Ion-activated In Situ Gelling Ophthalmic Delivery Systems of Azithromycin [0.03%]
离子触发的阿奇霉素在眼内凝胶的眼用输送系统
C Vijaya,K Swetha Goud
C Vijaya
Gelation of pectin caused by divalent cations especially calcium ions has been applied to develop an ophthalmic formulation of azithromycin in the present study. Rapid elimination of drug on instillation into cul de sac would be minimal wit...
Preparation and in vitro characterization of mucoadhesive hydroxypropyl guar microspheres containing amlodipine besylate for nasal administration [0.03%]
含有贝那地平的羟丙基 Guar 微球的制备及体外特征研究
N G N Swamy,Z Abbas
N G N Swamy
Amlodipine besylate microspheres for intranasal administration were prepared with an aim to avoid first-pass metabolism, to achieve controlled blood level profiles and to improve therapeutic efficacy. Hydroxypropyl Guar, a biodegradable pol...
Effects of Combination of Thiazolidinediones with Melatonin in Dexamethasone-induced Insulin Resistance in Mice [0.03%]
噻唑烷二酮与褪黑素联合应用对地塞米松致小鼠胰岛素抵抗的影响
M M Ghaisas,Y S Ahire,P R Dandawate et al.
M M Ghaisas et al.
In type 2 Diabetes, oxidative stress plays an important role in development and aggregation of insulin resistance. In the present study, long term administration of the dexamethasone led to the development of insulin resistance in mice. The...
Manisha Bisht,S S Bist
Manisha Bisht
Gout is a metabolic disorder characterized by elevated uric acid levels in the body, associated with painful arthritis, tophi and nephropathy. The most frequently used pharmacologic urate lowering strategies involve reducing urate productio...
Synthesis and Pharmacological Activities of Some New 5-Substituted-2-mercapto-1,3,4-oxadiazoles [0.03%]
一些新的5-取代-2-巯基-1,3,4-恶二唑的合成及其药理活性研究
Shobha R Desai,U Laddi,Rajani S Bennur et al.
Shobha R Desai et al.
In this study, various 5-β-[(N-benzenesulphony/tosyl)-4-(un) substituted anilino]ethyl-2-mercapto-1,3,4-oxadiazole (4a-f), with sulphonamide moiety at the side chain have been synthesised. The structures of the newly synthesised compounds ...
Out-patients Prescriptions are Safe from Drug Interactions or Not: A Pilot Study Report [0.03%]
门诊处方安全吗：用药联合效果试点研究报告
B H Vaidhun,A Sathish
B H Vaidhun
The objective of the research work was to analysis the out patients drug interactions and alerts the healthcare professionals to prevent the future complications. The study was done in three pharmacies within a 200 meters distance of each o...
Synthesis and Antimicrobial Activity of Some New 2-(3-(4-Aryl)-1-phenyl-1H-pyrazol-4-yl) Chroman-4-ones [0.03%]
一些新的2-(3-(4-芳基)-1-苯基-1H-吡唑-4-基)色满-4-酮的合成及其抗菌活性研究
O Prakash,K Hussain,K R Aneja et al.
O Prakash et al.
Seven new 2-(3-(4-aryl)-1-phenyl-1H-pyrazol-4-yl) chroman-4-ones (4a-4g) have been synthesized by cyclization of 2-hydroxychalcone analogues of pyrazole 3a-3g using conc. HCl in acetic acid. The structures of the compounds 4a-4g were establ...
Simultaneous voltammetric determination of nitazoxanide and ofloxacin in pharmaceutical formulation [0.03%]
尿囊素和恶喹酸的药典配方同时伏安测定法
Shital Gandhi,V Mehta,Sadhana Rajput
Shital Gandhi
A simple, sensitive and highly selective electrochemical method was developed for the simultaneous determination of nitazoxanide and ofloxacin in aqueous media (Britton-Robinson buffer, pH-8.36) on a hanging mercury drop electrode (HMDE) us...
Spectrophotometric Determination of Poorly Water Soluble Drug Rosiglitazone Using Hydrotropic Solubilization technique [0.03%]
氢键增溶技术在药物盐酸罗格列酮显色测定中的应用研究
A P Sherje,K J Desai
A P Sherje
In the present investigation, hydrotropic solution of urea was employed as a solubilizing agent for spectrophotometric determination of poorly water-soluble drug rosiglitazone maleate. In solubility determination study, it was found that th...
Development and Validation of a RP-HPLC Method for Estimation of Prulifloxacin in Tablet Dosage Form [0.03%]
制备和验证测定片剂中普卢利夫洛昔辛的RP-HPLC方法
S Singh,U K Singh,R M Singh et al.
S Singh et al.
A simple, precise, rapid, accurate and economic reverse phase high performance liquid chromatographic method has been developed for the estimation of prulifloxacin in tablet dosage form. The separation was achieved by using octadecylsilane ...