[Research Advances in Targeting the YAP/TAZ Signaling Pathway to Improve Cancer Immunotherapy] [0.03%]
靶向YAP/TAZ信号通路改善癌症免疫治疗的研究进展！
Pingxu Zhang,Yiyi Zhan
Pingxu Zhang
Despite the groundbreaking advances in cancer immunotherapy achieved by immune checkpoint inhibitors (ICIs), their efficacy remains limited by the immunosuppressive tumor microenvironment (TME). Yes-associated protein (YAP) and transcriptio...
[Immune Checkpoints Mediate Tumor Immune Regulation through Metabolic Pathways] [0.03%]
[免疫检查点通过代谢途径介导肿瘤免疫调控]
Weiguang Du,Xiyang Tang,Yulong Zhou et al.
Weiguang Du et al.
Immune checkpoints include a series of receptor-ligand pairs that play a key role in the proliferation, activation, and immune regulatory responses of immune cells. Although immune checkpoint inhibitors (ICIs), such as programmed death prot...
Xu Hao,Yilin Feng,Anqi Lu et al.
Xu Hao et al.
Neutrophil extracellular traps (NETs), intricate reticular structures released by activated neutrophils, play a pivotal regulatory role in the pathogenesis of malignant tumors. Lung cancer is one of the most prevalent malignancies globally,...
[Surgical Perspective on Lung Cancer in 2024: Innovation and Challenges] [0.03%]
[2024年肺癌外科视角：创新与挑战]
Pengxu Kong,Xiaohan Chen,Wang Lv et al.
Pengxu Kong et al.
Lung cancer, a highly prevalent and deadly malignancy globally, poses a significant disease burden in China and is the leading cause of cancer death. Despite rapid advances in medicine, its incidence and mortality rates remain stubbornly hi...
[Comprehensive Analysis of the Expression, Prognosis and Function of TRAF Family Proteins in NSCLC] [0.03%]
[泛TRAF家族蛋白在NSCLC中的表达、预后和功能的全面分析]
Yixuan Wang,Qiang Chen,Yaguang Fan et al.
Yixuan Wang et al.
Background: Currently, lung cancer is one of the malignant tumors with a high morbidity and mortality all over the world. However, the exact mechanisms underlying lung cancer progression remain unclear. The tumor necrosis...
[Application Practice of AI Empowering Post-discharge Specialized Disease Management in Postoperative Rehabilitation of the Lung Cancer Patients Undergoing Surgery] [0.03%]
人工智能赋能术后专科疾病管理在肺癌手术患者康复期的应用实践
Mei Li,Hongbing Zhang,Chunqiu Xia et al.
Mei Li et al.
Background: Lung cancer is the leading malignancy in China in terms of both incidence and mortality. With increased health awareness and the widespread use of low-dose computed tomography (CT), early diagnosis rates have ...
[ARID1B Gene Deletion Promotes the Proliferation, Migration and Invasion of NSCLC Cells] [0.03%]
ARID1B基因缺失促进非小细胞肺癌的增殖、迁移和侵袭能力
Linlin Zhu,Xuchao Zhang
Linlin Zhu
Background: Abnormalities of the switch/sucrose nonfermentable (SWI/SNF) chromatin-remodeling complex are closely related to various cancers, and ARID1B (AT-rich interaction domain 1B) is one of the core subunits of the S...
[Epithelial-mesenchymal Transition: Biological Basis and Clinical Prospects of Lung Cancer Invasion, Metastasis, and Drug Resistance] [0.03%]
上皮间充质转化：肺癌侵袭、转移和耐药的生物学基础与临床展望
Hengxing Sun,Mengting Xiong,Shuanshuan Xie et al.
Hengxing Sun et al.
Lung cancer is the leading cause of cancer-related deaths worldwide, characterized by high incidence and mortality rates. The primary reasons for treatment failure in lung cancer patients are tumor invasion and drug resistance, particularly...
[Research Progress on Molecular Subtypes and Precision Therapy of Pulmonary Large Cell Neuroendocrine Carcinoma] [0.03%]
肺大细胞神经内分泌癌分子分型及精准治疗的研究进展
Yuchao Feng,Xiaohong Cao
Yuchao Feng
Pulmonary large cell neuroendocrine carcinoma (LCNEC) is a high-grade neuroendocrine tumor with unique characteristics, and its treatment regimens are primarily derived from those for small cell lung cancer (SCLC) and non-small cell lung ca...
[Crosstalk between Tumor Cells and Neural Signals in Neuroendocrine Carcinoma Metastasis: Communication Hijacking Based Perspective] [0.03%]
神经内分泌癌转移中肿瘤细胞与神经信号的串话：基于通讯劫持的观点
Shuping Song,Xinyi Wang,Siqi Zhou et al.
Shuping Song et al.
Neuroendocrine carcinoma (NEC) represents a category of malignant tumors originating from neuroendocrine cells. Given that NEC cells exhibit characteristics of both neural and endocrine cells, they can hijack neuronal signaling pathways and...