Results of bacterial cultivation are infrequently utilized in the treatment of patients hospitalized with severe odontogenic infections - a retrospective cohort study [0.03%]
住院严重牙源性感染患者中细菌培养结果的使用率较低-一项回顾性队列研究
Rasmus Søndenbroe,Merete Markvart,Daniel Belstrøm et al.
Rasmus Søndenbroe et al.
Background: Patients hospitalized with severe odontogenic infections (SOI) receive empiric intravenous antibiotics. Microbiological cultivation and antibiotic susceptibility testing are commonly performed, although the cl...
Candida albicans is a context-dependent risk factor for malignant transformation of oral precancer lesions: a prospective cohort study of 734 Taiwanese patients [0.03%]
白色念珠菌是口腔癌前病变恶性转化的条件性危险因素：一项关于734名台湾患者的前瞻性队列研究
Shih Sheng Jiang,Chung-Hsing Chen,Fang-Yu Tsai et al.
Shih Sheng Jiang et al.
Background: Candida albicans has been implicated in oral carcinogenesis, but its role in the progression of oral potentially malignant disorders (OPMDs) remains unclear. We investigated whether high Candida burden in OPMD...
Tooth-surface plaque microbiome and different levels of oral disease burden among dentate older adults living in long-term care [0.03%]
长期护理机构中牙龄较大的老年人的牙面菌斑微生物组及其不同的口腔疾病负担水平
Lina Julkunen,Muhammed Manzoor,Kaija Hiltunen et al.
Lina Julkunen et al.
Aim: This study aimed to explore the composition of the tooth-surface plaque (subgingival with marginal supragingival) microbiome in dentate older adults residing in long-term care (LTC) facilities, stratified by clinical...
The Porphyromonas gingivalis lipid A 1-phosphatase LpxE requires a functional type IX secretion system for its activity [0.03%]
牙龈卟啉单胞菌脂多糖1-磷酸酶LpxE的活性需要功能性的IX型分泌系统
Sunjun Wang,Yichao Liu,Beichang Zhang et al.
Sunjun Wang et al.
Background: Porphyromonas gingivalis is a Gram-negative bacterium that plays a central role in the development of periodontal disease. It uses a type IX secretion system (T9SS) to export virulence factors to the bacterial surface where they...
Streptococcus suis exports WapA polymorphic toxins to compete with tonsil microbiota for an optimal colonization [0.03%]
肠球菌输出WapA毒力蛋白以适应隐窝微生物群竞争最佳定植位置
Xinming Pan,Jianan Liu,Ningyuan Zhong et al.
Xinming Pan et al.
Background: Streptococcus suis is a zoonotic pathogen, and its colonization of the host tonsil is believed to be a vital source causing infection, while its mechanism competing for a stable tonsil niche is unknown. Rearra...
Antibacterial and cytotoxic effects of chlorhexidine combined with sodium DNA on oral microorganisms: an in vitro study using Dictyostelium discoideum [0.03%]
氯己定联合钠DNA对口腔微生物的抗菌和细胞毒性作用的体外研究(采用变形虫模型)
Simone Rocco,Adriana Antonina Tempesta,Gaia Vertillo Aluisio et al.
Simone Rocco et al.
Background: Chlorhexidine (CHX) is widely used in oral care for its broad-spectrum antimicrobial activity but can cause significant side effects. Sodium DNA has emerged as a potential adjunct capable of modulating cellula...
Geographic signatures in the oral resistome: a comparative metagenomic analysis of healthy individuals from Thailand and Norway [0.03%]
口腔耐药基因组的地域特征：来自泰国和挪威健康个体的比较元基因组分析
Supathep Tansirichaiya,Kittikun Songsomboon,Johannes Wigand et al.
Supathep Tansirichaiya et al.
Background: The oral cavity is an important yet understudied reservoir of antimicrobial resistance genes (ARGs), potentially shaped by geographic variation in antibiotic usage. ...
Dental caries shallow-layer microbe harvest and data display method shows taxa pre-harvest spatial positions, absolute and relative abundance and diversity related to lesion pulpal depth [0.03%]
牙釉质浅层微生物采样和数据显示方法展示门类采样前的空间位置、绝对数量、相对丰度及与病灶根髓深度有关的多样性
Rella P Christensen,Brad J Ploeger,Kaesy R Barker et al.
Rella P Christensen et al.
Background: Molecular identification of dental caries microbes is advancing rapidly, yet sampling methods remain outdated and imprecise. Objective: ...
Functional profiling of the oral microbiome reveals microbial and oncogenic signatures in never-smoking female patients with oral squamous cell carcinoma [0.03%]
口腔微生物组的功能特征鉴定出从未吸烟的女性口腔鳞癌患者中的微生物和致癌标志物
Sung Min Kim,Zeba Praveen,Yeon-Hee Kim et al.
Sung Min Kim et al.
Background: The pathogenesis of oral squamous cell carcinoma (OSCC) in never-smoking females remains poorly understood, as these patients lack traditional risk factors. This subgroup accounts for an increasing proportion ...
The oral microbiome as mediators in the association between smoking and all-cause mortality [0.03%]
吸烟与全因死亡率关联中的口腔微生物群的介导作用
Yue Xu,Xin Leng,Qi Liu et al.
Yue Xu et al.
Background: Smoking increases mortality risk and alters the oral microbiome, but its mediating role in the smoking-survival relationship remains unclear. This study examined whether oral microbiome diversity mediates the ...