Genome-Wide Profiling of RNA from Dried Blood Spots: Convergence with Bioinformatic Results Derived from Whole Venous Blood and Peripheral Blood Mononuclear Cells [0.03%]
来源于干血滴纸片的全基因组RNA谱分析及其与静脉血和外周血单个核细胞 bioinformatic结果的一致性研究
Thomas W McDade,Kharah M Ross,Ruby L Fried et al.
Thomas W McDade et al.
Genome-wide transcriptional profiling has emerged as a powerful tool for analyzing biological mechanisms underlying social gradients in health, but utilization in population-based studies has been hampered by logistical constraints and cost...
An Old Mom Keeps You Young: Mother's Age at Last Birth and Offspring Longevity in Nineteenth-Century Utah [0.03%]
老妈养你久——19世纪犹他州母亲高龄生产与子女长寿的关系
Saskia Hin,Bartosz Ogórek,Finn Hedefalk
Saskia Hin
This study analyzes the intergenerational effects of late childbearing on offspring's adult longevity in a population in Utah (United States) that does not display evidence of parity-specific birth control-a so-called natural fertility popu...
The Changing Body Mass-Mortality Association in the United States: Evidence of Sex-Specific Cohort Trends from Three National Health and Nutrition Examination Surveys [0.03%]
基于三次全美健康与营养调查的证据：美国体重-死亡率关系的变化及性别差异
Yan Yu
Yan Yu
The association between body mass index (BMI) categories and mortality remains uncertain. Using three National Health and Nutrition Examination Surveys covering the 1971-2006 period for cohorts born between 1896 and 1968, this study estimat...
The Geographic Distribution of Genetic Risk as Compared to Social Risk for Chronic Diseases in the United States [0.03%]
美国慢性病的遗传风险与社会风险的地域分布比较
David H Rehkopf,Benjamin W Domingue,Mark R Cullen
David H Rehkopf
There is an association between chronic disease and geography, and there is evidence that the environment plays a critical role in this relationship. Yet at the same time, there is known to be substantial geographic variation by ancestry ac...
Differential Vulnerability to Early-Life Parental Death: The Moderating Effects of Family Suicide History on Risks for Major Depression and Substance Abuse in Later Life [0.03%]
童年丧亲导致重性抑郁和物质使用障碍的高危效应：自杀家族史的调节作用
Michael S Hollingshaus,Hilary Coon,Sheila E Crowell et al.
Michael S Hollingshaus et al.
Only a portion of those individuals exposed to parental death in early life (PDE) develop behavioral health disorders. We utilized demographic pedigree data from the Utah Population Database to test for differential vulnerability to PDE by ...
Neighborhood and Family Environment of Expectant Mothers May Influence Prenatal Programming of Adult Cancer Risk: Discussion and an Illustrative DNA Methylation Example [0.03%]
母亲的邻里和家庭环境可能会影响胎儿癌症风险的发育起源：讨论及一个表观遗传修饰实例的说明
Katherine E King,Jennifer B Kane,Peter Scarbrough et al.
Katherine E King et al.
Childhood stressors including physical abuse predict adult cancer risk. Prior research portrays this finding as an indirect mechanism that operates through coping behaviors, including adult smoking, or through increased toxic exposures duri...
Estimating Telomere Length Heritability in an Unrelated Sample of Adults: Is Heritability of Telomere Length Modified by Life Course Socioeconomic Status? [0.03%]
基于成人非亲属样本估计端粒长度遗传度：一生中的社会经济状态是否改变端粒长度的可遗传性？
Jessica D Faul,Colter M Mitchell,Jennifer A Smith et al.
Jessica D Faul et al.
Telomere length (TL) is a widely used marker of biological aging and is associated with an increased risk of morbidity and mortality. Recently, there has been evidence for an association between TL and socioeconomic status (SES), particular...
Genetic Diversity and Differentiation in Urban and Indigenous Populations of Mexico: Patterns of Mitochondrial DNA and Y-Chromosome Lineages [0.03%]
墨西哥城市与土著人口的线粒体DNA和Y染色体谱系的遗传多样性及分化模式
Blanca Z González-Sobrino,Ana P Pintado-Cortina,Leticia Sebastián-Medina et al.
Blanca Z González-Sobrino et al.
Aside from the admixture between indigenous people and people from overseas, populations in Mexico changed drastically after the Spanish conquest of the sixteenth century, forming an intricate history that has been underutilized in understa...
Jeffrey S Napierala,Timothy Gage
Jeffrey S Napierala
A small but growing body of literature examines the relationship between genetics and human migration. These studies suggest that some DRD4 alleles, particularly 7R+, are related to migration. This is surprising from a sociological perspect...
African Ancestry, Social Factors, and Hypertension Among Non-Hispanic Blacks in the Health and Retirement Study [0.03%]
健康与退休研究中的非西班牙裔黑人之非洲血统、社会因素和高血压状况
Jessica R Marden,Stefan Walter,Jay S Kaufman et al.
Jessica R Marden et al.
The biomedical literature contains much speculation about possible genetic explanations for the large and persistent black-white disparities in hypertension, but profound social inequalities are also hypothesized to contribute to this outco...