Antimicrobial susceptibility testing of Aggregatibacter Actinomycetemcomitans can be performed using the EUCAST medium for anaerobic bacteria [0.03%]
可使用欧盟厌氧菌鉴定板进行牙龈卟啉单胞菌的药物敏感性试验
Anne Birkeholm Jensen,Erika Matuschek,Gunnar Kahlmeter et al.
Anne Birkeholm Jensen et al.
Background: The oral bacterium Aggregatibacter actinomycetemcomitans (Aa) is associated with infectious diseases treated with antibiotics, but specific recommendations for antimicrobial susceptibility testing (AST) of the...
Oral microbiome-SASP-aging axis: mechanisms and targeted intervention strategies for age-related diseases [0.03%]
口腔微生物组-细胞内衰老相关分泌表型-衰老轴：与年龄相关的疾病的机制及靶向干预策略
Enfang Wu,Xueyu Li,Zichen Ni et al.
Enfang Wu et al.
Background: Global demographic aging is intensifying the burden of age-related diseases. Cellular senescence and the accompanying senescence-associated secretory phenotype (SASP) act as key drivers of disease progression ...
Oral Eikenella as a potential new biomarker of symptomatic carotid atherosclerosis [0.03%]
口腔伊克菌属作为症状性颈动脉粥样硬化的潜在新生物标志物
Kristine Stø,Karolina R Skagen,Kristian Holm et al.
Kristine Stø et al.
Introduction: Oral microbiota dysbiosis is linked to cardiovascular disease, and oral pathogens have been detected in atherosclerotic plaques. We aimed to investigate the relationship between the oral microbiota and carot...
Aggregatibacter actinomycetemcomitans exacerbates colitis and perturbs the gut microbiota in a murine model [0.03%]
牙龈密螺旋体加重结肠炎和破坏小鼠肠道菌群平衡
Xu Chen,Xiaoming Zhu,Yiran Liu et al.
Xu Chen et al.
Background: Chronic intestinal inflammation is a hallmark of inflammatory bowel disease (IBD). Studies suggest that salivary bacteria associated with periodontitis may exacerbate colitis, but the specific contributory mic...
Pyruvate metabolism is involved in adaptability and cariogenicity of Streptococcus mutans [0.03%]
丙酮酸代谢参与变异链球菌的适应性和致龋性
Shuxing Yu,Yaqi Liu,Dingwei Ye et al.
Shuxing Yu et al.
Dental caries is a biofilm-mediated disease that arises from polymicrobial dysbiosis in dental plaque. Among these microorganisms, Streptococcus mutans plays a prominent role because of its strong capacity to metabolize fermentable carbohyd...
Diagnostic oral microbiota signatures for gastric cancer and associations with carcinogenic signaling pathways [0.03%]
胃癌的诊断口腔微生物标志物及其与致癌信号通路的关系
Yeon-Hee Kim,Il Ju Choi,Keun Won Ryu et al.
Yeon-Hee Kim et al.
Background/objective: Gastric cancer (GC) is a major cause of cancer mortality worldwide. We evaluated whether oral microbiota could be sensitive, specific, and non-invasive markers for early GC detection. ...
Cross-sectional comparative shotgun metagenomic analysis of the subgingival resistome in healthy subjects and patients with periodontitis from four countries [0.03%]
四个国家的健康人和牙周炎患者菌斑基因组元基因组测序比较研究
A Arredondo,G Àlvarez,S Isabal et al.
A Arredondo et al.
Background: The oral cavity is a known reservoir of antibiotic resistance genes (ARGs), but little is known about their subgingival distribution across health states and regions. ...
Vendor-specific microbiomes influence oral cancer development and its response to Streptococcus mitis intervention in mice [0.03%]
口腔癌的发病及其对链球菌干预反应受供应商特定微生物群的影响
Doaa E El-Hadedy,Tsute Chen,Kathy Q Cai et al.
Doaa E El-Hadedy et al.
Background: We previously demonstrated that Streptococcus mitis exhibits anticancer properties in vitro. Here, we sought to validate these findings in vivo. Because mice from different vendors harbor distinct microbiomes ...
Oral microbiome diversity and all-cause mortality in hypertensive adults: findings from a nationally representative cohort [0.03%]
高血压成人口腔微生物多样性与全因死亡率：来自全国代表队列的发现
Zhe Zhou,Zichao Zhuang,Yipeng Ding et al.
Zhe Zhou et al.
Background: Oral microbiome diversity has been associated with general health. However, its association with long-term outcomes in hypertensive individuals remains unclear. ...