The diagnostic and prognostic utility of engrailed homeobox 1 and MYB immunohistochemical expression in the differentiation of salivary gland adenoid cystic carcinoma from its mimics [0.03%]
ENGRAL和MYB免疫组化在涎腺腺样囊性癌鉴别诊断中的作用
Manar Moustafa,Nehal Gamal Elsayed,Ahmad Barakat Waley et al.
Manar Moustafa et al.
Background: Adenoid cystic carcinoma (AdCC) of the salivary glands is an aggressive tumour that can resemble other basaloid or biphasic neoplasms, particularly when only focally represented. We evaluated the diagnostic an...
Early mycosis fungoides: Integrating clinical, histopathological and molecular insights to improve diagnosis and risk stratification [0.03%]
早期蕈样霉菌病：整合临床、病理和分子见解以改善诊断和风险分层
Marcos Rebollo-González,Juan Torre-Castro,Marta Rodríguez et al.
Marcos Rebollo-González et al.
Mycosis fungoides (MF) remains a diagnostic challenge in its early stages, due to its ability to mimic common inflammatory dermatoses and the subtlety of its histopathological features. This review integrates recent advances in anatomical p...
A cross-sectional study on the expression of CD44 as a stem cell marker in breast cancer patients: Association with clinicopathological prognostic markers across molecular subtypes [0.03%]
乳腺癌患者中CD44作为干细胞标志物表达的横断面研究：与分子亚型全程病理预后标志物的关系
Amita Krishnappa,Hrushikesh Kanakapura Paramesh,Ramya Suresh et al.
Amita Krishnappa et al.
The clinical application of cancer stem cell marker CD44 in breast cancer prognosis has been widely explored. However, data on the association between CD44 expression and prognostication across molecular subtypes of breast cancer remain lim...
Expert practical recommendations for optimising tumour and germline testing of homologous recombination repair gene mutations in metastatic prostate cancer [0.03%]
关于转移性前列腺癌同源重组修复基因突变肿瘤和胚系检测的专家实用建议
Pilar González-Peramato,Eugenia García-Fernández,Ana Jambrina et al.
Pilar González-Peramato et al.
With the approval of PARP inhibitors (PARPi), both as monotherapy and in combination with androgen receptor signalling inhibitors (ARSi), for metastatic castration-resistant prostate cancer (mCRPC) and their rapid development in earlier dis...
Uterine intravascular adenomyomatosis: Clinicopathological features and literature review of a rare entity [0.03%]
子宫血管内腺肌瘤样病灶的临床病理特征及文献回顾
Alfonso Agüera-Sanchez,Almudena Peces-Rama,María Amparo Torroba-Carón et al.
Alfonso Agüera-Sanchez et al.
Background: Intravascular adenomyomatosis (IA), characterised by endometrial-type glands or stroma embedded within smooth muscle tissue inside myometrial vessels, is a rare variant within the spectrum of uterine intraveno...
Current perspectives on neurodegenerative diseases: from clinical autopsy to precision medicine [0.03%]
神经退行性疾病的精准医学之路——从临床尸检开始
Alberto Rábano
Alberto Rábano
When it is not cancer: Cystic neutrophilic granulomatous mastitis masquerading as carcinoma [0.03%]
不是癌症时的情况：类癌样囊性中性粒细胞增生性肉芽肿性乳腺炎
Kenza Oqbani,Abderrahmane Ibenyahia,Mohammed Tbouda et al.
Kenza Oqbani et al.
Cystic neutrophilic granulomatous mastitis (CNGM) is a rare inflammatory breast disease that can clinically and radiologically mimic breast carcinoma. Accurate histological diagnosis is essential to prevent unnecessary treatment and guide a...
Clinical relevance of the characterisation and quantification of CD8+ T-cell infiltration in high-grade serous ovarian carcinoma using machine learning-based image analysis of dual immunostaining [0.03%]
基于机器学习图像分析的双重免疫组化在高级别浆液性卵巢癌中表征和量化CD8⁺T细胞浸润的临床意义
Jesús Machuca-Aguado,Carmen Alfonso-Rosa,Alejandro Muñoz-Álvarez et al.
Jesús Machuca-Aguado et al.
Introduction: High-grade serous carcinoma (HGSC) is the most common and aggressive subtype of ovarian cancer. Although tumour stage and complete cytoreduction are key prognostic factors, the tumour immune microenvironment...
Lymphomatoid papulosis: A challenge in the differential diagnosis of ulcerative lesions of the oral mucosa [0.03%]
淋巴样乳头状病：口腔黏膜溃疡性病变鉴别诊断中的挑战
Henar Anadón Valero,Lucas Andreu Roche,Sara Navarro Júlvez et al.
Henar Anadón Valero et al.
Lymphomatoid papulosis (LyP) is a primary cutaneous CD30+ lymphoproliferative disorder, with a higher incidence in males. Despite its benign and self-resolving clinical course, it exhibits histological features that may mimic other conditio...
Initial evaluation of the effectiveness of a new eco-friendly staining method: Purple corn-eosin staining [0.03%]
新型环保染色方法的初步评估：紫玉米-伊红染色法
Gian Carlos Ramirez Ubillus,José Sereno Aliaga,Mercedes Bravo Taxa et al.
Gian Carlos Ramirez Ubillus et al.
Objective: To determine the intertest agreement in the histopathological diagnosis using a new eco-friendly staining method, purple corn-eosin, compared with routine haematoxylin-eosin (H&E) staining. ...