High-sensitivity troponin in the prognosis of patients hospitalized in intensive care for COVID-19: a Latin American longitudinal cohort study [0.03%]
高敏肌钙蛋白在COVID-19重症监护病房住院患者预后中的作用：拉丁美洲纵向队列研究
John Sprockel,Anggie Murcia,Juan Rincon et al.
John Sprockel et al.
Objective: The current study assessed the prevalence of troponin elevation and its capacity to predict 60day mortality in COVID-19 patients in intensive care. ...
A nationwide survey on health resources and clinical practices during the early COVID-19 pandemic in Brazil [0.03%]
巴西在2019冠状病毒病疫情初期的卫生资源和临床实践全国调查
Pedro Paulo Zanella do Amaral Campos,Guilherme Martins de Souza,Thais Midega et al.
Pedro Paulo Zanella do Amaral Campos et al.
Objective: To evaluate clinical practices and hospital resource organization during the early COVID-19 pandemic in Brazil. Methods: Thi...
Hemodynamic phenotype-based, capillary refill time-targeted resuscitation in early septic shock: The ANDROMEDA-SHOCK-2 Randomized Clinical Trial study protocol [0.03%]
基于血流动力学表型和毛细血管再充盈时间导向复苏的早期感染性休克患者的ANDROMEDA-SHOCK-2 随机临床试验方案
Eduardo Kattan,Jan Bakker,Elisa Estenssoro et al.
Eduardo Kattan et al.
Background: Early reversion of sepsis-induced tissue hypoperfusion is essential for survival in septic shock. However, consensus regarding the best initial resuscitation strategy is lacking given that interventions design...
Statistical analysis of a cluster-randomized clinical trial on adult general intensive care units in Brazil: TELE-critical care verSus usual Care On ICU PErformance (TELESCOPE) trial [0.03%]
巴西成人普通重症监护病房群随机临床试验的统计分析：远程重症监护与常规护理对ICU性能影响的对比（TELESCOPE）试验
Otavio Ranzani,Adriano José Pereira,Maura Cristina Dos Santos et al.
Otavio Ranzani et al.
Objective: The TELE-critical Care verSus usual Care On ICU PErformance (TELESCOPE) trial aims to assess whether a complex telemedicine intervention in intensive care units, which focuses on daily multidisciplinary rounds ...
Randomized Controlled Trial
Revista Brasileira de terapia intensiva. 2022 Jan-Mar;34(1):87-95. DOI:10.5935/0103-507x.20220003-pt 2022
Antivirals for adult patients hospitalized with SARS-CoV-2 infection: A randomized, Phase II/III, multicenter, placebo-controlled, adaptive study, with multiple arms and stages. COALITION COVID-19 BRAZIL IX - REVOLUTIOn: protocol and statistical analysis plan [0.03%]
住院成人SARS-CoV-2感染患者的抗病毒药物治疗：一项适应性、多分支分期的随机II/III期多中心双盲安慰剂对照研究：巴西COALITION COVID-19 IX-REVOLUTIOn方案及统计分析计划
Israel Silva Maia,Aline Marcadenti,Fernando Godinho Zampieri et al.
Israel Silva Maia et al.
Repurposed drugs are important in resource-limited settings because the interventions are more rapidly available, have already been tested safely in other populations and are inexpensive. Repurposed drugs are an effective solution, especial...
Valproate-associated hyperammonemic encephalopathy in subarachnoid hemorrhage: a diagnosis to consider [0.03%]
蛛网膜下腔出血伴丙戊酸引起的血氨升高性脑病：一种需要考虑的诊断类型
Vivian Fuellis,Pedro Grille,Federico Verga et al.
Vivian Fuellis et al.
Subarachnoid hemorrhage is a prevalent disease with high morbidity and mortality. Numerous complications contribute to brain injury and defy the clinical practitioner on diagnosis and management. Valproate-associated hyperammonemic encephal...
Rationale and limitations of the SpO2/FiO2 as a possible substitute for PaO2/FiO2 in different preclinical and clinical scenarios [0.03%]
氧合指数(SpO2/FiO2)在不同临床和前期研究场景中替代(O2/FiO2)的理论依据和局限性分析
Eduardo Butturini de Carvalho,Thiago Ravache Sobreira Leite,Raquel Ferreira de Magalhães Sacramento et al.
Eduardo Butturini de Carvalho et al.
Although the PaO 2/FiO 2 derived from arterial blood gas analysis remains the gold standard for the diagnosis of acute respiratory failure, the SpO2/FiO2 has been investigated as a potential substitute. The current narrative review presents...
Brazilian Guidelines for the pharmacological treatment of patients hospitalized with COVID-19: Joint guideline of Associação Brasileira de Medicina de Emergência, Associação de Medicina Intensiva Brasileira, Associação Médica Brasileira, Sociedade Brasileira de Angiologia e Cirurgia Vascular, Sociedade Brasileira de Infectologia, Sociedade Brasileira de [0.03%]
巴西住院COVID-19患者的药理治疗指南：巴西急诊医学协会、巴西重症医学会、巴西医学会、巴西血管病学和外科协会、巴西感染病学分会联合制定指南
Maicon Falavigna,Cinara Stein,José Luiz Gomes do Amaral et al.
Maicon Falavigna et al.
Objective: Several therapies are being used or proposed for COVID-19, and many lack appropriate evaluations of their effectiveness and safety. The purpose of this document is to develop recommendations to support decision...
Perception of professionals in critical patient units about brain death [0.03%]
重症监护病房医务人员对脑死亡的认知调查研究
Neide da Silva Knihs,Sibele Maria Schuantes Paim
Neide da Silva Knihs
The use of a noninvasive intracranial pressure monitoring method in the intensive care unit to improve neuroprotection in postoperative cardiac surgery patients after extracorporeal circulation [0.03%]
一种在重症监护病房使用的非侵入性颅内压监测方法，可改善体外循环心脏术后患者的神经保护措施
Salomón Soriano Ordinola Rojas,Amanda Ayako Minemura Ordinola,Viviane Cordeiro Veiga et al.
Salomón Soriano Ordinola Rojas et al.
Brain injury caused by extracorporeal circulation during cardiovascular surgical procedures has been a recurring complication since the implementation of extracorporeal circulation five decades ago. There is no unique cause of brain injury ...