Functional characteristics of membrane vesicles produced by Streptococcus mitis [0.03%]
由肺炎链球菌产生的膜囊泡的功能特性
Airi Matsumoto,Yuichi Oogai,Haruka Kurashige et al.
Airi Matsumoto et al.
Objective: Mitis group streptococci (MGS) are the predominant oral bacteria that cause bacteremia and infective endocarditis. Although membrane vesicle (MV) secretion has been reported in Streptococcus pneumoniae among MG...
Microbiome differences between trauma- and caries-derived periapical lesions using next-generation sequencing [0.03%]
高通量测序技术分析外伤和龋病根尖周组织微生物群落差异性研究
Jiyuan Zhan,Yinxue Huang,Xinhui Meng et al.
Jiyuan Zhan et al.
Background: While the microbiome of caries-derived periapical lesions has been extensively characterized, the microbial profile of trauma-derived periapical lesions remains poorly understood. This study aimed to character...
Oral microbial signatures underlying recurrence via PI3K/AKT/mTOR pathway modulation in oral squamous cell carcinoma [0.03%]
PI3K/AKT/mTOR途径调节下口腔鳞状细胞癌复发的口腔微生物特征
Da-Woon Kwack,Zeba Praveen,Yeon-Hee Kim et al.
Da-Woon Kwack et al.
Background: Oral squamous cell carcinoma (OSCC) often recurs locally, reducing survival. The oral microbiome may influence tumor recurrence, but its prognostic role is unclear. This study investigated oral microbiomes ass...
Identification and functional validation of kynureninases from oral bacteria [0.03%]
口腔细菌犬尿氨酸酶的鉴定与功能验证
Pisit Charoenwongwatthana,Halah Ahmed,Alex Charlton et al.
Pisit Charoenwongwatthana et al.
Background: The kynurenine (KYN) pathway produces key metabolites for immunoregulation and neuromodulation in humans, but its presence and activity in the oral microbiome are unclear. This study investigates the functiona...
Hypochlorous acid solution serves as a potential anti-biofilm therapy for periodontitis via targeting quorum sensing of periodontal pathogens [0.03%]
次氯酸溶液通过靶向牙周病病原体的群体感应作用作为潜在的牙周炎抗生物膜疗法
Xuerong Lv,Xiang Han,Yiyang Yang et al.
Xuerong Lv et al.
Backgroud: Hypochlorous acid solution (HAS), a novel bio-friendly antimicrobial, has garnered attention for its antimicrobial activity, while less is known about its antibiofilm effects on periodontal pathogenic biofilms ...
Longitudinal analysis of oral microbiome changes during the neonatal period in full-term and preterm newborns [0.03%]
早产儿和足月新生儿生长期口腔微生物组的变化纵向分析
Taeyang Lee,Hyun-Yi Kim,Jung Ho Han et al.
Taeyang Lee et al.
Background: The neonatal period is critical for oral microbiome establishment, but temporal patterns in preterm newborns remain unclear. This study examined longitudinal microbiome changes in full-term and preterm newborn...
Postmenopausal osteoporosis increases periodontal inflammation and the pathogenicity of the oral microbiota in a rat model [0.03%]
绝经后骨质疏松通过大鼠模型增加牙周炎性并增加口腔微生物的致病性
Miao Lu,Yanan Zhang,Yang Zhang et al.
Miao Lu et al.
Objectives: This study aims to explore the mechanisms of the detrimental effects of postmenopausal osteoporosis (PMO) on periodontitis. Methods: ...
Functional and taxonomic dysbiosis of the supragingival plaque metagenome in Behçet's disease [0.03%]
贝赫切特病菌斑微生物组的功能和分类失衡
Thanyarat Sapthanakorn,Pitipol Choopong,Wasawat Sermsripong et al.
Thanyarat Sapthanakorn et al.
Background: Behçet's Disease (BD), a complex autoinflammatory disorder, is increasingly linked to microbial dysbiosis, yet the specific microbial signatures and their functional consequences remain incompletely character...
Cytokine release and NLRP3 inflammasome activation induced by low-abundance oral bacterial biofilms [0.03%]
低丰度口腔细菌菌斑诱导的细胞因子释放和NLRP3炎性小体活化
Maribasappa Karched,Radhika Guleri Bhardwaj,Manal Abu Al-Melh et al.
Maribasappa Karched et al.
Background: Low-abundance bacterial (LAB) species, despite their low prevalence, may contribute to oral inflammatory diseases by triggering host immune responses. The NLRP3 inflammasome plays a key role in inflammation, b...
Comparative pilot study of three commercial kits for bacterial DNA extraction from human subgingival biofilm samples collected with a single paper point [0.03%]
三种商业试剂盒从单张纸尖采集的人类附着龈生物膜样本中提取细菌DNA的比较研究
Janine Wäge-Recchioni,Renke Perduns,Kirstin Vach et al.
Janine Wäge-Recchioni et al.
Objective: In periodontal research, subgingival biofilm samples are typically collected using sterile paper points and pooled for molecular analyses. Streamlining this process by using a single paper point for molecular a...