CEBPB dampens the cuproptosis sensitivity of colorectal cancer cells by facilitating the PI3K/AKT/mTOR signaling pathway [0.03%]
CEBPB通过促进PI3K/AKT/mTOR信号通路减弱结直肠癌细胞的铜死亡敏感性
Tianchen Huang,Yong Zhang,Yachao Wu et al.
Tianchen Huang et al.
Background: Cuproptosis is a novel pathway that differs from other forms of cell death and has been confirmed to be applicable for predicting tumor prognosis and clinical treatment response. However, the mechanism underly...
Clinical outcomes and safety of external beam radiotherapy with extensive intrahepatic targets for advanced hepatocellular carcinoma: A single institutional clinical experience [0.03%]
广泛的肝内靶区的体外放射治疗用于晚期肝细胞癌的临床疗效和安全性：单中心经验报告
Sunmin Park,Chai Hong Rim,Won Sup Yoon
Sunmin Park
Background: This study observed the clinical outcome of radiotherapy to extensive intrahepatic targets for advanced hepatocellular carcinoma (HCC) in a single institution. ...
Henry Lik Yuen Chan
Henry Lik Yuen Chan
Saudi consensus guidance for the diagnosis and management of inflammatory bowel disease in children and adolescents [0.03%]
沙特儿童和青少年炎症性肠病诊断与管理共识意见书
Omar I Saadah,Turki AlAmeel,Ahmed Al Sarkhy et al.
Omar I Saadah et al.
The management of inflammatory bowel disease (IBD) in children and adolescents is challenging. Clear evidence-based guidelines are required for this population. This article provides recommendations for managing IBD in Saudi children and ad...
Stigma in steatotic liver disease: A survey of patients from Saudi Arabia [0.03%]
非酒精性脂肪肝病患者的污名化现象——一项针对沙特阿拉伯患者的调查研究
Saleh A Alqahtani,Khalid Alswat,Mohamed Mawardi et al.
Saleh A Alqahtani et al.
Background: A recent name change of nonalcoholic fatty liver disease (NAFLD) or metabolic dysfunction-associated fatty liver disease (MAFLD) to metabolic dysfunction-associated steatotic liver disease was primarily driven...
The prevalence, severity, and risk factors of erosive esophagitis in a Middle Eastern population [0.03%]
中东地区糜烂性食管炎的流行病学、严重程度和危险因素
Majid Alsahafi,Fatma Salah,Hebah Mimish et al.
Majid Alsahafi et al.
Background: Erosive esophagitis (EE) is frequently present in patients with gastroesophageal reflux disease (GERD), some of which may not have GERD symptoms. The prevalence of EE in the Saudi population is unknown. In thi...
Short term effectiveness of ustekinumab versus vedolizumab in Crohn's disease after failure of anti-TNF agents: An observational comparative study design with a Bayesian analysis [0.03%]
英夫利昔单抗疗效失败的克罗恩病患者短期使用乌司奴单抗与维多珠单抗疗效观察性比较研究及贝叶斯分析
Ahmad Alamer,Lina H Al Lehaibi,Mukhtar Alomar et al.
Ahmad Alamer et al.
Background: Crohn's disease (CD) is a debilitating gastrointestinal disease with complex etiology. Although effective, recipients of anti-tumor necrosis factor (TNF) agents may experience primary or secondary nonresponse,...
Factors associated with precancerous stomach lesions and progresion: A 7-year multi-center prospective cohort study on the low incidence of gastric cancer in central Saudi Arabia [0.03%]
与胃癌前病变相关因素及进展的7年多中心前瞻性队列研究——低发病率沙特阿拉伯中部地区的胃癌案例
Georgios Zacharakis,Amol Dahale,Elsayed R A Abd Elbary et al.
Georgios Zacharakis et al.
Background: In Saudi Arabia (SA) no data are available on precancerous stomach lesions (PSLs) or the associated risk factors. We aimed to identify PSLs and investigate factors associated with PSLs and their progression. ...
Elevated Hepatitis B virus RNA levels in hepatocellular carcinoma patients compared to cirrhotic individuals: A propensity score matched analysis [0.03%]
与肝硬化个体相比，肝癌患者乙型肝炎病毒RNA水平升高：倾向评分匹配分析
Yuying Wang,Juanli Wu,Yushuang Zhang et al.
Yuying Wang et al.
Background: To delineate the levels of serum Hepatitis B virus (HBV) RNA in patients with HBV-related hepatocellular carcinoma (HCC) and study comparisons with those of individuals afflicted with cirrhosis. ...
Risk of perforation related to colorectal endoscopic submucosal dissection: Is this finally predictable? [0.03%]
结肠镜黏膜下剥离术的穿孔风险可以预测了吗？
Alberto Murino,Alessandro Rimondi
Alberto Murino