Watching the walk: observing chemo-mechanical coupling in a processive myosin motor [0.03%]
观察行走：在一个进程肌球蛋白发动机中观察化学机械耦合现象
Enrique M De La Cruz,Adrian O Olivares
Enrique M De La Cruz
Molecular motors are cellular nanomachines that convert the energy from nucleotide binding, hydrolysis, and product release into mechanical work. Because molecular motors contribute to fundamental processes in all living organisms, includin...
Vocal tract resonances in speech, singing, and playing musical instruments [0.03%]
发声、演唱及演奏乐器时声道共振的作用
Joe Wolfe,Maëva Garnier,John Smith
Joe Wolfe
IN BOTH THE VOICE AND MUSICAL WIND INSTRUMENTS, A VALVE (VOCAL FOLDS, LIPS, OR REED) LIES BETWEEN AN UPSTREAM AND DOWNSTREAM DUCT: trachea and vocal tract for the voice; vocal tract and bore for the instrument. Examining the structural simi...
Liqing Zhang,Layne T Watson
Liqing Zhang
This paper extends previous work on the Darwinian evolutionary fitness effect of the fixation of deleterious mutations by incorporating compensatory mutations, which are mutations (deleterious by themselves) that ameliorate other deleteriou...
Throwing a glance at the neural code: rapid information transmission in the visual system [0.03%]
一瞥神经编码：视觉系统中的快速信息传递
Tim Gollisch
Tim Gollisch
Our visual system can operate at fascinating speeds. Psychophysical experiments teach us that the processing of complex natural images and visual object recognition require a mere split second. Even in everyday life, our gaze seldom rests f...
Ruth E Baker,Santiago Schnell
Ruth E Baker
Since the discovery of gene products oscillating during the formation of vertebral segments, much attention has been directed toward eluciating the molecular basis of the so-called segmentation clock. What research has told us is, that even...
Forward locomotion of the nematode C. elegans is achieved through modulation of a single gait [0.03%]
秀丽隐杆线虫C. elegans的前进运动是通过调节单一步态实现的
Stefano Berri,Jordan H Boyle,Manlio Tassieri et al.
Stefano Berri et al.
The ability of an animal to locomote through its environment depends crucially on the interplay between its active endogenous control and the physics of its interactions with the environment. The nematode worm Caenorhabditis elegans serves ...
Elizabeth H C Bromley,Nathan J Kuwada,Martin J Zuckermann et al.
Elizabeth H C Bromley et al.
Biomolecular motors have inspired the design and construction of artificial nanoscale motors and machines based on nucleic acids, small molecules, and inorganic nanostructures. However, the high degree of sophistication and efficiency of bi...
Pak3 inhibits local actin filament formation to regulate global cell polarity [0.03%]
Pak3通过抑制局部肌动蛋白丝形成来调节细胞极性
Y Asano,A Jiménez-Dalmaroni,T B Liverpool et al.
Y Asano et al.
Lamellipodia are broad actin-based structures that define the protruding edge of many motile animal cells. Here we identify a Drosophila homolog of the p21-activated kinases (Paks) as a novel inhibitor of Rac-mediated lamellipodial formatio...
Stephen J Eglen,Julijana Gjorgjieva
Stephen J Eglen
Sensory maps in the nervous system often connect to each other in a topographic fashion. This is most strikingly seen in the visual system, where neighboring neurons in the retina project to neighboring neurons in the target structure, such...
Highly thermosensitive Ca dynamics in a HeLa cell through IP(3) receptors [0.03%]
通过IP3受体在HeLa细胞中进行高度热敏的钙离子动态学研究
Vadim Tseeb,Madoka Suzuki,Kotaro Oyama et al.
Vadim Tseeb et al.
Intracellular Ca(2+) distribution and its dynamics are essential for various cellular functions. We show with single HeLa cells that a microscopic heat pulse induces Ca(2+) uptake into intracellular stores during heating and Ca(2+) release ...