A clinically relevant reinterpretation of disk approximation testing for inducible AmpC in Pseudomonas aeruginosa [0.03%]
解释铜绿假单胞菌诱导型AmpC盘区实验的临床意义
Arturo Reyes-Gualito,Luis Raúl Rivera-Garay,Azyadeh Cobo-Alva et al.
Arturo Reyes-Gualito et al.
Introduction: Current antimicrobial susceptibility methods fail to capture the variability of AmpC induction pathways in Pseudomonas aeruginosa. This leads to preventable errors in ceftazidime susceptibility reporting. We...
Ángel Gil-de-Miguel,José Antonio Navarro-Alonso,María Pilar Arrazola-Martínez et al.
Ángel Gil-de-Miguel et al.
Despite progress in adult vaccination schedules, coverage rates remain suboptimal in Spain. This opinion paper, authored by a multidisciplinary group of experts, analyzes the causes and consequences of adult undervaccination, covering clini...
María José Núñez Orantos
María José Núñez Orantos
This manuscript summarizes the most relevant publications and international conference presentations on HIV infection between 2022 and 2024. It provides updated epidemiological data on HIV in Spain and assesses healthcare professionals' kno...
New evidence in the management of CMV infection: impact on prophylaxis and treatment [0.03%]
CMV感染的管理新证据：对预防和治疗的影响
Jesús Fortún
Jesús Fortún
Cytomegalovirus (CMV) infection is a leading cause of morbidity and mortality among immunocompromised individuals, especially hematopoietic stem cell transplant and solid organ transplant recipients. In recent years, significant advances ha...
Legends, dogmas, presumptions, and demystifications in antibiotic therapy [0.03%]
抗生素治疗中的传说、教条、臆想和去神秘化
Rosa Blanes Hernández,Santiago de Cossio Tejido,Francesc Puchades Gimeno et al.
Rosa Blanes Hernández et al.
Suboptimal antimicrobial use is a global challenge driven by entrenched misconceptions and dogmas. This article aims to critically evaluate and debunk several widespread myths in infectious disease management that lead to overdiagnosis and ...
Therapeutic approach in the critically ill patient with suspected multidrug resistance [0.03%]
多重耐药患者危重病人的治疗方案
María Cruz Soriano-Cuesta,Marina López-Olivencia,Francisco Javier Candel et al.
María Cruz Soriano-Cuesta et al.
The treatment of infections caused by multidrug-resistant microorganisms (MDROs) in critically ill patients remains a major clinical challenge due to the high mortality associated with therapeutic failure. Delays in administering effective ...
Emilio Maseda,Alejandro Suárez-de la Rica
Emilio Maseda
This document focuses on the different aspects to be considered in order to improve the management of nosocomial peritonitis, particularly the changes in the epidemiology of causative microorganisms and the increasing emergence of pathogens...
Therapeutic optimization against bacteria carrying metalloenzymes: the battle for class B [0.03%]
针对金属酶耐药菌的治疗优化：B类β-内酰胺酶之战
Manuel Pina-Sánchez,Marta Rua,Francisco Javier Candel et al.
Manuel Pina-Sánchez et al.
The spread of metallo-β-lactamases (MBL)-producing Gram-negative bacilli represents a global health challenge, associated with increased mortality rates. The prevalence of MBL-producing isolates, particularly of New Delhi metallo-β-lactam...
Montserrat Rodríguez-Aguirregabiria
Montserrat Rodríguez-Aguirregabiria
Nosocomial pneumonia is one of the most common nosocomial infections and is associated with significant clinical and economic burdens, such as long-term hospitalization, high medical costs, and increased morbidity and mortality. The increas...
Comprehensive approach to primary immunodeficiencies in adulthood: recognition and diagnosis [0.03%]
成人原发性免疫缺陷的综合诊治策略：识别与诊断
Laura Muñoz-Echeverria,Juan Gabriel Sánchez-Cano,Juan Emilio Losa-García
Laura Muñoz-Echeverria
Primary immunodeficiencies, now referred to as inborn errors of immunity (IEI), are increasingly recognized in adults, not only in the pediatric population. In adults, they may present with recurrent, severe, or unusual infections, but also...