Awake surgery between art and science. Part I: clinical and operative settings [0.03%]
艺术与科学之间的清醒开颅手术(上):临床和外科设置
Andrea Talacchi,Barbara Santini,Francesca Casagrande et al.
Andrea Talacchi et al.
Awake surgery requires coordinated teamwork and communication between the surgeon and the anesthesiologist, as he monitors the patient, the neuroradiologist as he interprets the images for intraoperative confirmation, and the neuropsycholog...
Jonathan D Clayden
Jonathan D Clayden
Magnetic resonance imaging (MRI) is a flexible and widely available neuroimaging technique. Structural MRI and diffusion MRI, in particular, provide information about connectivity between brain regions which may be combined to obtain a pict...
Andrea Calimera,Enrico Macii,Massimo Poncino
Andrea Calimera
Understanding how the brain manages billions of processing units connected via kilometers of fibers and trillions of synapses, while consuming a few tens of Watts could provide the key to a completely new category of hardware (neuromorphic ...
Alberto Redolfi,Paolo Bosco,David Manset et al.
Alberto Redolfi et al.
The brain of a patient with Alzheimer's disease (AD) undergoes changes starting many years before the development of the first clinical symptoms. The recent availability of large prospective datasets makes it possible to create sophisticate...
The connectomics challenge [0.03%]
连接组学的挑战
Ludovico Silvestri,Leonardo Sacconi,Francesco Saverio Pavone
Ludovico Silvestri
One of the most fascinating challenges in neuroscience is the reconstruction of the connectivity map of the brain. Recent years have seen a rapid expansion in the field of connectomics, whose aim is to trace this map and understand its rela...
Egidio DAngelo,Sergio Solinas,Jesus Garrido et al.
Egidio DAngelo et al.
Realistic modeling is a new advanced methodology for investigating brain functions. Realistic modeling is based on a detailed biophysical description of neurons and synapses, which can be integrated into microcircuits. The latter can, in tu...
Henry Markram
Henry Markram
Although twenty-first century neuroscience is a major scientific enterprise, advances in basic research have not yet translated into benefits for society. In this paper, I outline seven fundamental challenges that need to be overcome. First...
Egidio DAngelo
Egidio DAngelo
Pure akinesia: a kinematic analysis in a case responsive to rotigotine [0.03%]
纯运动不能症的动能分析及罗替戈汀治疗反应的一项研究报告
R Di Fabio,M Serrao,F Pierelli et al.
R Di Fabio et al.
A patient with pure akinesia is described. This rare gait disorder, poorly responsive to therapy, is characterized by gait impairment which may be associated with handwriting and speech difficulties, in the absence of further signs of extra...