Role of Mitochondrial Enzymes and Sarcoplasmic ATPase in Cardioprotection Mediated by Aqueous Extract of Desmodium gangeticum (L) DC Root on Ischemic Reperfusion Injury [0.03%]
Desmodium gangeticum (L) DC根的水提物介导缺血再灌注损伤的心脏保护作用中线粒体酶和肌浆网ATP酶的作用研究
G A Kurian,J Paddikkala
G A Kurian
The present study investigate the protective effect of aqueous root extract of Desmodium gangeticum in preserving mitochondrial and sarcoplasmic ATPase during ischemia reperfusion injury. The isolated rat hearts in both drug and control gro...
B K Satishbabu,V R Sandeep,R B Ravi et al.
B K Satishbabu et al.
A multiple unit oral floating drug delivery system of famotidine was developed to prolong gastric residence time, target stomach mucosa and increase drug bioavailability. Drug and polymer compatibility was studied by subjecting physical mix...
Montmorillonite-Alginate Composites as a Drug delivery System: Intercalation and In vitro Release of Diclofenac sodium [0.03%]
用于载药体系的高岭土-海藻酸钠复合物：吲哚美辛在层间插入及体外释放行为研究
B D Kevadiya,H A Patel,G V Joshi et al.
B D Kevadiya et al.
Diclofenac sodium and alginate was intercalated into montmorillonite to form uniform sized beads by gelation method. The structure and surface morphology of the synthesized composite beads were characterized by powdered X-ray diffraction, F...
Determination of actarit from human plasma for bioequivalence studies [0.03%]
人血浆中アクタリトリル的测定用于生物等效性研究
P Loya,M N Saraf
P Loya
An analytical method based on high-performance liquid chromatography with ultraviolet detection (245 nm) was developed for the determination of actarit in human plasma. Coumarin was used as an internal standard. Chromatographic separation w...
Synthesis and anticonvulsant activity of a new series of 1,4-dihydropyridine derivatives [0.03%]
一类新的1,4-二氢吡啶衍生物的合成及其抗惊厥活性研究
R Surendra Kumar,A Idhayadhulla,A Jamal Abdul Nasser et al.
R Surendra Kumar et al.
A series of 1,4-dihydropyridine derivatives (1a-g) were prepared from three compounds condensation of Hantzsch synthesis. A new series of 2,2'-{[4-(aryl)-2,6-dimethyl-1,4-dihydropyridine-3,5-diyl]dicarbonyl}dihydrazinecarbothioamide (2a-g) ...
Effect of Different Carriers on in vitro Permeation of Meloxicam through Rat Skin [0.03%]
载体类型对美洛昔康体外透皮速率的影响
M A Saleem,Sumanji Bala,Liyakat et al.
M A Saleem et al.
The ability of β-cyclodextrin, hydroxypropyl-β-cyclodextrin, polyvinyl pyrrolidone and urea to influence the percutaneous absorption of meloxicam through isolated rat skin was evaluated. Carrier complex were prepared by kneading method in...
Formulation and evaluation of trimetazidine dihydrochloride extended release tablets by melt congealing method [0.03%]
熔融固化法制备曲美他嗪缓释片及其评价研究
S D Javeer,Reshma Pandit,S P Jain et al.
S D Javeer et al.
Trimetazidine dihydrochloride, a cellular antiischemic agent indicated in the management and prophylaxis of angina pectoris is given as 20 mg thrice daily in the conventional dosage regimen. The purpose of the present study was to formulate...
Evaluation of Antiinflammatory Activity of Centratherum anthelminticum (L) Kuntze Seed [0.03%]
Centratherum anthelminticum (L) Kuntze种子抗炎活性的评价研究
Purnima Ashok,B C Koti,A H M Thippeswamy et al.
Purnima Ashok et al.
In the present study petroleum ether and alcoholic extracts of Centratherum anthelminticum (L) Kuntze seed (100 mg and 200 mg/kg p.o.) were evaluated for antiinflammatory activity in acute and subacute models of inflammation. It was found t...
H Rajpurohit,P Sharma,S Sharma et al.
H Rajpurohit et al.
The colon targeted drug delivery has a number of important implications in the field of pharmacotherapy. Oral colon targeted drug delivery systems have recently gained importance for delivering a variety of therapeutic agents for both local...
R K Khar,G K Jain,M H Warsi et al.
R K Khar et al.
Nucleic acid-based therapeutics have gained a lot of interest for the treatment of diverse ophthalmic pathologies. The first to enter in clinic has been an oligonucleotide, Vitravene(®) for the treatment of cytomegalovirus infection. More ...