Probable Mechanism(s) of Antifungal Activity of SJA-95, a Heptaene Polyene Antibiotic [0.03%]
SJA-95(七烯多烯抗生素)抗真菌作用的可能机制
S K Desai,S R Naik
S K Desai
A new strain, streptomyces sp. S. 24 was isolated from a soil sample collected from Japan. The strain produced heptaene polyene antibiotic, SJA-95, in submerged culture and found to elicit promising antifungal activity against yeasts, filam...
Antiinflammatory, analgesic and antipyretic activity of certain thiazolidinones [0.03%]
某些噻唑衍生物的抗炎、镇痛和解热作用
A D Taranalli,A R Bhat,S Srinivas et al.
A D Taranalli et al.
The thiazolidin-4-one derivatives and the corresponding spiro compounds were synthesized from sulphanilamide and were evaluated for anti-inflammatory and analgesic activity in acute and sub acute models. Compounds were also evaluated for an...
3D-QSAR CoMFA study of some Heteroarylpyrroles as Possible Anticandida Agents [0.03%]
某些杂环吡咯类抗真菌化合物的三维定量结构活性关系研究
P C Sharma,S V Sharma,Archana Sharma et al.
P C Sharma et al.
A three dimensional quantitative structure-activity relationship study using the comparative molecular field analysis method was performed on a series of 3-aryl-4-[alpha-(1H-imidazol-1-yl) aryl methyl] pyrroles for their anticandida activit...
V S N M Dwibhashyam,A N Nagappa
V S N M Dwibhashyam
Treating central nervous system diseases is very challenging because of the presence of a variety of formidable obstacles that impede drug delivery. Physiological barriers like the blood-brain barrier and blood-cerebrospinal fluid barrier a...
M B Patel,N A Oza,I S Anand et al.
M B Patel et al.
The liver X receptors alpha and beta are orphan nuclear receptors that are key regulators in maintaining cholesterol homeostasis. Originally they were found to play an important role in reverse cholesterol transport, a pathway for the remov...