Curcumin-Loaded Microemulsion Gel: An Optimized and Rheologically Acceptable Formulation with Conducive Dermatokinetics for Topical Breast Cancer Therapy [0.03%]
适合局部乳腺癌治疗的具有优良 dermatokinetics 和可接受流变学性质的微乳化凝胶制剂的优化及其载运姜黄素的研究
Md Abul Barkat,Shakilur Rahman,Harshita Barkat et al.
Md Abul Barkat et al.
Background/Objectives: Breast cancer remains one of the most prevalent malignancies worldwide, highlighting the need for safer and more effective therapeutic strategies. Curcumin has shown considerable anticancer potential; however, its cli...
Structure-Function Relationships in Polysaccharide-Iron Complexes: Molecular Characterization, Acid-Stress Release Stability, and Gastrointestinal Tolerability [0.03%]
多糖铁复合物的结构功能关系：分子特征、酸应激释放稳定性和胃肠耐受性
Xiangqiu Qi,Hongwei Zhu,Xin Yan et al.
Xiangqiu Qi et al.
Background: Polysaccharide-iron complexes (PICs) are widely used oral iron supplements, but their gastrointestinal tolerability varies and remains incompletely understood. As typical non-biological complex drugs (NBCDs), PICs exhibit struct...
Isolation and Characterization of a Novel Marine Peptide, WPN-15, from Walleye Pollock (Gadus chalcogrammus) Tail By-Products and Its Therapeutic Effects Against Atopic Dermatitis [0.03%]
一种新的海洋多肽WPN-15的分离、表征及其对特应性皮炎的治疗作用研究——来源于狭鳕鱼尾副产物
Sung-Gyu Lee,Jin-Woo Hwang,Hyun Kang
Sung-Gyu Lee
Background/Objectives: Atopic dermatitis (AD) is a multifactorial inflammatory skin disorder in which epidermal barrier disruption and dysregulated immune responses drive persistent cutaneous inflammation. Owing to their broad spectrum of b...
Development of Nanosystems Delivering with Eco-Friendly Antibacterial Agents Composed of Zingiber officinale/Alpinia galanga and Gold, as Sustainable Antibiotics [0.03%]
一种新型纳米抗菌给药系统：以金和高良姜/姜为原料的绿色抗菌剂作为可持续抗生素的研究与发展
Rosa M Giráldez-Pérez,Elia M Grueso,Alfonso Carbonero et al.
Rosa M Giráldez-Pérez et al.
Background/Objectives: Green antibacterial synthesis is a natural alternative to chemical methods, aligning with the Sustainable Development Goals by being beneficial to the environment and contributing to new therapies to combat antibiotic...
Engineering Poly(Lactic-co-Glycolic Acid) (PLGA)-Based Microspheres for Controlled Corticosteroid Delivery in Intra-Articular Cartilage [0.03%]
用于关节软骨的皮质类固醇控制传递的聚乳酸-羟基乙酸共聚物(PLGA)微球的设计与工程化
Pamela Rose V Samonte,Noelle K Comolli
Pamela Rose V Samonte
Background: Osteoarthritis (OA), affecting approximately 240 million people worldwide, currently lacks targeted, long-acting therapeutic options. This study investigates how physicochemical properties (i.e., size, surface charge, polydisper...
Hyun-Ouk Kim
Hyun-Ouk Kim
Nanotechnology has evolved from a promising idea to a working element in how we detect and treat disease [...].
Hyun-Ouk Kim
Hyun-Ouk Kim
Nanotechnology has moved from a promising idea to a working part of how we treat disease [...].
Lisa Gherardini,Monia Taranta
Lisa Gherardini
Nanomedicine has profoundly transformed the delivery of therapeutic agents by improving drug pharmacokinetics, protecting labile cargos, and expanding the therapeutic potential of a wide range of molecules [...].
Optimization of Gravity Infusion Protocols for 177Lu-DOTATATE Administration in Peptide Receptor Radionuclide Therapy [0.03%]
优化肽受体放射性核素治疗中177Lu-DOTATATE给药的重力输注方案
Salvatore Grasso,Antonio Varallo,Valeria Gaudieri et al.
Salvatore Grasso et al.
Background: Peptide receptor radionuclide therapy (PRRT) with 177Lu-DOTATATE has become a cornerstone in the management of neuroendocrine tumors (NETs). However, the efficiency of this targeted therapy is highly dependent on the radiopharma...
Electrospun Polymeric Nanofibers Incorporating Brazilian Red Propolis Extract for Wound Dressing Applications [0.03%]
含巴西红蜂胶提取物的电纺聚乙烯醇/壳聚糖纳米纤维伤口敷料的研究
Maria Sirlene Morais,Paulo Augusto Marques Chagas,Gustavo Cardoso da Mata et al.
Maria Sirlene Morais et al.
Background/Objectives: Chronic wounds remain difficult to manage because persistent inflammation, microbial colonization, and excess exudate require dressings that combine structural integrity, bioactivity, antimicrobial performance, and cy...