Health-related quality of life in health states corresponding to different stages of perianal fistula associated with Crohn's disease: a quantitative evaluation of patients and non-patients in Japan [0.03%]
与克罗恩病不同阶段肛瘘相关的健康状态的生命质量评估：日本患者和非患者的量化评价研究
Masafumi Kato,Mariko Yoneyama-Hirozane,Katsuhiko Iwasaki et al.
Masafumi Kato et al.
Background: Perianal fistula (PF), a complication of Crohn's disease (CD), affects health-related quality of life (QOL). Objective: To ...
Cost-utility and value of information analysis of tisagenlecleucel for relapsed/refractory diffuse large B-cell lymphoma in the Irish healthcare setting [0.03%]
tisagenlecleucel用于治疗爱尔兰医疗环境中复发/难治性弥漫大B细胞淋巴瘤的成本效用和信息价值分析
Niamh Carey,Joy Leahy,Lea Trela-Larsen et al.
Niamh Carey et al.
Background: The evidence base of tisagenlecleucel is uncertain. Objective: To evaluate the cost-effectiveness of tisagenlecleucel. To c...
The association between body mass index groups and metabolic comorbidities with healthcare and medication costs: a nationwide biobank and registry study in Finland [0.03%]
不同身体质量指数亚组和代谢合并症与医疗保健及药物费用之间的关联：芬兰全国生物库及登记研究
Aino Vesikansa,Juha Mehtälä,Katja Mutanen et al.
Aino Vesikansa et al.
Background: The increasing prevalence of obesity imposes a significant cost burden on individuals and societies worldwide. Objective: I...
Cost-effectiveness of infant hypoallergenic formulas to manage cow's milk protein allergy in France [0.03%]
在法国使用婴儿水解蛋白配方奶粉管理牛奶蛋白过敏的成本效果分析
Ana Teresa Paquete,Rui Martins,Mark P Connolly et al.
Ana Teresa Paquete et al.
Background: Clinician's choice of hypoallergenic formulas in the first-line management of cow's milk protein allergy (CMPA) should be informed by evidence on clinical efficacy and cost-effectiveness. ...
Innovative technologies for reverse total shoulder arthroplasty in Australia: Market access challenges and implications for patients, decision-makers, and manufacturers [0.03%]
澳大利亚反向全肩关节置换术的创新技术：市场准入挑战及对患者、决策者和制造商的影响
Mutsa Gumbie,Michelle Costa,Michael Erb et al.
Mutsa Gumbie et al.
Purpose: The success of reverse total shoulder arthroplasty (RTSA) has expanded its use for a broader range of shoulder indications worldwide. Evidence regarding the relative efficacy and long-term safety of medical techn...
Machine-learning prediction for hospital length of stay using a French medico-administrative database [0.03%]
使用法国医疗管理数据库通过机器学习预测住院时间长度
Franck Jaotombo,Vanessa Pauly,Guillaume Fond et al.
Franck Jaotombo et al.
Introduction: Prolonged Hospital Length of Stay (PLOS) is an indicator of deteriorated efficiency in Quality of Care. One goal of public health management is to reduce PLOS by identifying its most relevant predictors. The...
Proposal of International Council for Harmonization (ICH) Guideline for the Approval of Biosimilars [0.03%]
国际协调会议（ICH）关于生物类似物批准的指导原则建议
Sarfaraz K Niazi,Waleed Mohammed Al-Shaqha,Zafar Mirza
Sarfaraz K Niazi
Objectives: Since the initial release of biosimilars 18 years ago, regulations for their licensing have changed considerably; however, there is no global consensus on these regulations. Establishing harmonized regulatory ...
Barriers in precision medicine implementation among Advanced Nonsquamous Cell Lung Cancer-patients: A Real-World Evidence Scenario [0.03%]
精准医学在晚期非鳞状细胞肺癌患者中的实施障碍：现实世界证据场景
Flavia A Duarte,Carlos Gil Ferreira,Rodrigo Dienstmann et al.
Flavia A Duarte et al.
Background: Precision oncology has a prominent role in nonsquamous non-small cell lung cancer (nsNSCLC) treatment progress; however, its access in a real-world scenario might be limited. ...
Impact of the COVID-19 pandemic on the conduct of clinical trials: a quantitative analysis [0.03%]
新冠疫情对临床试验实施影响的量化分析
Wojciech Margas,Piotr Wojciechowski,Mondher Toumi
Wojciech Margas
Background: Globally, healthcare has shouldered much of the socioeconomic brunt of the COVID-19 pandemic leading to numerous clinical trials suspended or discontinued. ...
Systematic literature review on the implicit factors influencing the HTA deliberative process in Europe [0.03%]
欧洲卫生技术评估审议过程中影响隐性因素的系统文献回顾
Clara Monleón,Hans-Martin Späth,Carlos Crespo et al.
Clara Monleón et al.
Objectives: Deliberative processes in Health Technologies Assessment (HTA) result in recommendations that determine the reimbursement of medicines, diagnostics or devices. These processes are governed by explicit criteria...