Examination of the role of magnetic resonance imaging in multiple sclerosis: A problem-orientated approach [0.03%]
磁共振在多发性硬化病中的作用分析：以问题为导向的方法学研究
Henry F McFarland
Henry F McFarland
Magnetic Resonance Imaging (MRI) has brought in several benefits to the study of Multiple Sclerosis (MS). It provides accurate measurement of disease activity, facilitates precise diagnosis, and aid in the assessment of newer therapies. The...
Kottil W Rammohan
Kottil W Rammohan
Background: Technological advances have made it possible to examine the human cerebrospinal fluid (CSF) in a manner that was previously impossible. CSF provides a window into the changes that occur in the central nervous ...
Pediatric multiple sclerosis [0.03%]
儿童多发性硬化症
Yashma Patel,Vikram Bhise,Lauren Krupp
Yashma Patel
Pediatric multiple sclerosis (MS) represents a particular MS subgroup with unique diagnostic challenges and many unanswered questions. Due to the narrow window of environmental exposures and clinical disease expression, children with MS may...
Anu Jacob
Anu Jacob
Neuromyelitis optica is an inflammatory demyelinating disorder of the central nervous system. The discovery of a specific antibody (NMO IgG /aquaporin-4 antibody) in patients with this condition has led to a marked revival of research on th...
Barrie J Hurwitz
Barrie J Hurwitz
The diagnosis of multiple sclerosis (MS) requires objective findings referable to the central nervous system. A wide differential diagnosis often has to be considered. Magnetic resonance imaging and electrophysiologic and cerebrospinal flui...
Kathleen Hawker
Kathleen Hawker
B cells have recently been identified as an integral component of the immune system; they play a part in autoimmunity through antigen presentation, antibody secretion, and complement activation. Animal models of multiple sclerosis (MS) sugg...
Michael K Racke
Michael K Racke
Multiple sclerosis (MS) is a suspected autoimmune disease in which myelin-specific CD4+ and CD8+ T cells enter the central nervous system (CNS) and initiate an inflammatory response directed against myelin and other components of the CNS. A...
Stephen Sawcer
Stephen Sawcer
THE EPIDEMIOLOGY OF MULTIPLE SCLEROSIS HAS BEEN EXTENSIVELY INVESTIGATED AND TWO FEATURES HAVE CONSISTENTLY EMERGED: marked geographical variation in prevalence and substantial familial clustering. At first sight, geographic variation would...
Kottil W Rammohan
Kottil W Rammohan
Sanjeev V Thomas
Sanjeev V Thomas