Potential roles and mechanisms of bacterial peptidylarginine deiminase in dental biofilm mediated by Porphyromonas gingivalis [0.03%]
牙龈卟啉单胞菌介导的牙菌斑中细菌肽精氨达mine酶的潜在作用及其机制研究
Yitong Chen,Jiale Lou,Ying Fang et al.
Yitong Chen et al.
Background: Porphyromonas gingivalis, a keystone oral pathogen, secretes the enzyme peptidylarginine deiminase (PPAD), which catalyzes protein citrullination and is implicated in both dental biofilm formation and the path...
Polypharmacy, anticholinergic burden and oral microbiome among U.S. middle-aged and older adults: a representative national survey [0.03%]
美国中老年人的多重用药、抗胆碱能负担和口腔微生物组：一项全国代表性调查
Kai Wei,Yanping Yang,Chun Chen et al.
Kai Wei et al.
Objectives: Polypharmacy has been linked to alterations in gut microbiota, but its effects on the oral microbiome remain underexplored. This study aimed to examine the association of polypharmacy and anticholinergic burde...
Is systemic inflammation a missing link between oral microbiome and oral squamous cell carcinoma? Results from multi-omics integration analyses [0.03%]
口腔微生物组和口腔鳞状细胞癌之间的系统性炎症是缺失的环节吗？多组学整合分析的结果
Lingjun Yan,Baochang He,Qingrong Deng et al.
Lingjun Yan et al.
Objectives: To investigate whether systemic inflammation mediates the relationship between oral microbiome alterations and oral squamous cell carcinoma (OSCC) through multi-omics integration analyses. ...
Functional divergence of MdpS and MdpS2 reveals mucin-targeting strategies in Streptococcus oralis [0.03%]
MdpS和MdpS2的功能分歧揭示了Streptococcus oralis针对黏蛋白的目标策略
Fredrik Leo,Jonas Nilsson,Liisa Arike et al.
Fredrik Leo et al.
Background: Mucin degradation is essential for understanding oral microbial adaptation, yet the enzymes involved remain incompletely understood. Herein, we have characterised two mucin-degrading proteases, MdpS and MdpS2,...
Distinct trajectory of gut microbiota driven by a human oral commensal: insights from a murine study [0.03%]
来自小鼠研究的见解：由人体口腔共生菌驱动的肠道微生物群的独特轨迹
Wei-Ting Lin,Shiao-Pieng Lee,Chin Li et al.
Wei-Ting Lin et al.
Background: Oral microbes modulate the gut microbiota. Haemophilus parainfluenzae, a core human oral commensal with immunomodulatory properties, is reduced in autoimmune diseases, while mitigating Sjögren's syndrome-like...
The molecular mechanism of traditional Chinese medicine in the treatment of oropharyngeal candidiasis (OPC) [0.03%]
中药治疗口腔念珠菌病的分子机制研究进展
Shiqi Wang,Hongchen Wang,Wenfan Wei et al.
Shiqi Wang et al.
Background: Oropharyngeal candidiasis (OPC) is a prevalent fungal infection primarily caused by Candida species, notably Candida albicans, posing significant health challenges. Traditional Chinese medicine (TCM) has gaine...
Oral microbiome as a diagnostic biomarker for pancreatic cancer: a systematic review and meta-analysis of diagnostic accuracy [0.03%]
口腔微生物组作为诊断胰腺癌生物标志物的系统评价和诊断准确性Meta分析
Maryam Koopaie,Mahnaz Fatahzadeh,Sajad Kolahdooz
Maryam Koopaie
Background: This systematic review and meta-analysis aim to assess the diagnostic accuracy of the oral microbiome in detecting pancreatic cancer. Methods:...
Dysbiosis of the oropharyngeal microbiota in COVID-19: distinct profiles in patients with severe respiratory symptoms [0.03%]
新冠病毒感染患者的口腔咽部菌群失调及严重呼吸道症状患者的菌群特征分析
Sunitha Kumari V S,Varsha Potdar,Manohar Shinde et al.
Sunitha Kumari V S et al.
Background: COVID-19 has been strongly associated with alterations in the oropharyngeal microbiota, yet the microbial features linked to disease severity remain unclear. ...
Fangjie Zhou,Yajie Wu,Biao Ren et al.
Fangjie Zhou et al.
Background: The homeostasis of the subgingival microbiome is crucial for periodontal health, although the dynamics governing its community variation remain insufficiently studied. This study aims to investigate the dynami...
The role of oral microbiota in digestive system diseases: current advances and perspectives [0.03%]
口腔微生物在消化系统疾病中的作用：进展与展望
Yaqi Li,Yiping Xin,Wenlu Zong et al.
Yaqi Li et al.
The oral microbiota is intimately linked to human health and various disease states. With the advent of the Human Microbiome Project, our comprehension of the oral microbiota has substantially improved. This microbial community is not only ...