Whole-exome sequencing for identification of genetic changes in adult-onset posterior polar cataract [0.03%]
全外显子组测序在成人后极性白内障基因突变筛查中的应用
Anshul Sharma,Namrata Sharma,Tushar Agarwal et al.
Anshul Sharma et al.
Purpose: Posterior polar cataract (PPC), a rare congenital cataract, is characterized by subcapsular opacities in the lens affecting vision and posing surgical challenges. Genetic heterogeneity exists, though several gene...
Amod Gupta
Amod Gupta
Infectious uveitis is a significant cause of ocular morbidity and visual impairment worldwide, especially in developing regions, where it commonly leads to intraocular inflammation. However, in recent years, cases of infectious uveitis have...
Interferon as a novel agent for management of macular edema: Where do we stand? [0.03%]
干扰素治疗玻璃体视网膜疾病的新方法——干扰素诱导蛋白10(abbb)可作为治疗黄斑水肿的新手段吗？
Ankush Kawali,Raj Hirani,Sai Bhakti Mishra et al.
Ankush Kawali et al.
Inflammatory macular edema (IME) is a vision-threatening manifestation of ocular inflammation that arises from diverse causes such as uveitis, postoperative inflammation, and drug-related reactions. Corticosteroids remain the cornerstone of...
Emerging in vitro models of corneal stromal fibrosis: Toward human-relevant platforms for anti-scarring therapeutics [0.03%]
角膜基质纤维化新兴体外模型：用于抗瘢痕治疗的与人相关的平台
Gamze D Can,Mehmet Gurdal,Ozlem B Selver
Gamze D Can
Corneal stromal fibrosis, characterized by the aberrant transformation of keratocytes into contractile, extracellular matrix-secreting myofibroblasts, is a major cause of irreversible visual impairment worldwide. Despite extensive studies i...
Corneal collagen cross-linking at diagnosis in pediatric keratoconus: A prospective study from the Indian Subcontinent [0.03%]
印度次大陆儿童圆锥角膜诊断时的交联治疗：一项前瞻性研究
Ritu Arora,Parul Jain,Trushaa Garg
Ritu Arora
Purpose: To assess the one-year visual, refractive, and tomographic outcomes of corneal collagen cross-linking (CXL) performed at diagnosis in Indian children with keratoconus and to evaluate its safety in eyes with contr...
Outcomes of vitreoretinal interventions in management of perioperative suprachoroidal hemorrhage [0.03%]
玻璃体视网膜手术治疗围手术期前房下出血的预后
Vidhi Bajpai,Rajeev R Pappuru,Vivek P Dave et al.
Vidhi Bajpai et al.
Purpose: To report visual and anatomical outcomes of vitreoretinal interventions in perioperative suprachoroidal hemorrhage (SCH). Methods: ...
Clinico-demographic profile and management outcomes of periocular and subconjunctival dirofilariasis in South India [0.03%]
印度南部眼睑和结膜下 дирофilaria 病的临床人口学特征及治疗结果
Shebin Salim,Marian Pauly,Mekhla Naik et al.
Shebin Salim et al.
Purpose: To report the clinico-demographic profile and management outcomes of periocular and subconjunctival dirofilariasis. Design: Re...
Genetic and network evidence that coffee-derived 7-methylxanthine mitigates myopia via the EPHB4 axis [0.03%]
基因和网络证据表明咖啡衍生物7-甲基黄嘌呤通过EPHB4轴缓解近视
Mozi Chen,Jie Zheng,Yan Lin et al.
Mozi Chen et al.
Purpose: To evaluate the causal effects of coffee-related circulating biomarkers on myopia and to nominate plausible biological mechanisms. Design: ...
Ferroptosis in retinal pigment epithelial cells: Current status and future developments [0.03%]
视网膜色素上皮细胞铁死亡研究现状及未来展望
Wen Liu,Wenwen Li,Dan Wang et al.
Wen Liu et al.
Retinal pigment epithelial (RPE) cells play a crucial role in maintaining the normal function of the retina. In recent years, research on ferroptosis-a novel iron-dependent form of cell death-in RPE cells has gradually attracted attention. ...
Anti-VEGF safety in evolution: A comprehensive review of ocular and systemic considerations [0.03%]
抗VEGF药物的安全性演变：全面回顾眼部和全身因素的考量
Ramesh Venkatesh,Preksha Biradar,Gaurav Malwe et al.
Ramesh Venkatesh et al.
Intravitreal anti-vascular endothelial growth factor (VEGF) therapy has transformed the management of retinal and choroidal vascular diseases, delivering substantial and sustained visual benefits across neovascular age-related macular degen...