Natural Clinoptilolite as a Functional Mineral Component in Alginate Hybrid Microcapsules for Controlled Amoxicillin Release [0.03%]
用海藻酸盐混合微胶囊作为控制阿莫西林释放的功能性clinoptilolite成分
İrem Toprakçı,Ebru Kurtulbaş,Dorina Simedru et al.
İrem Toprakçı et al.
Background/Objectives: Natural clinoptilolite-amoxicillin hybrids (CNZ@AMOX) were incorporated into alginate microcapsules via ionic gelation to develop a hybrid mineral-polymer delivery system for the controlled release of amoxicillin. Met...
Silver-Doped Mesoporous Calcium Phosphate for Controlled Amoxicillin Delivery and Modulation of Osteoblast-like Cell Response [0.03%]
银掺杂介孔钙磷酸盐控制阿莫西林释放及调控成骨细胞反应研究
Asmaa M El-Tohamy,Mahmoud T Abo-Elfadl,Mostafa Mabrouk
Asmaa M El-Tohamy
Background: Calcium phosphate (CaP)-based materials are widely used for bone defect repair, but their clinical utility is often limited by insufficient antibacterial activity and a lack of controlled drug-release capability. To address this...
Alexandra Barsan Bujor,Vlad Ghizdovat,Monica Stamate Cretan et al.
Alexandra Barsan Bujor et al.
Background: Oromucosal films are thin polymeric dosage forms designed to hydrate rapidly in the oral cavity and enable local or systemic drug delivery. Their performance depends on coupled processes including wetting, swelling, polymer rela...
Potent Antimicrobial Chloroindium(III) Phthalocyanine Sensitizer Targeting Drug-Resistant Microbes: Physicochemical, Photobiological Validation and DFT Insights [0.03%]
用于靶向耐药微生物的高效抗菌氯化铟(III)酞菁光敏剂：理化、光生物学验证及DFT研究见解
Aleksandra Pawska,Aleksey E Kuznetsov,Marianna Szczepaniak et al.
Aleksandra Pawska et al.
Background/Objectives: An evaluation of the sensitizing properties of chloroindium(III) phthalocyanine complex (InPc) bearing 4-sulfonylphenoxy groups was performed. Methods: The ability to form singlet oxygen under light exposure was asses...
Evaluated Wound Healing Property of Aloe vera-Coated Dextrane Sulfate/Chitosan Nanoparticles Encapsulating Eucalyptus in a Rat Model [0.03%]
包裹尤加利的海藻酸钠/壳聚糖纳米颗粒的伤口愈合性能评价：大鼠模型研究
Ebtesam A Mohamad,Amany M Gad,Rana H Abd El-Rhman et al.
Ebtesam A Mohamad et al.
Background/Objectives: A hydrogel with enhanced therapeutic properties was developed using chitosan, dextran sulfate, and Aloe vera-coated nanoparticles encapsulating eucalyptus extract. Methods: The physicochemical characteristics of the s...
Hybrid Drug Delivery System Designed from Spatiotemporal Hierarchical Controlled-Release Strategy Co-Delivering Rutin and Resveratrol for Coordinated Anti-Tumor Immunotherapy [0.03%]
一种时空分层控制递送策略驱动的杂化药物输送系统协同递送芦丁和白藜芦醇用于肿瘤免疫治疗
Weinan Li,Sisi Yan,Yingying Gao et al.
Weinan Li et al.
Background: The highly heterogeneous and dynamically evolving tumor microenvironment leads to the development of drug resistance and recurrence in traditional therapies. Although immunotherapy demonstrates unique advantages, its clinical ut...
Influence of Fabrication Techniques on the Physicochemical, Textural, Release and Skin Delivery Performance of Polyvinyl Alcohol-Based Transdermal Films Containing Menthol: A Comparative Study [0.03%]
制备方法对含薄荷醇的聚乙烯醇透皮贴剂的理化性质、质地、释放及经皮递药性能的影响：一项比较研究
Gintaras Matulis,Yuliia Maslii,Nataliia Herbina et al.
Gintaras Matulis et al.
Background: Transdermal films are promising dosage forms for controlled delivery of active pharmaceutical ingredients through the skin. Polyvinyl alcohol (PVA)-based matrices are particularly attractive due to their biocompatibility, film-f...
Cold Plasma-Enabled Interface Engineering and In-Situ Functionalization of Printable Feedstocks in Additive Manufacturing: Mechanisms, Materials, and Applications [0.03%]
用于增材制造的冷等离子体界面工程和原位功能性印刷原料加工：机制、材料与应用
Xhoi Xibri,Giuseppe F Racaniello,Brendan Gilmore et al.
Xhoi Xibri et al.
Cold plasma (CP) has emerged as a multifunctional surface engineering technology capable of enabling precise, non-thermal modification of material interfaces, while additive manufacturing (AM) has transformed modern fabrication through a la...
Codonopsis pilosula Lipophilic Extract-Loaded Thermosensitive Nanogel Attenuates Skin Photoaging by Inhibiting the FGFR/PI3K/AKT/mTOR Pathway [0.03%]
红毛五味子脂溶性提取物负载热敏纳米凝胶通过抑制成纤维细胞生长因子受体/磷脂酰肌醇-3激酶/蛋白激酶B/哺乳动物雷帕霉素靶点信号通路缓解皮肤光老化
Jiangtao Zhou,Yuhui Ge,Ran Li et al.
Jiangtao Zhou et al.
Background: Skin photoaging, primarily induced by chronic ultraviolet (UV) radiation exposure, is characterized by dryness, wrinkle formation, pigmentation abnormalities, and reduced skin elasticity, resulting from oxidative stress, inflamm...
Optimization of Therapeutic modRNA Delivery to the Lung for Prevention of Pulmonary Fibrosis [0.03%]
用于预防肺纤维化的治疗性modRNA递送至肺的优化研究
Gayatri Mainkar,Magdalena M Zak,Matteo Ghiringhelli et al.
Gayatri Mainkar et al.
Background/Objectives: Pulmonary fibrosis is a progressive and fatal disease characterized by excessive extracellular matrix deposition and irreversible lung remodeling. Although modified mRNA (modRNA) therapeutics offer a promising strateg...