Shotgun metagenomic analysis of the tongue-coating microbiome reveals oral microbes and their functions in older adults with dementia [0.03%]
基于高通量测序的舌苔微生物组变化与老年痴呆症的关系研究
Jun Hyung Cha,Sol-Ah Jeong,Byoung-Seok Ye et al.
Jun Hyung Cha et al.
Introduction: Dementia poses a growing burden in the aging population, prompting the search for noninvasive biomarkers for early detection. Materials and ...
P. gingivalis induces endothelial dysfunction via mitochondrial fission dependent VDAC1-HK2 disassociation [0.03%]
牙龈卟啉单胞菌通过线粒体分裂诱导电压依赖性阴离子通道1己糖激酶2分离来诱导内皮细胞功能障碍
Yi Wang,Shengming Xu,Zichao Zhuang et al.
Yi Wang et al.
Background: Mitochondrial dysfunction contributes to Porphyromonas gingivalis (P. gingivalis)-impaired endothelial function. Given the critical role of the mitochondrial permeability transition pore (mPTP) in mitochondria...
Supragingival Actinomyces naeslundii aggravates metabolic dysfunction-associated fatty liver disease via the oral-gut axis [0.03%]
牙龈上缘Actinomyces naeslundii菌通过口腔-肠道轴加重代谢紊乱相关性脂肪肝病
Ye Tu,Zhanyi Chen,Meiling Jing et al.
Ye Tu et al.
Background: Metabolic dysfunction-associated fatty liver disease (MAFLD) is the most prevalent chronic liver disease but lacks effective therapies. Oral microbial dysbiosis is closely associated with metabolic dysfunction...
Interrogation of imaging-based interspecies dynamics in the oral microbiome [0.03%]
基于影像的口腔微生物组互菌种动态研究
Zhenting Xiang,Zi Wang,Nikoo Ghasemi et al.
Zhenting Xiang et al.
Background: The oral cavity presents a highly dynamic environment where inter-microbial communications play a pivotal role. Understanding the spatial organization of microbial ecosystems has been highlighted on the microb...
Macrophage activation and invasion by P. gingivalis is modulated by PPAD and accessory fimbriae subunits [0.03%]
牙龈卟啉单胞菌通过PPAD和辅助菌毛亚基调节巨噬细胞活化和侵袭
Aleksandra Wielento,Dominika M Drapała,Marina Terekhova et al.
Aleksandra Wielento et al.
Background: Porphyromonas gingivalis is a master manipulator of host immune responses in the periodontium. Peptidyl arginine deiminase (PPAD), a recently identified virulence factor of P. gingivalis, responsible for citru...
The oral microbiome as a regulatory hub for systemic health: a systematic review of mechanistic links and clinical implications [0.03%]
口腔微生物组作为全身健康调控中心：机制联系及临床意义的系统性综述
Zhu Ling Guo,Ming Wang Cui,Yu Lei Dong et al.
Zhu Ling Guo et al.
Background: The human oral microbiome is a highly diverse ecosystem with important roles in oral and systemic health. Beyond dental caries and periodontitis, oral dysbiosis has been increasingly implicated in the developm...
Oral microbiota composition in children and adults during Spanish COVID-19 lockdown: impact of home self-confinement and SARS-CoV-2 infection [0.03%]
西班牙新冠肺炎封锁期间儿童及成人口腔微生物群组成变化：居家隔离和SARS-CoV-2感染的影响
Miguel Blanco-Fuertes,Gerard González-Comino,Pedro Brotons et al.
Miguel Blanco-Fuertes et al.
Background: The COVID-19 pandemic altered societal habits due to social restrictions and health measures implemented during the first half of 2020. Object...
Streptococcus dentisani 7746 encodes a cocktail of 14 bacteriocins associated with Com and Blp-like quorum sensing regulatory systems [0.03%]
链球菌7746编码一组与Com和Blp类似群体感应调节系统相关的14种细菌素
Ainhoa Revilla-Guarinos,Anny Camelo Castillo,Rubén Cebrián et al.
Ainhoa Revilla-Guarinos et al.
Aim: We explored in silico and in vitro the complete bacteriocin profile of the oral probiotic Streptococcus oralis subsp. dentisani strain 7746 with the primary objective of providing a descriptive analysis of bacterioci...
Association between diet quality and the oral microbiome in three US cohort studies [0.03%]
美国三项队列研究中饮食质量与口腔微生物组的关系
Fangyu Li,Samuel Anyaso-Samuel,Yukiko Yano et al.
Fangyu Li et al.
Background: The oral microbiome has been associated with overall health, but the contribution of dietary habits to oral microbial composition is not well understood. ...
Pulpitis as a microbial disease: single-cell insights into host responses and diagnostic biomarkers for vital pulp therapy [0.03%]
牙髓炎的微生物学：用于活髓治疗的宿主反应及诊断生物标志物的单细胞洞察
Tiansong Xu,Daishan Yang,Liqi Zhang et al.
Tiansong Xu et al.
Background: Pulpitis is a common dental disease driven by complex microbial infections, yet its microbial origins, diversity, and pathogenic mechanisms remain incompletely understood. A major clinical challenge is the abs...