Salivary and tonsillar microbiota across multiple sites in paediatric tonsillar hypertrophy and their associations with clinical factors [0.03%]
儿童扁桃体肥大患者多个采样点的唾液及扁桃体菌群及其与临床因素的关系
Ying Xu,Min Yu,Yuhan Xu et al.
Ying Xu et al.
Background: Tonsillar hypertrophy (TH) and adenotonsillar hypertrophy (ATH) are primary risk factors for paediatric obstructive sleep apnoea (OSA), but their salivary microbiota differ. ...
Recognition of Porphyromonas gingivalis lipopolysaccharide by human caspase-4 depends on lipopolysaccharide purity and guanylate-binding protein 1 [0.03%]
牙龈卟啉单胞菌脂多糖被人的Caspase-4识别依赖于脂多糖的纯度和Guanimate结合蛋白1
Eisuke Domae,Taiki Mori,Mariko Hanaoka et al.
Eisuke Domae et al.
Background: Porphyromonas gingivalis, a key pathogen in chronic periodontitis, produces heterogeneous lipopolysaccharides (LPS) that are weakly recognized by Toll-like receptor 4 (TLR4). Human cells detect cytosolic LPS v...
Zijun Yue,Chunhao Li,Fangxu Yan et al.
Zijun Yue et al.
Background: Aging is characterized by progressive physiological decline and increased susceptibility to age-related diseases. The oral microbiome, a complex community of microorganisms, has been increasingly recognized as...
Spatial and temporal dynamic changes of oral microbiome in removable partial denture wearers: a longitudinal study using full-length 16S rRNA sequencing [0.03%]
可摘局部义齿佩戴者口腔微生物组的时空动态变化：一项基于全长16S rRNA测序的纵向研究
Xin Feng,Xueqi Gan,Biao Ren et al.
Xin Feng et al.
Objective: This longitudinal study aimed to characterize the spatial and temporal dynamics of oral microbiome colonization on removable partial dentures (RPDs) and corresponding dental surfaces at species-level resolution...
Characterisation of novel Fusobacterium nucleatum bacteriophages and their efficacy in disrupting pathogenic dual-species biofilms [0.03%]
新型核梭杆菌噬菌体的表征及其在破坏致病性双重物种生物膜方面的有效性
Mwila Kabwe,Joseph Tucci,Stuart Dashper et al.
Mwila Kabwe et al.
Background: The targeted manipulation of the microbiome using bacteriophages represents a novel approach for addressing antibiotic resistance and polymicrobial diseases. ...
Altered oral microbiomes in patients with prolonged disorders of consciousness [0.03%]
意识障碍患者口腔微生物群的变化
Mingwei Xu,Zhuolin He,Jiajia Zhou et al.
Mingwei Xu et al.
Background: The host microbiome is increasingly recognized as a key modulator of brain function and disease progression, yet the role of the oral microbiome in patients with prolonged disorders of consciousness remains un...
Effects of removable clear dental aligners on the composition of the oral microbiome [0.03%]
可摘隐形透明牙颌矫治器对口腔微生物组组成的影响
Sara Peregrina,Andrea Peiró Aubalat,Avié Manohar et al.
Sara Peregrina et al.
Proper tooth alignment is important for oral and periodontal health, allowing better hygiene and reducing plaque build-up. While traditional braces are effective, clear aligners offer an aesthetic advantage and are also thought to promote b...
Porphyromonas gingivalis sphingolipids impair neutrophil function and promote bacterial survival [0.03%]
牙龈卟啉单胞菌鞘脂损害中性粒细胞功能并促进细菌存活
Fatma Oner,Manda Yu,Carla Alvarez Rivas et al.
Fatma Oner et al.
Background: Porphyromonas gingivalis (P. gingivalis) is one of the few bacteria that can produce sphingolipids (SLs). Bacterial SLs have been shown to modulate the host immune response. ...
Inhibition of BTK and SYK attenuates Porphyromonas gingivalis -induced activation of the pyroptosis pathway and inflammation in host cells [0.03%]
BTK和SYK的抑制可减轻牙龈卟啉单胞菌诱导宿主细胞焦亡途径活化及炎症反应
Alicja Plonczynska,Aureliusz Schuster,Dominika M Drapala et al.
Alicja Plonczynska et al.
Background: Periodontitisis a chronic inflammatory disease of the oral cavity, primarily driven by periodontopathogens such as Porphyromonas gingivalis (Pg)." ...
Does a link exist between oral microbiota and oral squamous cell carcinoma? A review of current insights [0.03%]
口腔微生物与口腔鳞癌之间存在关联吗？当前研究见解综述
Luigi Santacroce,Emilio Jirillo,Lucrezia Bottalico et al.
Luigi Santacroce et al.
Background: Oral squamous cell carcinoma (OSCC) represents more than 90% of all oral cancers. Among the known risk factors, periodontal diseases are a significant contributor to OSCC development. The balance between the v...