Antiulcer Activity of Hydroalchol Extract of Momordica dioica roxb. Fruit [0.03%]
Momordica dioica Roxb.果实的抗溃疡作用研究
M Vijayakumar,M Bavani Eswaran,S K Ojha et al.
M Vijayakumar et al.
The present study was carried out to evaluate antiulcer activity of hydroalcohol extract of Momordica dioica Roxb. fruit. Momordica dioica Roxb. fruit extract (100, 200 and 400 mg/kg body weight) was administered orally, twice daily for 5 d...
Development and Validation of a UV Spectrophotometric Method for the Simultaneous Estimation of Eprosartan Mesylate and Hydrochlorothiazide in Bulk and Formulations [0.03%]
棓塞和氢氯噻嗪原料药及制剂的紫外分光光度法研究与验证
K Anandakumar,D Vijaya Santhi,D Jothieswari et al.
K Anandakumar et al.
A simple, efficient, precise and accurate absorbance ratio method have been developed for the estimation of eprosartan mesylate and hydrochlorothiazide in pure and in fixed dose combination. In this method, UV spectra of eprosartan mesylate...
A Validated HPLC Method for Zanamivir and its Application to In vitro Permeability Study in Caco-2 Culture Model [0.03%]
zanamivir的HPLC测定方法及其在体外Caco-2细胞模型中渗透性研究中的应用
B Boonyapiwat,N Sarisuta,Y Ma et al.
B Boonyapiwat et al.
A simple HPLC method was developed and validated for the quantification of zanamivir in permeability studies using Caco-2 cell culture model. Chromatographic resolution was achieved using 98% (v/v) ultrapure water and 2% (v/v) acetonitrile ...
Development and validation of liquid chromatography-mass spectrometry method for the estimation of rifampicin in plasma [0.03%]
LC-MS法测定血浆中利福平的方法学研究及方法验证
J S Patil,Sarasija Suresh,A R Sureshbabu et al.
J S Patil et al.
A selective, rapid and sensitive liquid chromatography-mass spectrometry method was developed for the quantitative estimation of rifampicin in plasma. With phenacetin as internal standard, sample pretreatment involved a one-step extraction ...
A biochemical study on the gastroprotective effect of andrographolide in rats induced with gastric ulcer [0.03%]
andrographolide对胃溃疡大鼠的胃保护作用的生化研究
P Saranya,A Geetha,S M K Narmadha Selvamathy
P Saranya
The major objective of the study was to evaluate the gastroprotective property of andrographolide, a chief component of the leaves of Andrographis paniculata in terms of the ulcer preventive effect in rats. An acute toxicity test was conduc...
Formulation and development of metered dose inhalations of salbutamol in solution form [0.03%]
盐酸沙丁胺醇溶液型气雾剂的处方和开发研究
Anubha Khale,Amrita Bajaj
Anubha Khale
In the present study attempts were made to prepare metered dose inhalation of salbutamol in solution form and compared it with the marketed metered dose inhalation in suspension form. Solution form of the drug was found better than marketed...
Effects of D-003 on Lipopolysaccharides-induced Osteonecrosis in Rabbits [0.03%]
D-003对脂多糖诱导的兔股骨头坏死的影响
Miriam Noa,M Valle,Sarahí Mendoza et al.
Miriam Noa et al.
D-003, a mixture of high molecular weight acids, inhibits cholesterol synthesis prior to mevalonate and prevents osteoporosis induced by ovariectomy in rats, and both osteoporosis and osteonecrosis induced by corticoids in rats. The aim of ...
Development and validation of new discriminative dissolution method for carvedilol tablets [0.03%]
卡维地洛片的新区分性溶出方法的建立及验证
V Raju,K V R Murthy
V Raju
The objective of the present study was to develop and validate a discriminative dissolution method for evaluation of carvedilol tablets. Different conditions such as type of dissolution medium, volume of dissolution medium and rotation spee...
Improvement of solubility and dissolution properties of clotrimazole by solid dispersions and inclusion complexes [0.03%]
通过固态溶液和包合物改善克霉唑的溶解度和溶出性质
Gehan Balata,M Mahdi,Rania Abu Bakera
Gehan Balata
Solid dispersions of a slightly water-soluble drug, clotrimazole, were prepared in different weight ratios using polyethyleneglycol 4000 and different molecular weight polyvinyl pyrrolidones as carriers. Moreover, binary and ternary β-cycl...
Two Formulations of Venlafaxine are Bioequivalent when Administered as Open Capsule Mixed with Applesauce to Healthy Subjects [0.03%]
两种欣百达的剂型与苹果酱混合口服后的生物等效性：在健康受试者中的研究
Renu T Jain,J Panda,A Srivastava
Renu T Jain
Venlafaxine is a unique antidepressant approved for treatment of various depressive disorders. A single dose, cross-over bioequivalence study was performed with two different formulations of venlafaxine 150 mg extended-release capsules in w...