Comparison of 16S rRNA gene amplicon and whole-genome shotgun metagenomic sequencing for subgingival oral microbiome profiling [0.03%]
牙龈下口腔微生物组测序分析中16S rDNA扩增子与全基因组鸟枪法测序的比较研究
Jung Hwa Park,Jin Chung,Hyo-Jung Lee et al.
Jung Hwa Park et al.
Background: Periodontitis is a chronic inflammatory disease driven by a dysbiotic subgingival microbiome. While 16S rRNA gene amplicon sequencing is widely used, whole-genome shotgun (WGS) metagenomics is increasingly app...
Association between the oral microbiome and clinical indicators of resectable non-small cell lung cancer (NSCLC) [0.03%]
口腔微生物组与可手术非小细胞肺癌临床指标之间的关系
Vanessa DeClercq,Rowan E Murphy,Nick Zinck et al.
Vanessa DeClercq et al.
Background: Oral microbial implications for lung cancer outcomes and association with clinical markers are largely unknown. Objective: ...
The role of extracellular vesicles in intercellular communication within the oral cavity [0.03%]
口腔内细胞间通讯中胞外囊泡的作用
Abdelhabib Semlali,Mohammed Al-Zharani,Jassem Al-Ansari
Abdelhabib Semlali
Background: Extracellular vesicles (EVs), including exosomes, microvesicles, and apoptotic bodies, are nanoscale membrane-bound structures that mediate intercellular communication through the transfer of proteins, lipids,...
CRISPR spacer profiling and prophage mining reveal diverse bacteriophages associated with Streptococcus Mutans [0.03%]
CRISPR spacer测序和前噬菌体挖掘揭示了与变异链球菌相关的多样的噬菌体
Xiaolin Chen,Mingrui Zhang,Liuchang Yang et al.
Xiaolin Chen et al.
Background: Streptococcus mutans is a key cariogenic bacterium. Current antimicrobials lack species specificity, while phage-based approaches remain experimental and require more S. mutans phage isolates. ...
Evaluation of digital colorimetric analysis as an objective indicator representing microbial diversity and biological succession of dental plaque [0.03%]
数字色彩分析作为代表牙菌斑微生物多样性及生物演替客观指标的价值评估研究
Ji-Na Lim,Yunseok Oh,Kyudong Han et al.
Ji-Na Lim et al.
Background: Visual assessment of dental plaque is limited by subjectivity and variability in imaging conditions. Objective: This study ...
Bacteriome-based oral dysbiosis index in patients with oral squamous cell carcinoma [0.03%]
基于细菌组的口腔肿瘤患者的牙龈微生态失衡指数
David Szaraz,Jan Bohm,Ctirad Machacek et al.
David Szaraz et al.
Background: Oral dysbiosis plays an important role in the pathogenesis of oral squamous cell carcinoma (OSCC). Our study aimed to perform a pairwise comparison of the oral microbiota, especially the bacteriome, from OSCC ...
Co-infection with Cbp+ Streptococcus mutans and Candida albicans is associated with root caries in older adults [0.03%]
口腔中齿垢链球菌和白色念珠菌共感染与老年人根面龋有关
Bruna Albuquerque Garcia,Louise Morais Dornelas-Figueira,C Katrak et al.
Bruna Albuquerque Garcia et al.
Background: Gingival recession increases with age, exposing root surfaces and raising susceptibility to root caries. As the global population ages, root caries prevalence is expected to rise, underscoring the need to bett...
Microbial signatures of dental caries in the incarcerated elderly: a salivary microbiota study in a restricted environment [0.03%]
监禁老人患龋病的微生物标志物：限制性环境下唾液菌群的研究
Teeratas Kijpornyongpan,Annop Krasaesin,Thananya Chongcharoenkit et al.
Teeratas Kijpornyongpan et al.
Background: Dental caries is driven by microbial dysbiosis and influenced by diet and lifestyle. Incarcerated populations living under regulated regimens offer a unique model to study the oral microbiota in older adults b...
Treatment of periodontal biofilms via nitric oxide-augmented phototherapy [0.03%]
一氧化氮增强光治疗在牙周生物膜治疗中的应用
Courtney R Johnson,Tsian D Ramrattan,Casimir J Schaefer et al.
Courtney R Johnson et al.
Objectives: This study investigated the antibacterial action of photo-liberated nitric oxide (NO) from primary and tertiary S-nitrosothiol-modified mesoporous silica nanoparticles (1° RSNO-MSNs and 3° RSNO-MSNs, respect...
Metagenome-based virome analysis identifies the oral viral signatures for periodontitis [0.03%]
基于元基因组的病毒组分析鉴定出牙周炎口腔病毒标志物
Tianshu Chu,Jian Liu,Yue Zhang et al.
Tianshu Chu et al.
Background: Periodontitis (PD) is a chronic infectious disease driven by bacterial biofilms, yet the oral virome's role in pathogenesis remains poorly understood. ...