Clinical relevance of the characterisation and quantification of CD8+ T-cell infiltration in high-grade serous ovarian carcinoma using machine learning-based image analysis of dual immunostaining [0.03%]
基于机器学习图像分析的双重免疫组化在高级别浆液性卵巢癌中表征和量化CD8⁺T细胞浸润的临床意义
Jesús Machuca-Aguado,Carmen Alfonso-Rosa,Alejandro Muñoz-Álvarez et al.
Jesús Machuca-Aguado et al.
Introduction: High-grade serous carcinoma (HGSC) is the most common and aggressive subtype of ovarian cancer. Although tumour stage and complete cytoreduction are key prognostic factors, the tumour immune microenvironment...
Lymphomatoid papulosis: A challenge in the differential diagnosis of ulcerative lesions of the oral mucosa [0.03%]
淋巴样乳头状病：口腔黏膜溃疡性病变鉴别诊断中的挑战
Henar Anadón Valero,Lucas Andreu Roche,Sara Navarro Júlvez et al.
Henar Anadón Valero et al.
Lymphomatoid papulosis (LyP) is a primary cutaneous CD30+ lymphoproliferative disorder, with a higher incidence in males. Despite its benign and self-resolving clinical course, it exhibits histological features that may mimic other conditio...
Initial evaluation of the effectiveness of a new eco-friendly staining method: Purple corn-eosin staining [0.03%]
新型环保染色方法的初步评估：紫玉米-伊红染色法
Gian Carlos Ramirez Ubillus,José Sereno Aliaga,Mercedes Bravo Taxa et al.
Gian Carlos Ramirez Ubillus et al.
Objective: To determine the intertest agreement in the histopathological diagnosis using a new eco-friendly staining method, purple corn-eosin, compared with routine haematoxylin-eosin (H&E) staining. ...
Opportunistic identification of Li-Fraumeni syndrome through germline TP53 variant detection from routine tumour next-generation sequencing: An analysis of 1394 cases [0.03%]
通过从常规肿瘤下一代测序中鉴定错义TP53变异筛查李-弗拉梅尼综合征：1394例分析
Svetlana Shalygina,Artemio Payá Romá,Alejandro Garzón Arana et al.
Svetlana Shalygina et al.
Background and objective: Evaluation of a hybrid strategy (bioinformatics and clinical) for detecting germline pathogenic variants in TP53 from routine tumour NGS, addressing clonal haematopoiesis of indeterminate potenti...
Squamoid eccrine ductal carcinoma: A case report and review of the literature [0.03%]
鳞状汗管导管癌：1例报告及文献复习
Laura López-Solache,María Blanco-Bellas,Adrián Santiago López-Caamaño et al.
Laura López-Solache et al.
Squamoid eccrine ductal carcinoma (SEDC) is an extremely rare malignant cutaneous tumour that predominantly affects elderly Caucasian individuals, most commonly involving the head and neck region. Its most characteristic feature is a biphas...
Development and validation of a CNN model for grading oral epithelial dysplasia [0.03%]
深度学习CNN模型辅助口腔上皮内瘤变分级诊断的开发和验证
Chetan Belaldavar,Punnya V Angadi,Uma Mudenagudi et al.
Chetan Belaldavar et al.
Background: Diagnosis of oral epithelial dysplasia (OED), particularly grading, is challenging as it shows inter- and intra-observer variability. New technologies to assist pathologists are needed to decrease variability ...
Diagnostic sensitivity: Surgical biopsy versus minimally invasive techniques in bronchopulmonary cancer [0.03%]
肺癌诊断敏感性：外科活检与微创技术的比较
Denisa-Gabriela Ion-Andrei,Elena Mocanu,Sergiu Chirila et al.
Denisa-Gabriela Ion-Andrei et al.
Introduction and objectives: Lung cancer remains the leading cause of cancer-related mortality, with early diagnosis critical to prognosis and survival. Histopathological confirmation is achieved through invasive or minim...
Holopath-VR360-degree virtual reality videos in pathology education: The Holopath-VR experience [0.03%]
Holopath-VR：病理学教育的360度虚拟现实视频：Holopath-VR体验
Eduardo Alcaraz-Mateos,Isabel Abellan-Leante,Franco Stefano Galdame et al.
Eduardo Alcaraz-Mateos et al.
Introduction: Virtual reality (VR) allows individuals to have immersive experiences that may benefit medical education. The aim of this study was to evaluate the perception of undergraduate medical students when exposed t...
SEAP-GETNE consensus on prognostic and predictive molecular biomarkers in thyroid cancer [0.03%]
东南亚甲状腺癌预后和预测分子生物标志物共识（SEAP-GETNE）
Ignacio Ruz-Caracuel,Teresa Alonso-Gordoa,Susana Hernández et al.
Ignacio Ruz-Caracuel et al.
Thyroid cancer is the most common endocrine malignancy and generally carries a favourable prognosis. However, a subset of cases exhibits aggressive behaviour, metastatic potential, and resistance to conventional therapies. The 2022 WHO clas...
Time as a measure of workload in Anatomical Pathology: Implications for human resource management [0.03%]
时间作为解剖病理工作量的衡量标准：对人力资源管理的影响
Francesc Tresserra,Antonio Martínez Lorente
Francesc Tresserra