrospective comparisons [0.03%]
一项观察性研究及其与回顾性比较：在夜间采用温度控制的层流空气后，严重持续过敏性哮喘患者的病情得到改善
Uwe Schauer,Karl-Christian Bergmann,Michael Gerstlauer et al.
Uwe Schauer et al.
Introduction: Continuous or episodic allergen exposure is a major risk factor of frequent symptoms and exacerbations for patients with allergic asthma. It has been shown that temperature-controlled laminar airflow (TLA) s...
Diagnostic work-up in patients with possible asthma referred to a university hospital [0.03%]
疑似哮喘患者在大学医院的诊断检查流程
Vibeke Backer,Asger Sverrild,Charlotte Suppli Ulrik et al.
Vibeke Backer et al.
Objective: The best strategy for diagnosing asthma remains unclear. Accordingly, the aim of this study was to evaluate diagnostic strategies in individuals with possible asthma referred to a respiratory outpatient clinic ...
Reference values for spirometry - report from the Obstructive Lung Disease in Northern Sweden studies [0.03%]
来自瑞典北部阻塞性肺疾病研究的肺功能参考值报告
Helena Backman,Anne Lindberg,Anders Odén et al.
Helena Backman et al.
Background: Abnormal lung function is commonly identified by comparing observed spirometric values to corresponding reference values. It is recommended that such reference values for spirometry are evaluated and updated f...
Cigarette smoke-induced induction of antioxidant enzyme activities in airway leukocytes is absent in active smokers with COPD [0.03%]
慢性阻塞性肺病患者气道白细胞抗氧化酶活性的诱导反应缺失
Rosamund E Dove,Pheneatia Leong-Smith,Ester Roos-Engstrand et al.
Rosamund E Dove et al.
Background: Oxidative injury to the airway has been proposed as an important underlying mechanism in the pathogenesis of chronic obstructive pulmonary disease (COPD). As the extent of oxidant-mediated damage is dependent ...
Fabry disease, respiratory symptoms, and airway limitation - a systematic review [0.03%]
法布雷病、呼吸系统症状和气道受限：一项系统性综述
Camilla Kara Svensson,Ulla Feldt-Rasmussen,Vibeke Backer
Camilla Kara Svensson
Background: Fabry disease is an X-linked disorder caused by a deficiency of the lysosomal enzyme α-galactosidase A, resulting in accumulation of glycosphingolipids in multiple organs, primarily heart, kidneys, skin, CNS,...
Simon Francis Thomsen
Simon Francis Thomsen
This thesis explores the contribution of twin studies, particularly those studies originating from the Danish Twin Registry, to the understanding of the aetiology of asthma. First, it is explored how twin studies have established the contri...