Current diagnostic approach to fungal infection in the critically ill patient [0.03%]
重症患者真菌感染的当前诊断方法
Alfredo Maldonado-Barrueco,Inmaculada Quiles-Melero,Julio García-Rodríguez
Alfredo Maldonado-Barrueco
Invasive fungal infections are a major cause of morbidity and mortality in critically ill patients, with an increasing global incidence and species diversity, especially after the SARS-CoV-2 pandemic. Diagnosis relies on a combination of cl...
Syndromic platforms in the management of infection in the critically ill patient: test indication and diagnostic interpretation [0.03%]
重症感染患者的综合征平台管理：检测指征和诊断解读
Sara Sanz,Natalia Burillo,Juan Manuel García-Lechuz
Sara Sanz
The timely and appropriate administration of empirical antibiotic therapy is critical for patient survival. However, several studies suggest that approximately 20-30% of patients presenting with sepsis receive inadequate antibiotic treatmen...
Emilia Cercenado,Francisco Javier Candel
Emilia Cercenado
This non-exhaustive minireview describes the main characteristics of the new beta-lactamase inhibitors (enmetazobactam, avibactam, relebactam, durlobactam, zidebactam, nacubactam, vaborbactam, taniborbactam, and xeruborbactam), their spectr...
Diagnostic stewardship in sepsis: minding the gap from the microbiology lab to ward [0.03%]
脓毒症诊断中的精准治疗：微生物实验室和临床之间的差距不容忽视
Rafael Canton,Ana Verónica Halperín
Rafael Canton
Sepsis is a life-threatening condition resulting from the body's dysregulated response to infection that demands timely diagnosis and effective antimicrobial treatment to reduce mortality and healthcare burden. Microbiology laboratories pla...
Usefulness of monocyte distribution width (MDW) in enhancing diagnostic accuracy of infection among severely ill patients presenting to the emergency department [0.03%]
急诊科严重患者单核细胞分布宽度（MDW）对感染诊断价值的研究
Juan González Del Castillo,Enrique Del Toro,Marcos Fragiel et al.
Juan González Del Castillo et al.
Sepsis remains a major cause of morbidity and mortality and continues to pose substantial diagnostic challenges in its early stages. Monocyte Distribution Width (MDW), a parameter automatically integrated into complete blood counts by next-...
Introduction to XIV updating course of antimicrobials and infectious diseases [0.03%]
第十四届抗菌药物和传染病更新课程介绍
Francisco Javier Candel,Mayra Matesanz
Francisco Javier Candel
[Ziresovir: a potent, selective, and oral inhibitor of the respiratory syncytial virus fusion (F) protein] [0.03%]
[扎利斯韦尔：一种强有力的、选择性的呼吸道合胞病毒融合(F)蛋白口服抑制剂]
Jordi Reina,Juan Bosch-Durán
Jordi Reina
In 2023, a monoclonal antibody (niservimab) specifically targeting the "zero site (Φ)" of the prefusion form of the RSV F protein was marketed in Spain. Various studies have demonstrated its high efficacy in preventing hospitalization and ...
Pedro Puerta-Alcalde,Jesús Guinea,Emilio Maseda et al.
Pedro Puerta-Alcalde et al.
Intra-abdominal candidiasis, which includes Candida peritonitis and Candida produced intra-abdominal abscesses, accounts for 10-30% of all intra-abdominal infections diagnosed in the intensive care units. Intra-abdominal candidiasis is asso...
Risk model derivation and clinical outcomes in COVID-19 pneumonia patients discharged from the emergency department [0.03%]
新冠肺炎急诊出院患者的危险因素模型及临床结局分析
Francisco Javier Martín-Sánchez,Sara Laínez-Martínez,Pedro López-Ayala et al.
Francisco Javier Martín-Sánchez et al.
Objectives: To develop and validate a clinical model to predict 30-day mortality in high-risk COVID-19 patients evaluated in the Emergency Department, and to evaluate outcomes in adults with COVID-19 pneumonia classified ...
Chronic lung infection by Achromobacter xylosoxidans in a patient with cystic fibrosis successfully treated with cefiderocol as a pre and post-lung transplant regimen [0.03%]
卡博莫巴菌慢性肺感染的囊性纤维化患者术前和术后成功应用头孢狄罗治疗案例报告
Susana Ramos-Oliveira,Rodrigo Alonso-Moralejo,Virginia Pérez et al.
Susana Ramos-Oliveira et al.